Acetylcysteine
"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.
Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".
Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".
This graph shows the total number of publications written about "Acetylcysteine" by people in UAMS Profiles by year, and whether "Acetylcysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 2 | 2 | 2020 | 0 | 1 | 1 | 2019 | 1 | 2 | 3 | 2017 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2014 | 1 | 3 | 4 | 2013 | 2 | 1 | 3 | 2012 | 1 | 0 | 1 | 2011 | 2 | 1 | 3 | 2010 | 3 | 5 | 8 | 2009 | 0 | 3 | 3 | 2008 | 1 | 2 | 3 | 2007 | 1 | 3 | 4 | 2006 | 1 | 4 | 5 | 2005 | 2 | 1 | 3 | 2004 | 0 | 2 | 2 | 2003 | 1 | 1 | 2 | 2002 | 2 | 1 | 3 | 2001 | 0 | 1 | 1 | 2000 | 1 | 1 | 2 | 1999 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylcysteine" by people in Profiles over the past ten years.
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Filip AB, Mullins ME. Fomepizole should be used more liberally in paracetamol overdose. Br J Clin Pharmacol. 2023 02; 89(2):594-598.
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Filip AB, Berg SE, Mullins ME, Schwarz ES. Fomepizole as an adjunctive therapy for acetaminophen poisoning: cases reported to the toxicology investigators consortium (ToxIC) database 2015-2020. Clin Toxicol (Phila). 2022 09; 60(9):1006-1011.
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Baumgartner K, Filip A, Liss D, Devgun J, Schwarz E, Mullins M. N-acetylcysteine for acetaminophen toxicity: The one-bag regimen. Br J Clin Pharmacol. 2021 05; 87(5):2399-2400.
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Kathuria A, Lopez-Lengowski K, Watmuff B, McPhie D, Cohen BM, Karmacharya R. Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine. Transl Psychiatry. 2019 11 28; 9(1):321.
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Chiew AL, James LP, Isbister GK, Pickering JW, McArdle K, Chan BSH, Buckley NA. Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5). J Hepatol. 2020 03; 72(3):450-462.
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Khanal T, Leung YK, Jiang W, Timchenko N, Ho SM, Kim K. NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries. FASEB J. 2019 07; 33(7):8335-8348.
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Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. Mice lacking liver-specific ?-catenin develop steatohepatitis and fibrosis after iron overload. J Hepatol. 2017 08; 67(2):360-369.
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Banerjee S, Aykin-Burns N, Krager KJ, Shah SK, Melnyk SB, Hauer-Jensen M, Pawar SA. Loss of C/EBPd enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction. Free Radic Biol Med. 2016 10; 99:296-307.
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El-Ebiary AA, Elsharkawy RE, Soliman NA, Soliman MA, Hashem AA. N-acetylcysteine in Acute Organophosphorus Pesticide Poisoning: A Randomized, Clinical Trial. Basic Clin Pharmacol Toxicol. 2016 Aug; 119(2):222-7.
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Slattery J, Kumar N, Delhey L, Berk M, Dean O, Spielholz C, Frye R. Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review. Neurosci Biobehav Rev. 2015 Aug; 55:294-321.
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