 Vascular Endothelial Growth Factor A
"Vascular Endothelial Growth Factor A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
| Descriptor ID |
D042461
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| MeSH Number(s) |
D12.644.276.100.800.200 D12.776.467.100.800.200 D23.529.100.800.200
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| Concept/Terms |
Vascular Endothelial Growth Factor A- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factor-A
- Vascular Permeability Factor
- Permeability Factor, Vascular
- VEGF
- VEGF-A
- Vascular Endothelial Growth Factor
- Vasculotropin
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor A".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor A".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor A" by people in UAMS Profiles by year, and whether "Vascular Endothelial Growth Factor A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2023 | 1 | 2 | 3 | | 2022 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 | | 2020 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 0 | 3 | 3 | | 2016 | 0 | 3 | 3 | | 2015 | 0 | 3 | 3 | | 2014 | 0 | 4 | 4 | | 2013 | 0 | 4 | 4 | | 2012 | 1 | 4 | 5 | | 2011 | 2 | 3 | 5 | | 2010 | 2 | 3 | 5 | | 2009 | 3 | 4 | 7 | | 2008 | 1 | 1 | 2 | | 2007 | 1 | 2 | 3 | | 2006 | 3 | 3 | 6 | | 2005 | 1 | 3 | 4 | | 2004 | 3 | 3 | 6 | | 2003 | 0 | 2 | 2 | | 2002 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor A" by people in Profiles over the past ten years.
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Zhang JY, Xiao J, Xie B, Barba H, Boachie-Mensah M, Shah RN, Nadeem U, Spedale M, Dylla N, Lin H, Sidebottom AM, D'Souza M, Theriault B, Sulakhe D, Chang EB, Skondra D. Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis. Invest Ophthalmol Vis Sci. 2023 Dec 01; 64(15):21.
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Gulati S, Hsu CY, Shah S, Shah PK, Zon R, Alsamarai S, Awosika J, El-Bakouny Z, Bashir B, Beeghly A, Berg S, de-la-Rosa-Martinez D, Doroshow DB, Egan PC, Fein J, Flora DB, Friese CR, Fromowitz A, Griffiths EA, Hwang C, Jani C, Joshi M, Khan H, Klein EJ, Heater NK, Koshkin VS, Kwon DH, Labaki C, Latif T, McKay RR, Nagaraj G, Nakasone ES, Nonato T, Polimera HV, Puc M, Razavi P, Ruiz-Garcia E, Saliby RM, Shastri A, Singh SRK, Tagalakis V, Vilar-Compte D, Weissmann LB, Wilkins CR, Wise-Draper TM, Wotman MT, Yoon JJ, Mishra S, Grivas P, Shyr Y, Warner JL, Connors JM, Shah DP, Rosovsky RP. Systemic Anticancer Therapy and Thromboembolic Outcomes in Hospitalized Patients With Cancer and COVID-19. JAMA Oncol. 2023 10 01; 9(10):1390-1400.
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Choubey M, Bora P. Emerging Role of Adiponectin/AdipoRs Signaling in Choroidal Neovascularization, Age-Related Macular Degeneration, and Diabetic Retinopathy. Biomolecules. 2023 06 13; 13(6).
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Saba NF, Steuer CE, Ekpenyong A, McCook-Veal A, Magliocca K, Patel M, Schmitt NC, Stokes W, Bates JE, Rudra S, Remick J, McDonald M, Abousaud M, Tan AC, Fadlullah MZH, Chaudhary R, Muzaffar J, Kirtane K, Liu Y, Chen GZ, Shin DM, Teng Y, Chung CH. Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial. Nat Med. 2023 04; 29(4):880-887.
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ElSheikh RH, Chauhan MZ, Sallam AB. Current and Novel Therapeutic Approaches for Treatment of Neovascular Age-Related Macular Degeneration. Biomolecules. 2022 11 03; 12(11).
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Paulissen E, Martin BL. Myogenic regulatory factors Myod and Myf5 are required for dorsal aorta formation and angiogenic sprouting. Dev Biol. 2022 10; 490:134-143.
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Movahedan A, Barba H, Spedale M, Deng N, Arvans D, Nadeem U, Leone V, Chang EB, Theriault B, Skondra D. Gnotobiotic Operations and Assembly for Development of Germ-Free Animal Model of Laser-Induced Choroidal Neovascularization. Transl Vis Sci Technol. 2021 08 02; 10(9):14.
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Song KM, Kim WJ, Choi MJ, Kwon KD, Limanjaya A, Ghatak K, Ock J, Yin GN, Sato Y, Hong SS, Ryu JK, Suh JK. Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice. Sci Rep. 2021 01 13; 11(1):1114.
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Kilgore DA, Behrens AW, Siddiqui MZ, Chancellor JR, Phillips PH, Uwaydat SH, Vonlanthen MG, Gonzalez-Krellwitz L, Sallam AB. Inflammatory choroiditis and papillitis from Crohn's disease in a child. J AAPOS. 2021 02; 25(1):37-40.
