 Proliferating Cell Nuclear Antigen
"Proliferating Cell Nuclear Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
| Descriptor ID |
D018809
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| MeSH Number(s) |
D12.776.660.740 D23.050.290.750 D23.101.840.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proliferating Cell Nuclear Antigen".
Below are MeSH descriptors whose meaning is more specific than "Proliferating Cell Nuclear Antigen".
This graph shows the total number of publications written about "Proliferating Cell Nuclear Antigen" by people in UAMS Profiles by year, and whether "Proliferating Cell Nuclear Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2015 | 1 | 0 | 1 | | 2012 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2009 | 1 | 3 | 4 | | 2008 | 0 | 4 | 4 | | 2007 | 0 | 4 | 4 | | 2006 | 0 | 1 | 1 | | 2005 | 3 | 1 | 4 | | 2004 | 0 | 1 | 1 | | 2003 | 2 | 6 | 8 | | 2002 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proliferating Cell Nuclear Antigen" by people in Profiles over the past ten years.
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Bhandari SK, Wiest N, Sallmyr A, Du R, Ferry L, Defossez PA, Tomkinson AE. Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1. Sci Rep. 2023 03 16; 13(1):4363.
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Logan C, Lyzogubov V, Bora N, Bora P. Role of Adiponectin Peptide I (APNp1) in Age-Related Macular Degeneration. Biomolecules. 2022 09 03; 12(9).
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Lahiani MH, Gokulan K, Williams K, Khare S. Ex Vivo Human Colon Tissue Exposure to Pristine Graphene Activates Genes Involved in the Binding, Adhesion and Proliferation of Epithelial Cells. Int J Mol Sci. 2021 Oct 23; 22(21).
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Clemens MM, Kennon-McGill S, Apte U, James LP, Finck BN, McGill MR. The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3? and Wnt/?-catenin signaling. Food Chem Toxicol. 2019 Mar; 125:279-288.
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Choubey M, Ranjan A, Bora PS, Baltazar F, Martin LJ, Krishna A. Role of adiponectin as a modulator of testicular function during aging in mice. Biochim Biophys Acta Mol Basis Dis. 2019 02 01; 1865(2):413-427.
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Ronis MJ, Gomez-Acevedo H, Blackburn ML, Cleves MA, Singhal R, Badger TM. Uterine responses to feeding soy protein isolate and treatment with 17?-estradiol differ in ovariectomized female rats. Toxicol Appl Pharmacol. 2016 Apr 15; 297:68-80.
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Maes M, McGill MR, da Silva TC, Lebofsky M, Maria Monteiro de Ara?jo C, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Zaidan Dagli ML, Jaeschke H, Cogliati B, Vinken M. Connexin32: a mediator of acetaminophen-induced liver injury? Toxicol Mech Methods. 2016 Feb; 26(2):88-96.
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Khalil MI, Ibrahim MM, El-Gaaly GA, Sultan AS. Trigonella foenum (Fenugreek) Induced Apoptosis in Hepatocellular Carcinoma Cell Line, HepG2, Mediated by Upregulation of p53 and Proliferating Cell Nuclear Antigen. Biomed Res Int. 2015; 2015:914645.
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Majed F, Rashid S, Khan AQ, Nafees S, Ali N, Ali R, Khan R, Hasan SK, Mehdi SJ, Sultana S. Tannic acid mitigates the DMBA/croton oil-induced skin cancer progression in mice. Mol Cell Biochem. 2015 Jan; 399(1-2):217-28.
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