 Sirtuin 1
"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
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| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
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| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
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Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in UAMS Profiles by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 3 | 1 | 4 | | 2013 | 0 | 2 | 2 | | 2012 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles over the past ten years.
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Nada EM, El-Gharbawy NM, Abbas H, Werida RH. Effect of adding fenofibrate versus curcumin to glimepiride in patients with type 2 diabetes: a randomized controlled trial. BMC Pharmacol Toxicol. 2025 Jun 06; 26(1):119.
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Daneshgar N, Lan R, Regnier M, Mackintosh SG, Venkatasubramanian R, Dai DF. Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways. Geroscience. 2024 Oct; 46(5):4729-4741.
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Rada P, Pardo V, Mobasher MA, Garc?a-Mart?nez I, Ruiz L, Gonz?lez-Rodr?guez ?, Sanchez-Ramos C, Muntan? J, Alemany S, James LP, Simpson KJ, Monsalve M, Valdecantos MP, Valverde ?M. SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress. Antioxid Redox Signal. 2018 05 01; 28(13):1187-1208.
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