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Mulcrone PL, Edwards SKE, Petrusca DN, Haneline LS, Delgado-Calle J, Roodman GD. Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23. Sci Rep. 2020 10 14; 10(1):17319.
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Singh SR, Fung AT, Fraser-Bell S, Lupidi M, Mohan S, Gabrielle PH, Zur D, Iglicki M, M L?pez-Corell P, Gallego-Pinazo R, Farinha C, Lima LH, Mansour AM, Casella AM, Wu L, Silva R, Uwaydat SH, Govindahari V, Arevalo JF, Chhablani J. One-year outcomes of anti-vascular endothelial growth factor therapy in peripapillary choroidal neovascularisation. Br J Ophthalmol. 2020 05; 104(5):678-683.
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Skar GL, Synhorst D, Beaver M, Snowden JN. CSF inflammatory markers differ in gram-positive versus gram-negative shunt infections. J Neuroinflammation. 2019 Jan 09; 16(1):7.
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Zhao H, Cai H, Wang C, Huang XF, Cao XX, Zhang L, Zhou DB, Li J. Prognostic value of serum vascular endothelial growth factor and hematological responses in patients with newly-diagnosed POEMS syndrome. Blood Cancer J. 2018 04 04; 8(4):37.
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Kim SR, Eirin A, Herrmann SMS, Saad A, Juncos LA, Lerman A, Textor SC, Lerman LO. Preserved endothelial progenitor cell angiogenic activity in African American essential hypertensive patients. Nephrol Dial Transplant. 2018 03 01; 33(3):392-401.
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Singh A, Bora P, Krishna A. Systemic adiponectin treatment reverses polycystic ovary syndrome-like features in an animal model. Reprod Fertil Dev. 2018 Mar; 30(4):571-584.
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Yang W, Yaggie RE, Jiang MC, Rudick CN, Done J, Heckman CJ, Rosen JM, Schaeffer AJ, Klumpp DJ. Acyloxyacyl hydrolase modulates pelvic pain severity. Am J Physiol Regul Integr Comp Physiol. 2018 03 01; 314(3):R353-R365.
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Bais C, Mueller B, Brady MF, Mannel RS, Burger RA, Wei W, Marien KM, Kockx MM, Husain A, Birrer MJ. Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses. J Natl Cancer Inst. 2017 11 01; 109(11).
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Zhang X, Cai QQ, Huang XF, Cao XX, Cai H, Zhou DB, Dai RP, Li J. OCULAR MANIFESTATIONS AND TREATMENT OUTCOMES IN CHINESE PATIENTS WITH POEMS SYNDROME. Retina. 2017 Sep; 37(9):1784-1791.
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Reina-Torres E, Wen JC, Liu KC, Li G, Sherwood JM, Chang JY, Challa P, Fl?gel-Koch CM, Stamer WD, Allingham RR, Overby DR. VEGF as a Paracrine Regulator of Conventional Outflow Facility. Invest Ophthalmol Vis Sci. 2017 03 01; 58(3):1899-1908.
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Sinha S, Khan S, Shukla S, Lakra AD, Kumar S, Das G, Maurya R, Meeran SM. Cucurbitacin B inhibits breast cancer metastasis and angiogenesis through VEGF-mediated suppression of FAK/MMP-9 signaling axis. Int J Biochem Cell Biol. 2016 08; 77(Pt A):41-56.
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Divine LM, Kizer NT, Hagemann AR, Pittman ME, Chen L, Powell MA, Mutch DG, Rader JS, Thaker PH. Clinicopathologic characteristics and survival of patients with gynecologic malignancies metastatic to the brain. Gynecol Oncol. 2016 07; 142(1):76-82.
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Goyal S, Lyzogubov VV, Ali O, Bora PS, Bora NS, Uwaydat SH. Effect of aspirin on models of retinal pigment epithelium pathology. Clin Exp Ophthalmol. 2016 Sep; 44(7):610-617.
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Yeruva L, Spencer NE, Saraf MK, Hennings L, Bowlin AK, Cleves MA, Mercer K, Chintapalli SV, Shankar K, Rank RG, Badger TM, Ronis MJ. Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model. BMC Gastroenterol. 2016 Mar 22; 16:40.
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Morshedi RG, Ricca AM, Wirostko BM. Ocular Hypertension Following Intravitreal Antivascular Endothelial Growth Factor Therapy: Review of the Literature and Possible Role of Nitric Oxide. J Glaucoma. 2016 Mar; 25(3):291-300.
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Ulrich F, Carretero-Ortega J, Men?ndez J, Narvaez C, Sun B, Lancaster E, Pershad V, Trzaska S, V?liz E, Kamei M, Prendergast A, Kidd KR, Shaw KM, Castranova DA, Pham VN, Lo BD, Martin BL, Raible DW, Weinstein BM, Torres-V?zquez J. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development. 2016 Jan 01; 143(1):147-59.
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