Core Binding Factor Alpha 1 Subunit
"Core Binding Factor Alpha 1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
Descriptor ID |
D050659
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MeSH Number(s) |
D12.776.930.155.200.100
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Concept/Terms |
Core Binding Factor Alpha 1 Subunit- Core Binding Factor Alpha 1 Subunit
- AML3 Transcription Factor
- CBFA-1 Protein
- CBFA 1 Protein
- CBFA1 Protein
- SL3-3 Enhancer Factor 1
- SL3 3 Enhancer Factor 1
- CBFalpha1 Protein
- Osf2 Transcription Factor
- PEBP2alphaA Protein
- Runx2 Protein
- SEF1 Protein
- Acute Myeloid Leukemia 3 Protein
- CBFalpha Runt Domain Transcription Factor 1
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Below are MeSH descriptors whose meaning is more general than "Core Binding Factor Alpha 1 Subunit".
Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor Alpha 1 Subunit".
This graph shows the total number of publications written about "Core Binding Factor Alpha 1 Subunit" by people in UAMS Profiles by year, and whether "Core Binding Factor Alpha 1 Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2018 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2015 | 1 | 2 | 3 | 2012 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2010 | 0 | 2 | 2 | 2009 | 0 | 1 | 1 | 2008 | 0 | 2 | 2 | 2007 | 1 | 1 | 2 | 2006 | 0 | 2 | 2 | 2005 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2003 | 0 | 2 | 2 | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Core Binding Factor Alpha 1 Subunit" by people in Profiles over the past ten years.
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Xiong J, Almeida M, O'Brien CA. The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation. Bone. 2018 07; 112:1-9.
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Smith SS, Dole NS, Franceschetti T, Hrdlicka HC, Delany AM. MicroRNA-433 Dampens Glucocorticoid Receptor Signaling, Impacting Circadian Rhythm and Osteoblastic Gene Expression. J Biol Chem. 2016 Oct 07; 291(41):21717-21728.
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Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016 Mar; 15(3):765-75.
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Meyer MB, Benkusky NA, Onal M, Pike JW. Selective regulation of Mmp13 by 1,25(OH)2D3, PTH, and Osterix through distal enhancers. J Steroid Biochem Mol Biol. 2016 11; 164:258-264.
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Trotter TN, Li M, Pan Q, Peker D, Rowan PD, Li J, Zhan F, Suva LJ, Javed A, Yang Y. Myeloma cell-derived Runx2 promotes myeloma progression in bone. Blood. 2015 Jun 04; 125(23):3598-608.
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