 CDC2 Protein Kinase
"CDC2 Protein Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
| Descriptor ID |
D016203
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| MeSH Number(s) |
D08.811.913.696.620.682.700.200.067.249 D08.811.913.696.620.682.700.200.580.500 D12.644.360.250.067.249 D12.644.360.250.580.500 D12.776.167.200.067.249 D12.776.167.200.580.500 D12.776.476.250.067.249 D12.776.476.250.580.500 D12.776.744.360
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| Concept/Terms |
CDC2 Protein Kinase- CDC2 Protein Kinase
- Protein Kinase, CDC2
- Cyclin-Dependent Kinase 1
- Cyclin Dependent Kinase 1
- Cdk1 Protein Kinase
- Protein Kinase, Cdk1
- cdc2+ Protein
- cdk1 Kinase
p34cdc2 Protein- p34cdc2 Protein
- Protein p34cdc2
- p34cdc2, Protein
- Histone Kinase p34(cdc2)
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Below are MeSH descriptors whose meaning is more general than "CDC2 Protein Kinase".
Below are MeSH descriptors whose meaning is more specific than "CDC2 Protein Kinase".
This graph shows the total number of publications written about "CDC2 Protein Kinase" by people in UAMS Profiles by year, and whether "CDC2 Protein Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 |
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Below are the most recent publications written about "CDC2 Protein Kinase" by people in Profiles over the past ten years.
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Van Matre S, Huq S, Akana L, Eldridge DE, Zuniga O, Rodrigues H, Wolfe AR. Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1. Radiother Oncol. 2024 Nov; 200:110531.
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Chu R, Alford SE, Hart K, Kothari A, Mackintosh SG, Kovak MR, Chambers TC. Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified. Oncotarget. 2016 Nov 29; 7(48):78958-78970.
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Kothari A, Chambers TC. CDK1/2 toolbox in need of an upgrade. Cell Cycle. 2016 07 02; 15(13):1663-4.
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