 Diphosphonates
"Diphosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
| Descriptor ID |
D004164
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| MeSH Number(s) |
D02.705.429.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Diphosphonates".
Below are MeSH descriptors whose meaning is more specific than "Diphosphonates".
This graph shows the total number of publications written about "Diphosphonates" by people in UAMS Profiles by year, and whether "Diphosphonates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 | | 2019 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 3 | 0 | 3 | | 2014 | 2 | 0 | 2 | | 2013 | 5 | 1 | 6 | | 2012 | 6 | 2 | 8 | | 2011 | 5 | 1 | 6 | | 2010 | 7 | 2 | 9 | | 2009 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2007 | 3 | 0 | 3 | | 2006 | 3 | 0 | 3 | | 2005 | 2 | 0 | 2 | | 2004 | 1 | 1 | 2 | | 2003 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 1999 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Diphosphonates" by people in Profiles over the past ten years.
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Bellido T. Bisphosphonates for osteoporosis: from bench to clinic. J Clin Invest. 2024 Mar 15; 134(6).
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Bittrich M, Hetterich R, Solimando AG, Krebs M, Loda S, Danhof S, Anton S, Zhou X, Kerscher A, Beilhack A, Kort?m KM, Rasche L, Einsele H, Knop S, Hartmann S. Does medication-related osteonecrosis of the jaw affect survival of patients with Multiple Myeloma?: Exploring a large single center database using artificial intelligence. Clin Exp Med. 2023 Dec; 23(8):5215-5226.
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Yang G, Williams R, Wang L, Farhadfar N, Chen Y, Loiacono AT, Bian J, Holliday LS, Katz J, Gong Y. Medication-Related Osteonecrosis of the Jaw in Cancer Patients: Result from the OneFlorida Clinical Research Consortium. J Bone Miner Res. 2022 12; 37(12):2466-2471.
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Eisen A, Somerfield MR, Accordino MK, Blanchette PS, Clemons MJ, Dhesy-Thind S, Dillmon MS, D'Oronzo S, Fletcher GG, Frank ES, Hallmeyer S, Makhoul I, Moy B, Thawer A, Wu JY, Van Poznak CH. Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update. J Clin Oncol. 2022 03 01; 40(7):787-800.
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Suva LJ, Cooper A, Watts AE, Ebetino FH, Price J, Gaddy D. Bisphosphonates in veterinary medicine: The new horizon for use. Bone. 2021 01; 142:115711.
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Surface LE, Burrow DT, Li J, Park J, Kumar S, Lyu C, Song N, Yu Z, Rajagopal A, Bae Y, Lee BH, Mumm S, Gu CC, Baker JC, Mohseni M, Sum M, Huskey M, Duan S, Bijanki VN, Civitelli R, Gardner MJ, McAndrew CM, Ricci WM, Gurnett CA, Diemer K, Wan F, Costantino CL, Shannon KM, Raje N, Dodson TB, Haber DA, Carette JE, Varadarajan M, Brummelkamp TR, Birsoy K, Sabatini DM, Haller G, Peterson TR. ATRAID regulates the action of nitrogen-containing bisphosphonates on bone. Sci Transl Med. 2020 05 20; 12(544).
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Gurram PR, Castillo NE, Esquer Garrigos Z, Vijayvargiya P, Abu Saleh OM. A Dimorphic Diagnosis of a Pleomorphic Disease: An Unusual Cause of Hypercalcemia. Am J Med. 2020 11; 133(11):e659-e662.
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Mitchell A, Watts AE, Ebetino FH, Suva LJ. Bisphosphonate use in the horse: what is good and what is not? BMC Vet Res. 2019 Jun 24; 15(1):211.
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Lionikaite V, Gustafsson KL, Westerlund A, Windahl SH, Koskela A, Tuukkanen J, Johansson H, Ohlsson C, Conaway HH, Henning P, Lerner UH. Clinically relevant doses of vitamin A decrease cortical bone mass in mice J Endocrinol. 2018 10 31; 239(3):389-402.
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Jain N, Reilly RF. Hungry bone syndrome. Curr Opin Nephrol Hypertens. 2017 07; 26(4):250-255.
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Lipton A, Smith MR, Fizazi K, Stopeck AT, Henry D, Brown JE, Shore ND, Saad F, Spencer A, Zhu L, Warner DJ. Changes in Bone Turnover Marker Levels and Clinical Outcomes in Patients with Advanced Cancer and Bone Metastases Treated with Bone Antiresorptive Agents. Clin Cancer Res. 2016 Dec 01; 22(23):5713-5721.
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Tripathi R, Singh P, Singh A, Chagtoo M, Khan S, Tiwari S, Agarwal G, Meeran SM, Godbole MM. Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress. Nutr Cancer. 2016 May-Jun; 68(4):679-88.
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Kennel KA, Maraka S. Authors' reply to Minisola and colleagues, Kausar, and Sharvill. BMJ. 2015 Nov 04; 351:h5873.
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