 Lipopolysaccharides
"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
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| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in UAMS Profiles by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 2 | 0 | 2 | | 2023 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 2 | 3 | | 2020 | 2 | 1 | 3 | | 2019 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 | | 2017 | 0 | 1 | 1 | | 2016 | 2 | 2 | 4 | | 2015 | 1 | 5 | 6 | | 2014 | 2 | 4 | 6 | | 2013 | 2 | 3 | 5 | | 2012 | 1 | 6 | 7 | | 2011 | 0 | 5 | 5 | | 2010 | 0 | 5 | 5 | | 2009 | 2 | 3 | 5 | | 2008 | 2 | 4 | 6 | | 2007 | 0 | 5 | 5 | | 2006 | 5 | 2 | 7 | | 2005 | 1 | 6 | 7 | | 2004 | 1 | 6 | 7 | | 2003 | 2 | 7 | 9 | | 2002 | 0 | 4 | 4 | | 2001 | 3 | 3 | 6 | | 2000 | 1 | 4 | 5 | | 1999 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 1997 | 1 | 1 | 2 | | 1996 | 0 | 3 | 3 | | 1995 | 0 | 2 | 2 | | 1994 | 1 | 1 | 2 | | 1992 | 1 | 2 | 3 | | 1991 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles over the past ten years.
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Li W, Hakkak R. Soy Protein Concentrate Diets Inversely Affect LPS-Binding Protein Expression in Colon and Liver, Reduce Liver Inflammation, and Increase Fecal LPS Excretion in Obese Zucker Rats. Nutrients. 2024 Mar 28; 16(7).
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Verma A, Azhar G, Patyal P, Zhang W, Zhang X, Wei JY. Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells. Geroscience. 2024 Oct; 46(5):4315-4332.
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Banker RS, Rippy MK, Cooper N, Neu?il P, Exner DV, Nair DG, Booth DF, Ligon D, Badie N, Krans M, Ando K, Knops RE, Ip JE, Doshi RN, Rashtian M, Reddy VY. Retrieval of Chronically Implanted Dual-chamber Leadless Pacemakers in an Ovine Model. Circ Arrhythm Electrophysiol. 2023 10; 16(10):e012232.
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Mittal E, Cupp G, Kang YA. Simulating the Effect of Gut Microbiome on Cancer Cell Growth Using a Microfluidic Device. Sensors (Basel). 2023 Jan 22; 23(3).
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Verma A, Azhar G, Zhang X, Patyal P, Kc G, Sharma S, Che Y, Wei JY. P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress. Int J Mol Sci. 2023 Jan 04; 24(2).
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Lin CC, Chang TY, Lu YC, Wu YS, Huang W, Lo WC, Liu GF, Hsu WC, Ohashi PS, Mak TW, Fuh JL, Chen HC, Tarng DC, Chen NJ. TREM-2 mediates dendritic cell-induced NO to suppress Th17 activation and ameliorate chronic kidney diseases. J Mol Med (Berl). 2022 06; 100(6):917-931.
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Yang FM, Chang HM, Yeh ETH. Regulation of TLR4 signaling through the TRAF6/sNASP axis by reversible phosphorylation mediated by CK2 and PP4. Proc Natl Acad Sci U S A. 2021 11 23; 118(47).
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Alshehri S, Imam SS. Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects. Biomolecules. 2021 11 23; 11(12).
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Kim TH, Heo SY, Oh GW, Park WS, Choi IW, Kang HW, Kim HW, Kim YM, Jo SH, Park SH, Jung WK. A phlorotannins-loaded homogeneous acellular matrix film modulates post-implantation inflammatory responses. J Tissue Eng Regen Med. 2022 01; 16(1):51-62.
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Budamagunta V, Manohar-Sindhu S, Yang Y, He Y, Traktuev DO, Foster TC, Zhou D. Senescence-associated hyper-activation to inflammatory stimuli in vitro. Aging (Albany NY). 2021 08 10; 13(15):19088-19107.
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Najjar RS, Akhavan NS, Pourafshar S, Arjmandi BH, Feresin RG. Cornus officinalis var. koreana Kitam polyphenol extract decreases pro-inflammatory markers in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages by reducing Akt phosphorylation. J Ethnopharmacol. 2021 Apr 24; 270:113734.
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Oh C, Verma A, Aachoui Y. Caspase-11 Non-canonical Inflammasomes in the Lung. Front Immunol. 2020; 11:1895.
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Leeds J, Scindia Y, Loi V, Wlazlo E, Ghias E, Cechova S, Portilla D, Ledesma J, Swaminathan S. Protective role of DJ-1 in endotoxin-induced acute kidney injury. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F654-F663.
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Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2019 12 17; 9(1):19276.
