 Drug Resistance
"Drug Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
| Descriptor ID |
D004351
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| MeSH Number(s) |
G07.690.320
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Drug Resistance".
Below are MeSH descriptors whose meaning is more specific than "Drug Resistance".
This graph shows the total number of publications written about "Drug Resistance" by people in UAMS Profiles by year, and whether "Drug Resistance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2014 | 1 | 3 | 4 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2008 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2005 | 1 | 3 | 4 | | 2004 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 1997 | 0 | 2 | 2 | | 1996 | 0 | 2 | 2 | | 1994 | 1 | 1 | 2 | | 1992 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Drug Resistance" by people in Profiles over the past ten years.
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Chen G, Gao X, Jia X, Wang Y, Xu L, Yu D, Chang S, Deng H, Hu K, Wang G, Li B, Xu Z, Lu Y, Wang H, Zhang T, Song D, Yang G, Wu X, Zhu H, Zhu W, Shi J. Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma. Haematologica. 2024 04 01; 109(4):1206-1219.
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Abedin S, Rashid N, Schroeder M, Romee R, Nauffal M, Alhaj Moustafa M, Kharfan-Dabaja MA, Palmer J, Hogan W, Hefazi M, Larson S, Holtan S, DeFilipp Z, Jayani R, Dholaria B, Pidala J, Khimani F, Grunwald MR, Butler C, Hamadani M. Ruxolitinib resistance or intolerance in steroid-refractory acute graft-versus-host disease - a real-world outcomes analysis. Br J Haematol. 2021 11; 195(3):429-432.
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McDonough CW, Babcock K, Chucri K, Crawford DC, Bian J, Modave F, Cooper-DeHoff RM, Hogan WR. Optimizing identification of resistant hypertension: Computable phenotype development and validation. Pharmacoepidemiol Drug Saf. 2020 11; 29(11):1393-1401.
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Meltzer HY, Share DB, Jayathilake K, Salomon RM, Lee MA. Lurasidone Improves Psychopathology and Cognition in Treatment-Resistant Schizophrenia. J Clin Psychopharmacol. 2020 May-Jun; 40(3):240-249.
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Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 08 20; 25(9):1569-1576.
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Thumma S, Idrees S, Phuyal P, Manchala V, Mattana J. When the Standard Treatment Fails: Rituximab Therapy for Refractory TTP. Am J Ther. 2019 Jul/Aug; 26(4):e552-e553.
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Gu C, Jing X, Holman C, Sompallae R, Zhan F, Tricot G, Yang Y, Janz S. Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma. BMC Cancer. 2018 Nov 21; 18(1):1152.
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Hernandez-Suarez DF, Scott SA, Tomey MI, Melin K, Lopez-Candales A, Buckley CE, Duconge J. Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Puerto Rican Hispanics. Ther Adv Cardiovasc Dis. 2017 Sep; 11(9):235-241.
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Williams K, Valencia L, Gokulan K, Trbojevich R, Khare S. Assessment of antimicrobial effects of food contact materials containing silver on growth of Salmonella Typhimurium. Food Chem Toxicol. 2017 Feb; 100:197-206.
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Kucab JE, Hollstein M, Arlt VM, Phillips DH. Nutlin-3a selects for cells harbouring TP53 mutations. Int J Cancer. 2017 02 15; 140(4):877-887.
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Vazir A, Simpkin VL, Marino P, Ludman A, Banya W, Tavazzi G, Bastin AJ, Trenfield S, Ghori A, Alexander PD, Griffiths M, Price S, Sharma R, Cowie MR. Association of haemodynamic changes measured by serial central venous saturation during ultrafiltration for acutely decompensated heart failure with diuretic resistance and change in renal function. Int J Cardiol. 2016 Oct 01; 220:618-22.
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Brotherton AL, Hamilton EP, Kloss HG, Hammond DA. Propofol for Treatment of Refractory Alcohol Withdrawal Syndrome: A Review of the Literature. Pharmacotherapy. 2016 Apr; 36(4):433-42.
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Alawneh A, Tuqan W, Innabi A, Abu-Sheikha A, Al-Arja G, Shehadeh I. Successful Palliation of Octreotide-Resistant Diarrhea Using Glycopyrrolate in a Patient With Medullary Thyroid Cancer: A Case Report. J Pain Symptom Manage. 2015 Sep; 50(3):e4-6.
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Sharp GB, Samanta D, Willis E. Options for pharmacoresistant epilepsy in children: when medications don't work. Pediatr Ann. 2015 Feb; 44(2):e43-8.
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Nyunt MH, Hlaing T, Oo HW, Tin-Oo LL, Phway HP, Wang B, Zaw NN, Han SS, Tun T, San KK, Kyaw MP, Han ET. Molecular assessment of artemisinin resistance markers, polymorphisms in the k13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar. Clin Infect Dis. 2015 Apr 15; 60(8):1208-15.
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