Item Type | Name |
Academic Article
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Correlation of MCP1 with toxicity in acetaminophen overdose.
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Academic Article
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Acetaminophen-induced hepatotoxicity.
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Academic Article
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Cytokines and toxicity in acetaminophen overdose.
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Academic Article
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Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition.
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Academic Article
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Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation.
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Academic Article
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Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose.
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Academic Article
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Mechanisms of acetaminophen-induced liver necrosis.
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Academic Article
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Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice.
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Academic Article
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Acetaminophen hepatotoxicity and HIF-1a induction in acetaminophen toxicity in mice occurs without hypoxia.
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Academic Article
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Pharmacokinetics and tolerability of rabeprazole sodium in subjects aged 12 to 16 years with gastroesophageal reflux disease: an open-label, single- and multiple-dose study.
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Academic Article
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Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure.
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Academic Article
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Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity.
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Academic Article
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Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase.
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Academic Article
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Prescription-acquired acetaminophen use and the risk of asthma in adults: a case-control study.
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Academic Article
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Hair drug testing of children suspected of exposure to the manufacture of methamphetamine.
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Academic Article
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A multicenter, randomized, open-label, pharmacokinetics and safety study of pantoprazole tablets in children and adolescents aged 6 through 16 years with gastroesophageal reflux disease.
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Academic Article
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Elevation of serum interleukin 8 levels in acetaminophen overdose in children and adolescents.
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Academic Article
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K2 toxicity: fatal case of psychiatric complications following AM2201 exposure.
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Academic Article
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Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds.
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Academic Article
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Echinomycin decreases induction of vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity in mice.
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Academic Article
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Population pharmacokinetics of piperacillin using scavenged samples from preterm infants.
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Academic Article
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Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants.
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Academic Article
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Effect of trifluoperazine on toxicity, HIF-1a induction and hepatocyte regeneration in acetaminophen toxicity in mice.
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Academic Article
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UGT1A9, UGT2B7, and MRP2 genotypes can predict mycophenolic acid pharmacokinetic variability in pediatric kidney transplant recipients.
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Academic Article
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Sulfaphenazole and a-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice.
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Academic Article
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Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases.
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Academic Article
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Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity.
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Academic Article
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Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?
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Academic Article
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Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.
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Academic Article
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Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine.
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Academic Article
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Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
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Academic Article
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Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations.
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Academic Article
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Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure.
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Academic Article
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Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.
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Academic Article
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Predictors of outcome after acetaminophen poisoning in children and adolescents.
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Academic Article
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Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands.
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Academic Article
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Predicting risk in patients with acetaminophen overdose.
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Concept
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Ethanol
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Concept
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Aminoglycosides
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Concept
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Antigens, Ly
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Concept
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Acetylcysteine
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Concept
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Transaminases
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Concept
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Anti-Inflammatory Agents, Non-Steroidal
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Concept
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Blood Proteins
|
Concept
|
Analgesics, Opioid
|
Concept
|
Antibodies, Viral
|
Concept
|
Bilirubin
|
Concept
|
Cannabidiol
|
Concept
|
Bronchodilator Agents
|
Concept
|
Chlorides
|
Concept
|
Chloroform
|
Concept
|
Creatinine
|
Concept
|
Cysteine
|
Concept
|
Anti-Infective Agents
|
Concept
|
Cytochrome P-450 Enzyme System
|
Concept
|
Coloring Agents
|
Concept
|
Anti-Bacterial Agents
|
Concept
|
Deuterium
|
Concept
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Aspartate Aminotransferases
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Concept
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Ampicillin
|
Concept
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Autoantibodies
|
Concept
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Acetaminophen
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Concept
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Antioxidants
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Concept
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Antivenins
|
Concept
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Central Nervous System Stimulants
|
Concept
|
Anti-Ulcer Agents
|
Concept
|
Amphetamine
|
Concept
|
Alanine Transaminase
|
Concept
|
Anti-Inflammatory Agents
|
Concept
|
Antidotes
|
Concept
|
Albuterol
|
Concept
|
Guanidines
|
Concept
|
Histamine
|
Concept
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Hydroxyurea
|
Concept
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Alanine
|
Concept
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Butylene Glycols
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Concept
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Cannabis
|
Concept
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Carbachol
|
Concept
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Immunoglobulin Fab Fragments
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Concept
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Caffeine
|
Concept
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Hydrogen Peroxide
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Concept
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DNA, Viral
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Concept
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Dopamine
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Concept
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Dose-Response Relationship, Drug
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Concept
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Echinomycin
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Concept
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Bile Acids and Salts
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Concept
|
Calcitonin
|
Concept
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C-Reactive Protein
|
Concept
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Aryl Hydrocarbon Hydroxylases
|
Concept
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Binding Sites
|
Concept
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Cannabinoids
|
Concept
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Gastrointestinal Agents
|
Concept
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Delayed-Action Preparations
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Concept
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Glycodeoxycholic Acid
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Concept
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Drug Resistance
|
Concept
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Interleukin-3
|
Concept
