Core Binding Factor Alpha 1 Subunit
"Core Binding Factor Alpha 1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
| Descriptor ID |
D050659
|
| MeSH Number(s) |
D12.776.930.155.200.100
|
| Concept/Terms |
Core Binding Factor Alpha 1 Subunit- Core Binding Factor Alpha 1 Subunit
- AML3 Transcription Factor
- CBFA-1 Protein
- CBFA 1 Protein
- CBFA1 Protein
- SL3-3 Enhancer Factor 1
- SL3 3 Enhancer Factor 1
- CBFalpha1 Protein
- Osf2 Transcription Factor
- PEBP2alphaA Protein
- Runx2 Protein
- SEF1 Protein
- Acute Myeloid Leukemia 3 Protein
- CBFalpha Runt Domain Transcription Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Core Binding Factor Alpha 1 Subunit".
Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor Alpha 1 Subunit".
This graph shows the total number of publications written about "Core Binding Factor Alpha 1 Subunit" by people in UAMS Profiles by year, and whether "Core Binding Factor Alpha 1 Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2015 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2007 | 1 | 1 | 2 |
| 2006 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Core Binding Factor Alpha 1 Subunit" by people in Profiles over the past ten years.
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Heredero-Jim?nez S, Mart?n-Guerrero E, Pizarro-G?mez J, Tirado-Cabrera I, ?lvarez-Carri?n L, Bellido T, Gort?zar AR, Ardura JA. Caveolin-1 Regulates Parathyroid Hormone (PTH)-Related Protein (PTHrP) Actions on PTH Receptor Type 1 in Bone Cells. J Cell Physiol. 2025 Jul; 240(7):e70067.
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Xiong J, Almeida M, O'Brien CA. The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation. Bone. 2018 07; 112:1-9.
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Smith SS, Dole NS, Franceschetti T, Hrdlicka HC, Delany AM. MicroRNA-433 Dampens Glucocorticoid Receptor Signaling, Impacting Circadian Rhythm and Osteoblastic Gene Expression. J Biol Chem. 2016 Oct 07; 291(41):21717-21728.