Thiazolidinediones
"Thiazolidinediones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
Descriptor ID |
D045162
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MeSH Number(s) |
D02.886.675.933 D03.383.129.708.933
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thiazolidinediones".
Below are MeSH descriptors whose meaning is more specific than "Thiazolidinediones".
This graph shows the total number of publications written about "Thiazolidinediones" by people in UAMS Profiles by year, and whether "Thiazolidinediones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2023 | 1 | 0 | 1 | 2017 | 1 | 1 | 2 | 2016 | 1 | 1 | 2 | 2015 | 2 | 1 | 3 | 2014 | 1 | 1 | 2 | 2013 | 1 | 1 | 2 | 2012 | 4 | 1 | 5 | 2011 | 0 | 1 | 1 | 2010 | 2 | 1 | 3 | 2009 | 2 | 0 | 2 | 2008 | 4 | 0 | 4 | 2007 | 5 | 1 | 6 | 2006 | 7 | 4 | 11 | 2005 | 5 | 1 | 6 | 2004 | 5 | 0 | 5 | 2003 | 2 | 0 | 2 | 2000 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Thiazolidinediones" by people in Profiles over the past ten years.
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Hameed I, Hayat J, Marsia S, Samad SA, Khan R, Siddiqui OM, Khan MO, Malik S, Fatima K, Fudim M, Krasuski RA. Comparison of sodium-glucose cotransporter-2 inhibitors and thiazolidinediones for management of non-alcoholic fatty liver disease: A systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2023 05; 47(5):102111.
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Lee SM, Muratalla J, Sierra-Cruz M, Cordoba-Chacon J. Role of hepatic peroxisome proliferator-activated receptor ? in non-alcoholic fatty liver disease. J Endocrinol. 2023 04 01; 257(1).
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Tsai CY, Rosa F, Bionaz M, Rezamand P. Effects of 2,4-thiazolidinedione (TZD) on milk fatty acid profile and serum vitamins in dairy goats challenged with intramammary infusion of Streptococcus uberis. J Dairy Res. 2020 Nov; 87(4):416-423.
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Geer EB, Shafiq I, Gordon MB, Bonert V, Ayala A, Swerdloff RS, Katznelson L, Lalazar Y, Manuylova E, Pulaski-Liebert KJ, Carmichael JD, Hannoush Z, Surampudi V, Broder MS, Cherepanov D, Eagan M, Lee J, Said Q, Neary MP, Biller BMK. BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. Endocr Pract. 2017 Aug; 23(8):962-970.
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Cippitelli A, Domi E, Ubaldi M, Douglas JC, Li HW, Demopulos G, Gaitanaris G, Roberto M, Drew PD, Kane CJM, Ciccocioppo R. Protection against alcohol-induced neuronal and cognitive damage by the PPAR? receptor agonist pioglitazone. Brain Behav Immun. 2017 Aug; 64:320-329.
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Chen JR, Lazarenko OP, Blackburn ML, Rose S, Frye RE, Badger TM, Andres A, Shankar K. Maternal Obesity Programs Senescence Signaling and Glucose Metabolism in Osteo-Progenitors From Rat and Human. Endocrinology. 2016 Nov; 157(11):4172-4183.
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Bilandzic A, Fitzpatrick T, Rosella L, Henry D. Risk of Bias in Systematic Reviews of Non-Randomized Studies of Adverse Cardiovascular Effects of Thiazolidinediones and Cyclooxygenase-2 Inhibitors: Application of a New Cochrane Risk of Bias Tool. PLoS Med. 2016 Apr; 13(4):e1001987.
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Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial. Lancet Neurol. 2015 Aug; 14(8):795-803.
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Takagi M, Sakamoto M, Itoh T, Fujiwara R. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. Drug Metab Pharmacokinet. 2015 Aug; 30(4):288-94.
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Walton RG, Zhu B, Unal R, Spencer M, Sunkara M, Morris AJ, Charnigo R, Katz WS, Daugherty A, Howatt DA, Kern PA, Finlin BS. Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. J Biol Chem. 2015 May 01; 290(18):11547-56.
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Dunn TN, Akiyama T, Lee HW, Kim JB, Knotts TA, Smith SR, Sears DD, Carstens E, Adams SH. Evaluation of the synuclein-? (SNCG) gene as a PPAR? target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue. PLoS One. 2015; 10(3):e0115830.
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Drew PD, Johnson JW, Douglas JC, Phelan KD, Kane CJ. Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. Alcohol Clin Exp Res. 2015 Mar; 39(3):445-54.
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