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Ketamine
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Concept
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Enzyme Inhibitors
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Concept
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Spider Venoms
|
Concept
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Ion Channels
|
Concept
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Powders
|
Concept
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Drug Synergism
|
Concept
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Glutamate Dehydrogenase
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Concept
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Mixed Function Oxygenases
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Concept
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Prostaglandin-Endoperoxide Synthases
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Concept
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Imines
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Concept
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Prodrugs
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Concept
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Tablets
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Concept
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Membrane Glycoproteins
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Concept
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Myoglobin
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Concept
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Mycophenolic Acid
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Concept
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Plant Extracts
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Concept
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Oxygen
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Concept
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Triazoles
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Concept
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Histamine H2 Antagonists
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Concept
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Pyrans
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Concept
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Calcitonin Gene-Related Peptide
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Concept
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RNA, Viral
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Concept
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Cytochrome P-450 CYP1A2
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Concept
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Interleukin-6
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Concept
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Isoniazid
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Concept
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Proteins
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Concept
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Superoxide Dismutase
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Concept
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Capsules
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Concept
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Nitric Oxide
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Concept
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Proliferating Cell Nuclear Antigen
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Concept
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Protein Precursors
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Concept
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Chemokine CCL2
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Concept
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Sulfaphenazole
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Concept
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Reference Standards
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Concept
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Tyrosine
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Concept
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Recombinant Proteins
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Concept
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Glucuronic Acid
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Concept
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Fas Ligand Protein
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Concept
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Neuroprotective Agents
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Concept
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Trifluoperazine
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Concept
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HMGB1 Protein
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Concept
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Glutathione Transferase
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Concept
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3' Untranslated Regions
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Concept
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Expectorants
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Concept
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Glycochenodeoxycholic Acid
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Concept
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Hallucinogens
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Concept
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Glutathione
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Concept
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Glycerol-3-Phosphate O-Acyltransferase
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Concept
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DNA
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Concept
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Drug Interactions
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Concept
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Lipopolysaccharides
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Concept
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NAD
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Concept
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Teicoplanin
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Concept
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Nitroimidazoles
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Concept
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Phosphatidic Acids
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Concept
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Vancomycin
|
Concept
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Vitamin D
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 1
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Concept
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Interleukin-8
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Concept
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Environmental Pollutants
|
Concept
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Cytochrome P-450 CYP2E1
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Concept
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Glutathione Disulfide
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Concept
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Receptors, Vascular Endothelial Growth Factor
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Concept
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Benzodioxoles
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Concept
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Multidrug Resistance-Associated Proteins
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Concept
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Glucose
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Concept
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Nitric Oxide Synthase Type I
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Concept
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Prescription Drugs
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Concept
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Drug Compounding
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Concept
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Benzoflavones
|
Concept
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Caustics
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Concept
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HSP72 Heat-Shock Proteins
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Concept
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2-Pyridinylmethylsulfinylbenzimidazoles
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Concept
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Carnitine
|
Concept
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Mitochondrial Membrane Transport Proteins
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Concept
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Cesium
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Concept
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Indocyanine Green
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Concept
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Glucuronidase
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Concept
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Methylamines
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Concept
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Nitrates
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Concept
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Insulin
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Concept
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JNK Mitogen-Activated Protein Kinases
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Concept
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Fentanyl
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Concept
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Pyruvic Acid
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Concept
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Styrene
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Concept
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Receptors, Tumor Necrosis Factor, Type I
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Concept
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Metronidazole
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Ligands
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Concept
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Indicators and Reagents
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Concept
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Indoles
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Concept
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Crotalid Venoms
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Concept
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Amine Oxidase (Copper-Containing)
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Concept
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Immunosuppressive Agents
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Concept
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Granzymes
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Concept
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Immunoglobulin Fragments
