 JNK Mitogen-Activated Protein Kinases
"JNK Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.
| Descriptor ID |
D048031
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.513 D08.811.913.696.620.682.700.646.750.374 D12.644.360.450.340 D12.776.476.450.340
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| Concept/Terms |
JNK Mitogen-Activated Protein Kinases- JNK Mitogen-Activated Protein Kinases
- JNK Mitogen Activated Protein Kinases
- jun-NH2-Terminal Kinases
- jun NH2 Terminal Kinases
- jun-NH2-Terminal Kinase
- jun NH2 Terminal Kinase
- c-jun Amino-Terminal Kinase
- Amino-Terminal Kinase, c-jun
- c jun Amino Terminal Kinase
- c-jun N-Terminal Kinase
- N-Terminal Kinase, c-jun
- c jun N Terminal Kinase
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Below are MeSH descriptors whose meaning is more general than "JNK Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "JNK Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "JNK Mitogen-Activated Protein Kinases" by people in UAMS Profiles by year, and whether "JNK Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2021 | 0 | 1 | 1 | | 2015 | 3 | 4 | 7 | | 2014 | 2 | 2 | 4 | | 2013 | 1 | 2 | 3 | | 2012 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2009 | 3 | 2 | 5 | | 2008 | 1 | 0 | 1 | | 2007 | 3 | 2 | 5 | | 2006 | 1 | 3 | 4 | | 2005 | 2 | 1 | 3 | | 2004 | 0 | 4 | 4 | | 2003 | 1 | 5 | 6 | | 2002 | 1 | 1 | 2 | | 2001 | 0 | 3 | 3 | | 2000 | 1 | 3 | 4 | | 1999 | 0 | 1 | 1 | | 1998 | 1 | 3 | 4 | | 1997 | 0 | 4 | 4 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "JNK Mitogen-Activated Protein Kinases" by people in Profiles over the past ten years.
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Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells. Nat Immunol. 2022 01; 23(1):62-74.
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Hu J, Ramshesh VK, McGill MR, Jaeschke H, Lemasters JJ. Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver. Toxicol Sci. 2016 Mar; 150(1):204-15.
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Xie Y, McGill MR, Du K, Dorko K, Kumer SC, Schmitt TM, Ding WX, Jaeschke H. Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes. Toxicol Appl Pharmacol. 2015 Dec 01; 289(2):213-22.
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Woolbright BL, McGill MR, Yan H, Jaeschke H. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes. Basic Clin Pharmacol Toxicol. 2016 Feb; 118(2):160-7.
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Du K, Xie Y, McGill MR, Jaeschke H. Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity. Expert Opin Drug Metab Toxicol. 2015; 11(11):1769-79.
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Guldiken N, Zhou Q, Kucukoglu O, Rehm M, Levada K, Gross A, Kwan R, James LP, Trautwein C, Omary MB, Strnad P. Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation. Hepatology. 2015 Sep; 62(3):876-86.
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Chang WC, Wu SL, Huang WC, Hsu JY, Chan SH, Wang JM, Tsai JP, Chen BK. PTX3 gene activation in EGF-induced head and neck cancer cell metastasis. Oncotarget. 2015 Apr 10; 6(10):7741-57.
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Du K, McGill MR, Xie Y, Bajt ML, Jaeschke H. Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity. Food Chem Toxicol. 2015 Jul; 81:62-70.
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