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Lee SM, Carlson AH, Onal M, Benkusky NA, Meyer MB, Pike JW. A Control Region Near the Fibroblast Growth Factor 23 Gene Mediates Response to Phosphate, 1,25(OH)2D3, and LPS In Vivo. Endocrinology. 2019 12 01; 160(12):2877-2891.
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Wu C, Lu W, Zhang Y, Zhang G, Shi X, Hisada Y, Grover SP, Zhang X, Li L, Xiang B, Shi J, Li XA, Daugherty A, Smyth SS, Kirchhofer D, Shiroishi T, Shao F, Mackman N, Wei Y, Li Z. Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. Immunity. 2019 06 18; 50(6):1401-1411.e4.
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Moon SH, Huang E. Novel linear lipopeptide paenipeptin C' binds to lipopolysaccharides and lipoteichoic acid and exerts bactericidal activity by the disruption of cytoplasmic membrane. BMC Microbiol. 2019 01 08; 19(1):6.
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Lionikaite V, Westerlund A, Conaway HH, Henning P, Lerner UH. Effects of retinoids on physiologic and inflammatory osteoclastogenesis in vitro. J Leukoc Biol. 2018 12; 104(6):1133-1145.
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Rosen JM, Yaggie RE, Woida PJ, Miller RJ, Schaeffer AJ, Klumpp DJ. TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain. Sci Rep. 2018 05 08; 8(1):7188.
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Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J. DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages. J Biol Chem. 2018 03 16; 293(11):3965-3980.
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Casero D, Gill K, Sridharan V, Koturbash I, Nelson G, Hauer-Jensen M, Boerma M, Braun J, Cheema AK. Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome. Microbiome. 2017 08 18; 5(1):105.
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Jorgenson MA, Young KD. Interrupting Biosynthesis of O Antigen or the Lipopolysaccharide Core Produces Morphological Defects in Escherichia coli by Sequestering Undecaprenyl Phosphate. J Bacteriol. 2016 11 15; 198(22):3070-3079.
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Ni HM, McGill MR, Chao X, Woolbright BL, Jaeschke H, Ding WX. Caspase Inhibition Prevents Tumor Necrosis Factor-a-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in?Vivo and in?Vitro. Am J Pathol. 2016 10; 186(10):2623-36.
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Ding Z, Liu S, Wang X, Mathur P, Dai Y, Theus S, Deng X, Fan Y, Mehta JL. Cross-Talk Between PCSK9 and Damaged mtDNA in Vascular Smooth Muscle Cells: Role in Apoptosis. Antioxid Redox Signal. 2016 12 20; 25(18):997-1008.
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Qin B, Wei T, Wang L, Ma N, Tang Q, Liang Y, Yang Z, Zhou L, Zhong R. Decreased expression of TIPE2 contributes to the hyperreactivity of monocyte to Toll-like receptor ligands in primary biliary cirrhosis. J Gastroenterol Hepatol. 2016 Jun; 31(6):1177-83.
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Peters AL, Beuger B, Mock DM, Widness JA, de Korte D, Juffermans NP, Vlaar AP, van Bruggen R. Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model. Transfusion. 2016 06; 56(6):1362-9.
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Ryu S, Johnson A, Park Y, Kim B, Norris D, Armstrong CA, Song PI. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes. PLoS One. 2015; 10(8):e0136887.
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Ryu S, Han HM, Song PI, Armstrong CA, Park Y. Suppression of Propionibacterium acnes Infection and the Associated Inflammatory Response by the Antimicrobial Peptide P5 in Mice. PLoS One. 2015; 10(7):e0132619.
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Ding Z, Liu S, Wang X, Deng X, Fan Y, Shahanawaz J, Shmookler Reis RJ, Varughese KI, Sawamura T, Mehta JL. Cross-talk between LOX-1 and PCSK9 in vascular tissues. Cardiovasc Res. 2015 Sep 01; 107(4):556-67.
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Onal M, Bishop KA, St John HC, Danielson AL, Riley EM, Piemontese M, Xiong J, Goellner JJ, O'Brien CA, Pike JW. A DNA segment spanning the mouse Tnfsf11 transcription unit and its upstream regulatory domain rescues the pleiotropic biologic phenotype of the RANKL null mouse. J Bone Miner Res. 2015 May; 30(5):855-68.
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Cieniewicz B, Dong Q, Li G, Forrest JC, Mounce BC, Tarakanova VL, van der Velden A, Krug LT. Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1? Production upon Extrinsic Stimulation in Culture. J Virol. 2015 Jul; 89(13):6562-74.
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Ding Z, Liu S, Wang X, Deng X, Fan Y, Sun C, Wang Y, Mehta JL. Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta. Antioxid Redox Signal. 2015 Mar 20; 22(9):760-71.
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