 Receptors, G-Protein-Coupled
"Receptors, G-Protein-Coupled" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
| Descriptor ID |
D043562
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| MeSH Number(s) |
D12.776.543.750.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, G-Protein-Coupled".
Below are MeSH descriptors whose meaning is more specific than "Receptors, G-Protein-Coupled".
- Receptors, G-Protein-Coupled
- Calcitonin Receptor-Like Protein
- Frizzled Receptors
- Receptor, Anaphylatoxin C5a
- Receptor, PAR-2
- Receptors, Adrenomedullin
- Receptors, Angiotensin
- Receptors, Bombesin
- Receptors, Bradykinin
- Receptors, Calcitonin
- Receptors, Calcitonin Gene-Related Peptide
- Receptors, Calcium-Sensing
- Receptors, Cannabinoid
- Receptors, Catecholamine
- Receptors, Chemokine
- Receptors, Cholecystokinin
- Receptors, Corticotropin-Releasing Hormone
- Receptors, Eicosanoid
- Receptors, Endothelin
- Receptors, Formyl Peptide
- Receptors, FSH
- Receptors, GABA-B
- Receptors, Galanin
- Receptors, Ghrelin
- Receptors, Glucagon
- Receptors, Histamine H1
- Receptors, Histamine H2
- Receptors, Islet Amyloid Polypeptide
- Receptors, LH
- Receptors, LHRH
- Receptors, Lysophospholipid
- Receptors, Melanocortin
- Receptors, Melatonin
- Receptors, Metabotropic Glutamate
- Receptors, Muscarinic
- Receptors, Neuropeptide Y
- Receptors, Neurotensin
- Receptors, Odorant
- Receptors, Opioid
- Receptors, Oxytocin
- Receptors, Parathyroid Hormone
- Receptors, Pheromone
- Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide
- Receptors, Purinergic
- Receptors, Serotonin
- Receptors, Somatostatin
- Receptors, Thrombin
- Receptors, Vasoactive Intestinal Peptide
- Receptors, Vasopressin
- Rhodopsin
This graph shows the total number of publications written about "Receptors, G-Protein-Coupled" by people in UAMS Profiles by year, and whether "Receptors, G-Protein-Coupled" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 3 | 4 | | 2022 | 5 | 3 | 8 | | 2021 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2016 | 1 | 2 | 3 | | 2015 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 0 | 3 | 3 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2004 | 1 | 0 | 1 | | 2003 | 2 | 0 | 2 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, G-Protein-Coupled" by people in Profiles over the past ten years.
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Elemian S, Al Hadidi S. Targeting GPRC5D in multiple myeloma. Expert Rev Anticancer Ther. 2024 May; 24(5):229-238.
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Schinke C. The impressive efficacy of anti-G protein-coupled receptor, class C group 5 member D chimeric antigen receptor T cells in patients with relapsed or refractory multiple myeloma. Chin Clin Oncol. 2024 Jun; 13(3):45.
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Hammons L, Szabo A, Janardan A, Bhatlapenumarthi V, Annyapu E, Dhakal B, Al Hadidi S, Radhakrishnan SV, Narra R, Bhutani D, Thanendrarajan S, Janz S, Zangari M, Lentzsch S, Van Rhee F, Crescencio JCR, D'Souza A, Chakraborty R, Mohan M, Schinke C. The changing spectrum of infection with BCMA and GPRC5D targeting bispecific antibody (bsAb) therapy in patients with relapsed refractory multiple myeloma. Haematologica. 2024 03 01; 109(3):906-914.
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Rodriguez-Otero P, van de Donk NWCJ, Pillarisetti K, Cornax I, Vishwamitra D, Gray K, Hilder B, Tolbert J, Renaud T, Masterson T, Heuck C, Kane C, Verona R, Moreau P, Bahlis N, Chari A. GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review. Blood Cancer J. 2024 02 02; 14(1):24.
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Bhandari D, Kachhap S, Madhukar G, Adepu KK, Anishkin A, Chen JR, Chintapalli SV. Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy. Int J Mol Sci. 2022 Nov 26; 23(23).
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Esteban-Lopez M, Wilson KJ, Myhr C, Kaftanovskaya EM, Henderson MJ, Southall NT, Xu X, Wang A, Hu X, Barnaeva E, Ye W, George ER, Sherrill JT, Ferrer M, Morello R, Agoulnik IU, Marugan JJ, Agoulnik AI. Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2. Commun Biol. 2022 11 04; 5(1):1183.
