 I-kappa B Kinase
"I-kappa B Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.
| Descriptor ID |
D051550
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| MeSH Number(s) |
D08.811.913.696.620.682.700.494 D12.644.360.376 D12.776.476.378
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| Concept/Terms |
I-kappa B Kinase- I-kappa B Kinase
- B Kinase, I-kappa
- Kinase, I-kappa B
- IkappaB Kinase
- Kinase, IkappaB
- NK-kappa B-Activating Kinase NAK
- NK kappa B Activating Kinase NAK
- I kappa B Kinase
IkappaB Kinase gamma- IkappaB Kinase gamma
- NF-kappaB Essential Modifier
- Essential Modifier, NF-kappaB
- NF kappaB Essential Modifier
- IKK gamma
IkappaB Kinase alpha- IkappaB Kinase alpha
- Kinase alpha, IkappaB
- Conserved Helix-Loop-Helix Ubiquitous Kinase
- Conserved Helix Loop Helix Ubiquitous Kinase
- IKK alpha
- IkappaBalpha Kinase
- IKK 1 Kinase
- CHUK Kinase
- I Kappa B alpha-Associated Protein Kinase
- I Kappa B alpha Associated Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "I-kappa B Kinase".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Kinase".
This graph shows the total number of publications written about "I-kappa B Kinase" by people in UAMS Profiles by year, and whether "I-kappa B Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 2 | 3 | | 2010 | 1 | 2 | 3 | | 2007 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "I-kappa B Kinase" by people in Profiles over the past ten years.
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McCorkell KA, Jayachandran N, Cully MD, Freund-Brown J, Weinkopff T, Monslow J, Hu Y, Pur? E, Freedman BD, Alvarez JI, Cancro MP, May MJ. Lymph node formation and B cell homeostasis require IKK-a in distinct endothelial cell-derived compartments. Proc Natl Acad Sci U S A. 2021 11 30; 118(48).
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Liu M, Chen S, Yueh MF, Fujiwara R, Konopnicki C, Hao H, Tukey RH. Cadmium and arsenic override NF-?B developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia. Biochem Pharmacol. 2016 06 15; 110-111:37-46.
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Mao X, Phanavanh B, Hamdan H, Moerman-Herzog AM, Barger SW. NF?B-inducing kinase inhibits NF?B activity specifically in neurons of the CNS. J Neurochem. 2016 Apr; 137(2):154-63.
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Cullen S, Ponnappan S, Ponnappan U. Redox-regulated pathway of tyrosine phosphorylation underlies NF-?B induction by an atypical pathway independent of the 26S proteasome. Biomolecules. 2015 Feb 09; 5(1):95-112.
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Fowler TW, Kamalakar A, Akel NS, Kurten RC, Suva LJ, Gaddy D. Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures. J Cell Sci. 2015 Feb 15; 128(4):683-94.
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