Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

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Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

Muldrew KL, James LP, Coop L, McCullough SS, Hendrickson HP, Hinson JA, Mayeux PR. Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection. Drug Metab Dispos. 2002 Apr; 30(4):446-51.

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subject areas

Acetaminophen
Adolescent
Alanine Transaminase
Analgesics, Non-Narcotic
Animals
Aspartate Aminotransferases
Child
Chromatography, High Pressure Liquid
Cysteine
Endopeptidases
Humans
Liver
Male
Mice
Mice, Inbred C57BL
Predictive Value of Tests
Proteins
Sensitivity and Specificity
Time Factors
Tyrosine

authors with profiles

Laura James