 Drug Interactions
"Drug Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
| Descriptor ID |
D004347
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| MeSH Number(s) |
G07.690.812.240 G07.700.680.240
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| Concept/Terms |
Drug Interactions- Drug Interactions
- Drug Interaction
- Interaction, Drug
- Interactions, Drug
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Below are MeSH descriptors whose meaning is more general than "Drug Interactions".
Below are MeSH descriptors whose meaning is more specific than "Drug Interactions".
This graph shows the total number of publications written about "Drug Interactions" by people in UAMS Profiles by year, and whether "Drug Interactions" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 1 | 2 | | 2021 | 2 | 2 | 4 | | 2020 | 0 | 2 | 2 | | 2019 | 0 | 2 | 2 | | 2018 | 2 | 4 | 6 | | 2017 | 1 | 3 | 4 | | 2016 | 0 | 6 | 6 | | 2015 | 3 | 0 | 3 | | 2014 | 1 | 1 | 2 | | 2013 | 0 | 5 | 5 | | 2012 | 0 | 6 | 6 | | 2011 | 0 | 8 | 8 | | 2010 | 0 | 7 | 7 | | 2009 | 1 | 8 | 9 | | 2008 | 0 | 4 | 4 | | 2007 | 1 | 9 | 10 | | 2006 | 0 | 10 | 10 | | 2005 | 0 | 13 | 13 | | 2004 | 0 | 7 | 7 | | 2003 | 0 | 6 | 6 | | 2002 | 0 | 8 | 8 | | 2001 | 0 | 7 | 7 | | 2000 | 0 | 4 | 4 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1997 | 0 | 3 | 3 | | 1996 | 0 | 3 | 3 | | 1995 | 0 | 6 | 6 | | 1993 | 0 | 3 | 3 | | 1991 | 0 | 1 | 1 | | 1990 | 0 | 2 | 2 | | 1989 | 0 | 2 | 2 |
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Below are the most recent publications written about "Drug Interactions" by people in Profiles over the past ten years.
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Oslin DW, Lynch KG, Shih MC, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, Aslam M, Batki SL, Bjork JM, Blow FC, Brenner LA, Chen P, Desai S, Dieperink EW, Fears SC, Fuller MA, Goodman CS, Graham DP, Haas GL, Hamner MB, Helstrom AW, Hurley RA, Icardi MS, Jurjus GJ, Kilbourne AM, Kreyenbuhl J, Lache DJ, Lieske SP, Lynch JA, Meyer LJ, Montalvo C, Muralidhar S, Ostacher MJ, Paschall GY, Pfeiffer PN, Prieto S, Przygodzki RM, Ranganathan M, Rodriguez-Suarez MM, Roggenkamp H, Schichman SA, Schneeweis JS, Simonetti JA, Steinhauer SR, Suppes T, Umbert MA, Vassy JL, Voora D, Wiechers IR, Wood AE. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA. 2022 07 12; 328(2):151-161.
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Samanta D. A scoping review on cannabidiol therapy in tuberous sclerosis: Current evidence and perspectives for future development. Epilepsy Behav. 2022 03; 128:108577.
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Ikram H, Tasneem S, Perveen S, Zakir R, Jabeen Haleem D. Neurochemical and behavioral effects of fluoxetine on midazolam induce dependence in an animal model of addiction. Pak J Pharm Sci. 2021 Sep; 34(5):1749-1757.
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Berquist MD, Fantegrossi WE. Effects of 5-HT2A receptor agonist 2,5-dimethoxy-4-iodoamphetamine on alcohol consumption in Long-Evans rats. Behav Pharmacol. 2021 08 01; 32(5):382-391.
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Datta A, Flynn NR, Barnette DA, Woeltje KF, Miller GP, Swamidass SJ. Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort. PLoS Comput Biol. 2021 07; 17(7):e1009053.
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Hoang L, Boyce RD, Bosch N, Stottlemyer B, Brochhausen M, Schneider J. Automatically classifying the evidence type of drug-drug interaction research papers as a step toward computer supported evidence curation. AMIA Annu Symp Proc. 2020; 2020:554-563.
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Ramsey CM, Lynch KG, Thase ME, Gelernter J, Kranzler HR, Pyne JM, Shih MC, Stone A, Oslin DW. Prevalence of predicted gene-drug interactions for antidepressants in the treatment of major depressive disorder in the Precision Medicine in Mental Health Care Study. J Affect Disord. 2021 03 01; 282:1272-1277.
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Barnette DA, Schleiff MA, Datta A, Flynn N, Swamidass SJ, Miller GP. Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam. Toxicol Lett. 2021 Mar 01; 338:10-20.
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Pertzborn MC, Prabhakaran S, Abu-Hasan M, Baker D, Wu S, Wu Y, Hendeles L. Continuous Albuterol With Benzalkonium in Children Hospitalized With Severe Asthma. Pediatrics. 2020 04; 145(4).
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Digala LP, Lucchese S. IV Lidocaine Infusion Leading to the Toxic Levels in Serum Causing Asystole - A Case Report. Headache. 2020 01; 60(1):269-270.
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Hull LE, Chanfreau-Coffinier C, Tuteja S, Berlowitz D, Lehmann LS, Oslin DW, Pyne JM, DuVall SL, Lynch JA. Early adoption of pharmacogenetic testing for veterans prescribed psychotropic medications. Pharmacogenomics. 2019 07; 20(11):781-789.
