| Item Type | Name |
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Academic Article
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Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines.
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Academic Article
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Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients.
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Academic Article
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Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.
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Academic Article
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Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.
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Academic Article
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NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
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Academic Article
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Mechanisms of thrombosis in paraproteinemias: the effects of immunomodulatory drugs.
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Academic Article
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Survival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasone.
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Academic Article
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Impact of bortezomib on bone health in myeloma: a review of current evidence.
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Academic Article
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RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.
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Concept
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Adenine
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Concept
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Acetylcysteine
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Concept
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Boronic Acids
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Concept
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Antigens, Neoplasm
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Concept
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Antineoplastic Agents
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Concept
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Bacterial Proteins
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Concept
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Benzamides
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Concept
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Cyclopentanes
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Concept
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Dexamethasone
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Concept
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Deoxyglucose
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Concept
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Antibodies
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Concept
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Drug Tolerance
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Concept
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Disulfiram
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Concept
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Drug Evaluation, Preclinical
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Concept
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Alkaline Phosphatase
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Concept
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Antigens, Differentiation
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Concept
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Anticoagulants
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Concept
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Epitopes
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Concept
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Antibodies, Monoclonal
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Concept
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Arsenicals
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Concept
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Antigens, Differentiation, T-Lymphocyte
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Concept
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Glutathione Peroxidase
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Concept
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Aldehyde Dehydrogenase
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Concept
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Calcium-Binding Proteins
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Concept
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Azacitidine
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Concept
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Ascorbic Acid
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Concept
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Microtubule-Associated Proteins
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Concept
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Hydrogen Peroxide
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Concept
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Dose-Response Relationship, Drug
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Concept
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Carrier Proteins
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Concept
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Cyclophosphamide
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Concept
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Histone Deacetylases
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Concept
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HLA Antigens
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Concept
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Base Sequence
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Concept
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Hippurates
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Concept
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Doxorubicin
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Concept
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Drug Resistance
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Concept
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Enzyme Inhibitors
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Concept
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Transcription Factors
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Concept
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DNA-Binding Proteins
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Concept
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Drug Synergism
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Concept
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Interferon-gamma
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Concept
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Receptors, IgG
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Concept
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Protein Kinases
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Concept
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Pyrimidines
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Concept
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Receptors, Glucocorticoid
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Concept
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Membrane Proteins
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Concept
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Membrane Glycoproteins
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Concept
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Sulfones
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Concept
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Plasmids
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Concept
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Receptors, Interleukin-6
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Concept
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Caspases
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Concept
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Glycoproteins
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Concept
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Protein C
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Concept
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Histocompatibility Antigens Class I
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Concept
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Protein-Tyrosine Kinases
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Concept
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Pyruvate Kinase
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Concept
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Receptors, Immunologic
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Concept
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Organophosphorus Compounds
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Concept
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Vincristine
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Concept
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Microfilament Proteins
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Concept
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Polysaccharides
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Concept
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Interleukin-6
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Concept
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Oxidants
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Concept
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Prednisone
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Concept
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Proteins
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Concept
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Superoxide Dismutase
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Concept
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RNA, Small Interfering
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|
Concept
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CDC2-CDC28 Kinases
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Concept
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Gelatinases
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Concept
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Receptors, Retinoic Acid
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Concept
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CDC2 Protein Kinase
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Concept
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Polysaccharide-Lyases
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Concept
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Proto-Oncogene Proteins
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Concept
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Receptors, Transferrin
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Concept
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Pyrazines
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Concept
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Receptors, Cell Surface
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Concept
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Repressor Proteins
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Concept
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Oncogene Proteins
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Concept
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Cell Adhesion Molecules
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Concept
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Antigens, CD19
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Concept
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Antigens, CD20
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Concept
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Recombinant Proteins
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Concept
