 Aryl Hydrocarbon Hydroxylases
"Aryl Hydrocarbon Hydroxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
| Descriptor ID |
D001189
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| MeSH Number(s) |
D08.244.453.040 D08.811.682.690.708.170.040 D12.776.422.220.453.040
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aryl Hydrocarbon Hydroxylases".
Below are MeSH descriptors whose meaning is more specific than "Aryl Hydrocarbon Hydroxylases".
This graph shows the total number of publications written about "Aryl Hydrocarbon Hydroxylases" by people in UAMS Profiles by year, and whether "Aryl Hydrocarbon Hydroxylases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 2 | 3 | | 2012 | 1 | 1 | 2 | | 2011 | 0 | 2 | 2 | | 2010 | 3 | 1 | 4 | | 2009 | 2 | 1 | 3 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2006 | 1 | 2 | 3 | | 2005 | 2 | 0 | 2 | | 2004 | 1 | 2 | 3 | | 2003 | 3 | 2 | 5 | | 2002 | 1 | 3 | 4 | | 2001 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1994 | 3 | 0 | 3 | | 1993 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aryl Hydrocarbon Hydroxylases" by people in Profiles over the past ten years.
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Reed L, Indra R, Mrizova I, Moserova M, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM. Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine. Toxicol Appl Pharmacol. 2019 03 01; 366:64-74.
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Hye Khan MA, Fish B, Wahl G, Sharma A, Falck JR, Paudyal MP, Moulder JE, Imig JD, Cohen EP. Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy. Clin Sci (Lond). 2016 Apr; 130(8):587-99.
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Takagi M, Sakamoto M, Itoh T, Fujiwara R. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. Drug Metab Pharmacokinet. 2015 Aug; 30(4):288-94.
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