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Concept
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Lipids
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Concept
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Sulfuric Acids
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Concept
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Piperacillin
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Concept
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Methamphetamine
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Concept
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Naphthalenes
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Concept
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Psychotropic Drugs
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Concept
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Endopeptidases
|
Concept
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Vitamins
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Concept
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Dinoprostone
|
Concept
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Pentanones
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Concept
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Phosphatidate Phosphatase
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Concept
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Superoxides
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Concept
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Suramin
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Concept
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Taurodeoxycholic Acid
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Concept
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Glucuronosyltransferase
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Concept
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Tumor Necrosis Factor-alpha
|
Concept
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Chemokines
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Concept
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Receptor, Cannabinoid, CB1
|
Concept
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Sulfonamides
|
Concept
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Pyrrolidines
|
Concept
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Reactive Oxygen Species
|
Concept
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Intercellular Signaling Peptides and Proteins
|
Concept
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Apoptosis
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Concept
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Famotidine
|
Concept
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Anti-Asthmatic Agents
|
Concept
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Glucuronides
|
Concept
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Cyclosporine
|
Concept
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Proton Pump Inhibitors
|
Concept
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Keratin-8
|
Concept
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Free Radical Scavengers
|
Concept
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Hypoxia-Inducible Factor 1
|
Concept
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Drug Administration Schedule
|
Concept
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Interleukin-10
|
Concept
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Reactive Nitrogen Species
|
Concept
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Benzoquinones
|
Concept
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Peroxynitrous Acid
|
Concept
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Nitric Oxide Synthase
|
Concept
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beta Catenin
|
Concept
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Omeprazole
|
Concept
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Vascular Endothelial Growth Factor A
|
Concept
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Analgesics, Non-Narcotic
|
Concept
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Sirtuin 1
|
Concept
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Drug Overdose
|
Concept
|
Cytochrome P-450 CYP3A
|
Concept
|
Thiazolidinediones
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily B
|
Concept
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TOR Serine-Threonine Kinases
|
Concept
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Keratin-18
|
Concept
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Receptors, Phospholipase A2
|
Concept
|
ortho-Aminobenzoates
|
Concept
|
Drug Dosage Calculations
|
Concept
|
Phosphoric Diester Hydrolases
|
Concept
|
Sodium Oxybate
|
Concept
|
Vitamin A
|
Concept
|
Protein Isoforms
|
Concept
|
MicroRNAs
|
Concept
|
Nuclear Proteins
|
Concept
|
Designer Drugs
|
Concept
|
Cytokines
|
Concept
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Macrolides
|
Academic Article
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Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.
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Academic Article
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Isoniazid hepatotoxicity: progress in understanding the immunologic component.
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Academic Article
|
marijuana-based drugs: Innovateive therapeutics or designer drugs of abuse
|
Academic Article
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Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice
|
Academic Article
|
Adverse Drug Reactions, Handbook of Experimental Pharmacology
|
Academic Article
|
Pediatric and Neonatal Pharmacology
|
Academic Article
|
P450-mediated oxidative metabolism of abused synthetic cannabinoids found in “K2/Spice”: identification of novel cannabinoid receptor ligands
|
Academic Article
|
UGT1A9, UGTB7, and MRP2 genotypes can predict mycophenolic acid pharmacokinetic variability in pediatric kidney transplant recipients
|
Academic Article
|
Conjugation of JWH-018 and JWH-073 metabolites by human UDP-glucuronosyltransferases
|
Academic Article
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Sympathormimetic drug use in adolescents presenting to a pediatric emergency department with chrest pain
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Academic Article
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Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children.
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Academic Article
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Acetaminophen Adducts Detected in Serum of Pediatric Patients With Acute Liver Failure.
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Academic Article
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A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes.
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Academic Article
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Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity.
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Academic Article
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Translational biomarkers of acetaminophen-induced acute liver injury.
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Academic Article
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The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.
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Academic Article
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MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity.
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Academic Article
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Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates.
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Academic Article
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Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling.
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Academic Article
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Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures.
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Academic Article
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Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.
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Academic Article
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Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants.
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Academic Article
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A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents.
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Academic Article
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Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.
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Academic Article
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The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3? and Wnt/?-catenin signaling.
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Academic Article
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Pharmacokinetics, Safety, and Tolerability of Single-Dose Intravenous Moxifloxacin in Pediatric Patients: Dose Optimization in a Phase 1 Study.
|
Grant
|
AcetaSTAT Rapid Assay for Acetaminophen Liver Injury
|
Grant
|
Pediatric Pharmacology Research Unit Network
|
Grant
|
NOVEL THERAPIES FOR ACETAMINOPHEN TOXICITY
|
Grant
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Identification of new mechanistic biomarkers of adverse responses to acetaminophe
|
Grant
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Dipstick Assay for Detection of Acetaminophen Protein Adducts
|
Grant
|
Evaluation of a Biomarker for Acetaminophen Toxicity
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Academic Article
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Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality.
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Academic Article
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Acetaminophen Protein Adducts in Hospitalized Children Receiving Multiple Doses of Acetaminophen.
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Academic Article
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Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.
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Academic Article
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Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children.
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Academic Article
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Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5).
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Academic Article
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Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice.
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Academic Article
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The Spice of Death: Sudden Cardiac Arrest After Novel Psychoactive Substance Exposure.
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Academic Article
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Short-Term Safety of Repeated Acetaminophen Use in Patients With Compensated Cirrhosis.
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Academic Article
|
Hands-Free Analytical Urine Testing Technology Validated for Drug-Facilitated Crime Investigations.
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Academic Article
|
Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult.
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