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Ribosomal Proteins
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Concept
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Cation Transport Proteins
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Concept
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rab GTP-Binding Proteins
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Concept
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Ubiquitins
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Concept
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TNF-Related Apoptosis-Inducing Ligand
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Concept
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Veratrum Alkaloids
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Concept
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ADP-ribosyl Cyclase
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Concept
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Cancer Vaccines
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|
Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Early Growth Response Protein 1
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Concept
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NF-kappa B p52 Subunit
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Concept
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Inhibitor of Apoptosis Proteins
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Concept
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Janus Kinase 1
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Concept
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RANK Ligand
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Concept
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Antineoplastic Agents, Hormonal
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Concept
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Cyclin D
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Concept
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Cyclin B
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Concept
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3' Untranslated Regions
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Concept
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Hydrocortisone
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Concept
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Hydroxamic Acids
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Concept
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Glutathione
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Concept
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Parathyroid Hormone
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Concept
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Proteoglycans
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Concept
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Integrin beta Chains
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Concept
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MAP Kinase Kinase 1
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Concept
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DNA
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Concept
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Drug Interactions
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Concept
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Melphalan
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Concept
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Piperazines
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Concept
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HLA-A Antigens
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Concept
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Oligonucleotide Probes
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Concept
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NF-kappa B
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Concept
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Angiogenesis Inhibitors
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Concept
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RNA, Messenger
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Concept
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Proto-Oncogene Proteins c-jun
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Concept
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Syndecans
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Concept
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Tumor Suppressor Protein p53
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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DNA, Neoplasm
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Concept
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Ubiquitin-Protein Ligases
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Concept
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Multidrug Resistance-Associated Proteins
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Interferon Regulatory Factor-1
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Concept
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DNA Primers
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|
Concept
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Onium Compounds
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Concept
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Cyclin-Dependent Kinase Inhibitor p21
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Concept
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bcl-X Protein
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Concept
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Wnt Proteins
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Concept
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Receptors, TNF-Related Apoptosis-Inducing Ligand
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Concept
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Glucose
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Concept
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Small Molecule Libraries
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Concept
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Maf Transcription Factors, Large
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|
Concept
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Vidarabine
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Concept
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NM23 Nucleoside Diphosphate Kinases
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Concept
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Phenylpropionates
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|
Concept
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Antigens, CD
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|
Concept
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11-beta-Hydroxysteroid Dehydrogenase Type 2
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|
Concept
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Itraconazole
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Concept
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Antibodies, Bispecific
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Concept
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Drug Therapy, Combination
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|
Concept
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Cyclin-Dependent Kinases
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Concept
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DNA, Single-Stranded
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|
Concept
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Drug Discovery
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|
Concept
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Ferritins
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|
Concept
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Glucuronidase
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|
Concept
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Heterogeneous-Nuclear Ribonucleoprotein Group A-B
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Concept
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NAD+ Nucleosidase
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|
Concept
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Lactate Dehydrogenases
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|
Concept
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JNK Mitogen-Activated Protein Kinases
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|
Concept
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Extracellular Signal-Regulated MAP Kinases
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|
Concept
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Glucocorticoids
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|
Concept
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I-kappa B Kinase
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|
Concept
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STAT Transcription Factors
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|
Concept
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Ligands
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|
Concept
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Immunologic Factors
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Concept
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Iron
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|
Concept
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Isoxazoles
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|
Concept
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Melanoma-Specific Antigens
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|
Concept
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Antibodies, Monoclonal, Humanized
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|
Concept
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Proteasome Inhibitors
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|
Concept
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Heat-Shock Proteins
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Concept
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TNF Receptor-Associated Factor 3
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Concept
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Mitoxantrone
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Concept
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Oligopeptides
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|
Concept
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Thyroid Hormones
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Concept
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Thalidomide
|
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Concept
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Endopeptidases
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Concept
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Piperidines
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|
Concept
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Pyrazoles
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|
Concept
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Protease Inhibitors
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Concept
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Pyridines
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Concept
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Peptide Library
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Concept
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RNA, Neoplasm
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|
Concept
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Extracellular Matrix Proteins
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Concept
|
ras Proteins
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Concept
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Tumor Suppressor Proteins
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Concept
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Cysteine Proteinase Inhibitors
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|
Concept
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Receptors, Estrogen
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|
