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Brendan Frett

Concepts (156)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
20
2024
205
5.040
Why?
Proto-Oncogene Proteins c-ret
11
2024
33
4.360
Why?
Drug Discovery
11
2024
83
3.230
Why?
Antineoplastic Agents
16
2024
1178
1.930
Why?
Pyridines
6
2021
132
1.200
Why?
Neoplasms
7
2021
1237
1.130
Why?
Drug Design
9
2021
119
1.040
Why?
Small Molecule Libraries
6
2021
67
1.030
Why?
Leukemia, Myeloid, Acute
2
2024
180
0.960
Why?
Transforming Growth Factor beta
2
2022
136
0.920
Why?
Molecular Structure
11
2024
293
0.860
Why?
Gene Rearrangement
1
2024
74
0.860
Why?
fms-Like Tyrosine Kinase 3
3
2021
16
0.830
Why?
Lung Neoplasms
3
2024
600
0.820
Why?
Cell Line, Tumor
17
2024
1399
0.820
Why?
Structure-Activity Relationship
12
2024
394
0.810
Why?
Aminoquinolines
1
2021
7
0.770
Why?
Receptor, trkA
4
2024
7
0.760
Why?
Adenine
1
2021
31
0.740
Why?
Pyrazoles
2
2021
111
0.730
Why?
Intracellular Signaling Peptides and Proteins
1
2021
139
0.720
Why?
Imidazoles
2
2018
128
0.700
Why?
Tumor Microenvironment
1
2022
223
0.690
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
30
0.670
Why?
Pyrimidines
5
2024
193
0.560
Why?
ras Proteins
2
2013
65
0.530
Why?
Computer-Aided Design
1
2015
21
0.480
Why?
Dose-Response Relationship, Drug
6
2021
1356
0.480
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.440
Why?
Proto-Oncogene Proteins
2
2013
156
0.440
Why?
Humans
32
2024
50389
0.440
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
104
0.390
Why?
HEK293 Cells
4
2021
216
0.390
Why?
Cell Proliferation
8
2022
989
0.360
Why?
Models, Molecular
4
2020
334
0.360
Why?
Receptor, trkB
2
2021
6
0.340
Why?
Molecular Conformation
3
2019
66
0.310
Why?
Animals
12
2024
13173
0.310
Why?
Signal Transduction
5
2022
1625
0.270
Why?
Molecular Docking Simulation
3
2021
72
0.250
Why?
Chromones
1
2024
17
0.230
Why?
DNA-Activated Protein Kinase
1
2024
22
0.230
Why?
Solubility
1
2024
72
0.230
Why?
Morpholines
1
2024
66
0.230
Why?
Phosphorylation
4
2021
527
0.230
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.230
Why?
Proto-Oncogenes
1
2024
27
0.230
Why?
Mice
7
2024
5688
0.220
Why?
NIH 3T3 Cells
3
2021
51
0.220
Why?
Lymphoma
1
2024
65
0.210
Why?
Patents as Topic
1
2022
9
0.210
Why?
Drug Evaluation, Preclinical
3
2021
145
0.210
Why?
Mutation
4
2022
1292
0.210
Why?
CARD Signaling Adaptor Proteins
1
2022
5
0.200
Why?
Drug Screening Assays, Antitumor
5
2021
131
0.200
Why?
Chemistry Techniques, Synthetic
3
2020
20
0.200
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
152
0.200
Why?
Clinical Trials as Topic
2
2021
465
0.190
Why?
Transfection
1
2022
354
0.190
Why?
Indoles
1
2024
273
0.190
Why?
Phthalazines
1
2021
20
0.190
Why?
Thiophenes
1
2021
36
0.190
Why?
Acetamides
1
2021
18
0.180
Why?
Quinazolines
1
2020
32
0.180
Why?
Cell Line
3
2021
1010
0.170
Why?
Aziridines
1
2020
2
0.170
Why?
Maleimides
1
2020
8
0.170
Why?