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Mailankody S, Devlin SM, Landa J, Nath K, Diamonte C, Carstens EJ, Russo D, Auclair R, Fitzgerald L, Cadzin B, Wang X, Sikder D, Senechal B, Bermudez VP, Purdon TJ, Hosszu K, McAvoy DP, Farzana T, Mead E, Wilcox JA, Santomasso BD, Shah GL, Shah UA, Korde N, Lesokhin A, Tan CR, Hultcrantz M, Hassoun H, Roshal M, Sen F, Dogan A, Landgren O, Giralt SA, Park JH, Usmani SZ, Rivi?re I, Brentjens RJ, Smith EL. GPRC5D-Targeted CAR T Cells for Myeloma. N Engl J Med. 2022 09 29; 387(13):1196-1206.
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Adepu KK, Kachhap S, Bhandari D, Anishkin A, Chintapalli SV. Computational insights on molecular interactions of acifran with GPR109A and GPR109B. J Mol Model. 2022 Jul 28; 28(8):237.
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Dong X, Limjunyawong N, Sypek EI, Wang G, Ortines RV, Youn C, Alphonse MP, Dikeman D, Wang Y, Lay M, Kothari R, Vasavda C, Pundir P, Goff L, Miller LS, Lu W, Garza LA, Kim BS, Archer NK, Dong X. Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 09 13; 55(9):1645-1662.e7.
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Xue Y, Lyu C, Taylor A, Van Ee A, Kiemen A, Choi Y, Khavanian N, Henn D, Lee C, Hwang L, Wier E, Wang S, Lee S, Li A, Kirby C, Wang G, Wu PH, Wirtz D, Garza LA, Reddy SK. Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth. Sci Adv. 2022 04 29; 8(17):eabl8698.
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Chen JR, Lazarenko OP, Blackburn ML. GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice. Bone. 2022 08; 161:116422.
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Babaahmadi-Rezaei H, Rezaei M, Ghaderi-Zefrehi H, Azizi M, Beheshti-Nasab H, Mehta JL. Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis. Endocr Metab Immune Disord Drug Targets. 2022; 22(12):1191-1200.
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Chen JR, Zhao H, Wankhade UD, Chintapalli SV, Li C, Gai D, Shankar K, Zhan F, Lazarenko OP. GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice. Commun Biol. 2021 01 08; 4(1):53.
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Dibo P, Mara??n RO, Chandrashekar K, Mazzuferi F, Silva GB, Juncos LA, Juncos LI. Angiotensin-(1-7) inhibits sodium transport via Mas receptor by increasing nitric oxide production in thick ascending limb. Physiol Rep. 2019 03; 7(5):e14015.
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Cadirci E, Ugan RA, Dincer B, Gundogdu B, Cinar I, Akpinar E, Halici Z. Urotensin receptors as a new target for CLP induced septic lung injury in mice. Naunyn Schmiedebergs Arch Pharmacol. 2019 02; 392(2):135-145.
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Eggink HM, van Nierop FS, Schooneman MG, Boelen A, Kalsbeek A, Koehorst M, Ten Have GAM, de Brauw LM, Groen AK, Romijn JA, Deutz NEP, Soeters MR. Transhepatic bile acid kinetics in pigs and humans. Clin Nutr. 2018 08; 37(4):1406-1414.
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Lee J, Moraes-Vieira PM, Castoldi A, Aryal P, Yee EU, Vickers C, Parnas O, Donaldson CJ, Saghatelian A, Kahn BB. Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses. J Biol Chem. 2016 Oct 14; 291(42):22207-22217.
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Blossom SJ, Melnyk SB, Li M, Wessinger WD, Cooney CA. Inflammatory and oxidative stress-related effects associated with neurotoxicity are maintained after exclusively prenatal trichloroethylene exposure. Neurotoxicology. 2017 03; 59:164-174.
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Schade GR, Holt SK, Zhang X, Song D, Wright JL, Zhao S, Kolb S, Lam HM, Levin L, Leung YK, Ho SM, Stanford JL. Prostate Cancer Expression Profiles of Cytoplasmic ER?1 and Nuclear ER?2 are Associated with Poor Outcomes following Radical Prostatectomy. J Urol. 2016 06; 195(6):1760-6.
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Mathur P, Ostadal B, Romeo F, Mehta JL. Gender-Related Differences in Atherosclerosis. Cardiovasc Drugs Ther. 2015 Aug; 29(4):319-27.
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