Concept
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Viper Venoms
|
|
Concept
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Cell Cycle Proteins
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|
Concept
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Protein Phosphatase 2
|
|
Concept
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Protein Tyrosine Phosphatases
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|
Concept
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Reactive Oxygen Species
|
|
Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Receptors, G-Protein-Coupled
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Concept
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Apoptosis
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Concept
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Tretinoin
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Concept
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Cyclin D1
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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HLA-A2 Antigen
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Concept
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Enzyme Activators
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Concept
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Drug Resistance, Neoplasm
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Concept
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Retinal Dehydrogenase
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Concept
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STAT3 Transcription Factor
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Concept
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Protein Kinase Inhibitors
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Concept
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Cyclins
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Concept
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Polycomb Repressive Complex 2
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Concept
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NF-E2-Related Factor 2
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Concept
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Chromatin
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Concept
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Diphosphonates
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Concept
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Drug Screening Assays, Antitumor
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Concept
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Intercellular Adhesion Molecule-1
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Concept
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Histone Deacetylase Inhibitors
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Concept
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RNA, Complementary
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Concept
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Zebrafish Proteins
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Concept
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Nuclear Factor 90 Proteins
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Concept
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Core Binding Factor Alpha 1 Subunit
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Concept
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beta Catenin
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Concept
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Caspase 3
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Concept
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Neoplasm Proteins
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Concept
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Oxides
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Concept
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B-Cell Maturation Antigen
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Concept
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Lectins, C-Type
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Cyclin-Dependent Kinase Inhibitor p27
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Concept
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Inflammasomes
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Concept
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S-Phase Kinase-Associated Proteins
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Concept
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Proteasome Endopeptidase Complex
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Concept
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Forkhead Transcription Factors
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Concept
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Hedgehog Proteins
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|
Concept
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Cyclin D3
|
|
Concept
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Cyclin D2
|
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Concept
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Syndecan-1
|
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Concept
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TOR Serine-Threonine Kinases
|
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Concept
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Antibodies, Monoclonal, Murine-Derived
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Concept
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Factor V
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Concept
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Peptides
|
|
Concept
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Immunoglobulins
|
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Concept
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Serine Endopeptidases
|
|
Concept
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Protein Isoforms
|
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Concept
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MicroRNAs
|
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Concept
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Bone Density Conservation Agents
|
|
Concept
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Proto-Oncogene Proteins c-akt
|
|
Concept
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Integrins
|
|
Concept
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Cytokines
|
|
Concept
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p38 Mitogen-Activated Protein Kinases
|
|
Concept
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Scavenger Receptors, Class A
|
|
Concept
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NF-kappa B p50 Subunit
|
|
Concept
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Cystatin M
|
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Academic Article
|
Drug resistance in hematologic malignancies: induction mechanisms, genetics, and therapeutics.
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Academic Article
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Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.
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Academic Article
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Inhibition of Nek2 by small molecules affects proteasome activity.
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Academic Article
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Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma.
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Academic Article
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Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
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Academic Article
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Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.
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Academic Article
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Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic Acid.
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Academic Article
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Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma.
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Academic Article
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NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma.
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Academic Article
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Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma.
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Academic Article
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NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
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|
Academic Article
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Identification and Characterization of Tumor-Initiating Cells in Multiple Myeloma.
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|
Academic Article
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Carfilzomib enhances natural killer cell-mediated lysis of myeloma linked with decreasing expression of HLA class I.
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Academic Article
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TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
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Academic Article
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Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model.
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Academic Article
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Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma.
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Academic Article
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Down-regulation of 11?-hydroxysteroid dehydrogenase type 2 by bortezomib sensitizes Jurkat leukemia T cells against glucocorticoid-induced apoptosis.
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Academic Article
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Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3.
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Academic Article
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Correction to: Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma.
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Academic Article
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Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.
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Academic Article
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Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells.
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Academic Article
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Copper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma.
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Academic Article
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Proteasome inhibitor carfilzomib interacts synergistically with histone deacetylase inhibitor vorinostat in Jurkat T-leukemia cells.
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Academic Article
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NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
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Academic Article
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Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a.
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Grant
|
Retinoid Based Treatment Approaches to Target the Myeloma Stem Cell
|
|
Grant
|
NEK2 Over-expression Causes Drug Resistance in Myeloma
|
|
Academic Article
|
Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents.
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Academic Article
|
RFWD2 induces cellular proliferation and selective proteasome inhibitor resistance by mediating P27 ubiquitination in multiple myeloma.
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Academic Article
|
GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.
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|
Grant
|
Targeting NEK2 Enables Immune Checkpoint Blockade in High-Risk/Relapsed Myeloma
|
|
Academic Article
|
Role of NEK2A in human cancer and its therapeutic potentials.
|