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Gonzalez-Jimenez A, McEuen K, Chen M, Suzuki A, Robles-Diaz M, Medina-Caliz I, Bessone F, Hernandez N, Arrese M, Parana R, Lucena MI, Stephens C, Andrade RJ. The influence of drug properties and host factors on delayed onset of symptoms in drug-induced liver injury. Liver Int. 2019 02; 39(2):401-410.
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Faria J, Solverson M, Faria M, Benoit M, McCormick M. Potential Cytochrome P450 Drug-Drug Interactions among Pediatric Patients Undergoing Tonsillectomy. Otolaryngol Head Neck Surg. 2019 01; 160(1):145-149.
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Correa A, Rochlani Y, Khan MH, Aronow WS. Pharmacological management of hypertension in the elderly and frail populations. Expert Rev Clin Pharmacol. 2018 Aug; 11(8):805-817.
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Gurley BJ, Tonsing-Carter A, Thomas SL, Fifer EK. Clinically Relevant Herb-Micronutrient Interactions: When Botanicals, Minerals, and Vitamins Collide. Adv Nutr. 2018 07 01; 9(4):524S-532S.
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Judkins J, Tay-Sontheimer J, Boyce RD, Brochhausen M. Extending the DIDEO ontology to include entities from the natural product drug interaction domain of discourse. J Biomed Semantics. 2018 05 09; 9(1):15.
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Gressler LE, Martin BC, Hudson TJ, Painter JT. Relationship between concomitant benzodiazepine-opioid use and adverse outcomes among US veterans. Pain. 2018 03; 159(3):451-459.
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Guimbellot JS, Acosta EP, Rowe SM. Sensitivity of ivacaftor to drug-drug interactions with rifampin, a cytochrome P450 3A4 inducer. Pediatr Pulmonol. 2018 05; 53(5):E6-E8.
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Shi P, Liao M, Chuang BC, Griffin R, Shi J, Hyer M, Fallon JK, Smith PC, Li C, Xia CQ. Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles. Xenobiotica. 2018 Nov; 48(11):1173-1183.
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Amsden JR, Gubbins PO. Pharmacogenomics of triazole antifungal agents: implications for safety, tolerability and efficacy. Expert Opin Drug Metab Toxicol. 2017 Nov; 13(11):1135-1146.
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Utecht J, Brochhausen M, Judkins J, Schneider J, Boyce RD. Formalizing Evidence Type Definitions for Drug-Drug Interaction Studies to Improve Evidence Base Curation. Stud Health Technol Inform. 2017; 245:960-964.
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Tai S, Fantegrossi WE. Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites. Curr Top Behav Neurosci. 2017; 32:249-262.
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Schibler J, Tomanek-Chalkley AM, Reedy JL, Zhan F, Spitz DR, Schultz MK, Goel A. Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells. PLoS One. 2016; 11(11):e0167323.
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Rush JL, Ibrahim J, Saul K, Brodell RT. Improving Patient Safety by Combating Alert Fatigue. J Grad Med Educ. 2016 Oct; 8(4):620-621.
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Haarhoff ZE, Kramer MA, Zvyaga TA, Zhang J, Bhutani P, Subramanian M, Rodrigues AD. Comprehensive evaluation of liver microsomal cytochrome P450 3A (CYP3A) inhibition: comparison of cynomolgus monkey and human. Xenobiotica. 2017 Jun; 47(6):470-478.
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Casserly EA, Rogers SE, Keisner SV. Lack of interaction between enzalutamide and warfarin in a metastatic castration-resistant prostate cancer patient. J Oncol Pharm Pract. 2017 Jan; 23(1):68-70.
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Berquist MD, Traxler HK, Mahler AM, Baker LE. Sensitization to the locomotor stimulant effects of "bath salt" constituents, 4-methylmethcathinone (4-MMC) and 3,4-methylenedioxypyrovalerone (MDPV), in male Sprague-Dawley rats. Drug Alcohol Depend. 2016 Jul 01; 164:128-134.
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Dayer L, Dunn E, Pace A, Flowers S. Pharmacists' perceived knowledge of and confidence in dispensing oral antineoplastic agents. J Am Pharm Assoc (2003). 2016 Mar-Apr; 56(2):141-4.e2.
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Suzuki A, Yuen NA, Ilic K, Miller RT, Reese MJ, Brown HR, Ambroso JI, Falls JG, Hunt CM. Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase?. Regul Toxicol Pharmacol. 2015 Aug; 72(3):481-90.
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Takagi M, Sakamoto M, Itoh T, Fujiwara R. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. Drug Metab Pharmacokinet. 2015 Aug; 30(4):288-94.
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Ayvaz S, Horn J, Hassanzadeh O, Zhu Q, Stan J, Tatonetti NP, Vilar S, Brochhausen M, Samwald M, Rastegar-Mojarad M, Dumontier M, Boyce RD. Toward a complete dataset of drug-drug interaction information from publicly available sources. J Biomed Inform. 2015 Jun; 55:206-17.
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Chen M, Suzuki A, Borlak J, Andrade RJ, Lucena MI. Drug-induced liver injury: Interactions between drug properties and host factors. J Hepatol. 2015 Aug; 63(2):503-14.
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Oda S, Fujiwara R, Kutsuno Y, Fukami T, Itoh T, Yokoi T, Nakajima M. Targeted screen for human UDP-glucuronosyltransferases inhibitors and the evaluation of potential drug-drug interactions with zafirlukast. Drug Metab Dispos. 2015 Jun; 43(6):812-8.
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