Pyrroles
1
2020
68
0.170
Why?
Protein Interaction Mapping
1
2020
37
0.170
Why?
Ketones
1
2019
9
0.170
Why?
Molecular Dynamics Simulation
1
2019
34
0.170
Why?
Phosphoproteins
1
2020
117
0.160
Why?
Oxidative Stress
1
2024
763
0.160
Why?
Adenosine Triphosphate
1
2020
230
0.160
Why?
Oligopeptides
1
2019
95
0.160
Why?
Decarboxylation
1
2018
3
0.160
Why?
Apoptosis
3
2022
1094
0.160
Why?
Receptor, trkC
1
2018
4
0.160
Why?
Metabolome
1
2019
92
0.160
Why?
Models, Chemical
1
2018
64
0.160
Why?
Isoquinolines
1
2018
28
0.150
Why?
Mice, Nude
2
2017
252
0.150
Why?
Bone Marrow
1
2020
356
0.150
Why?
Computational Biology
1
2020
215
0.150
Why?
Benzimidazoles
1
2018
49
0.150
Why?
Proto-Oncogene Proteins c-kit
1
2018
36
0.150
Why?
Software
1
2020
274
0.150
Why?
Heterocyclic Compounds
1
2018
29
0.150
Why?
Boronic Acids
1
2018
182
0.150
Why?
Ligands
2
2015
203
0.140
Why?
Proteomics
1
2020
299
0.140
Why?
Nitrazepam
1
2016
1
0.140
Why?
Glioblastoma
1
2017
92
0.130
Why?
Libraries, Digital
1
2015
2
0.120
Why?
Molecular Weight
1
2015
85
0.120
Why?
Carboxylic Acids
1
2015
17
0.120
Why?
Colorectal Neoplasms
1
2018
256
0.120
Why?
Human Umbilical Vein Endothelial Cells
1
2015
90
0.120
Why?
Palladium
1
2014
4
0.120
Why?
Brain Neoplasms
1
2017
288
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
20
0.110
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
66
0.110
Why?
Molecular Targeted Therapy
1
2013
121
0.100
Why?
Drug Resistance, Neoplasm
1
2013
318
0.090
Why?
Cells, Cultured
1
2014
1589
0.090
Why?
Cell Survival
2
2021
590
0.080
Why?
Mice, Inbred BALB C
2
2020
297
0.080
Why?
Protein Binding
2
2020
657
0.080
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
DNA Damage
1
2024
300
0.050
Why?
Furans
1
2022
26
0.050
Why?
Oncogenes
1
2022
57
0.050
Why?
T-Lymphocytes
1
2024
331
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
85
0.050
Why?
Receptors, Transforming Growth Factor beta
1
2021
25
0.050
Why?
Smad Proteins
1
2021
11
0.050
Why?
Tumor Cells, Cultured
1
2022
462
0.050
Why?
Blood-Brain Barrier
1
2021
48
0.050
Why?
Wound Healing
1
2022
203
0.040
Why?
Binding, Competitive
1
2020
94
0.040
Why?
Amino Acid Motifs
1
2020
57
0.040
Why?
Hematopoiesis
1
2020
71
0.040
Why?
Workflow
1
2020
51
0.040
Why?
Binding Sites
1
2021
378
0.040
Why?
Xenopus laevis
1
2019
42
0.040
Why?
Protein Structure, Secondary
1
2019
71
0.040
Why?
Databases, Genetic
1
2020
88
0.040
Why?
Ethanol
1
2022
336
0.040
Why?
Stereoisomerism
1
2019
101
0.040
Why?
Cell Movement
1
2020
246
0.040
Why?
Mass Spectrometry
1
2020
284
0.040
Why?
Catalytic Domain
1
2018
57
0.040
Why?
Cell Cycle Checkpoints
1
2018
30
0.040
Why?
Female
4
2020
26981
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Neoplasm Transplantation
1
2017
84
0.040
Why?
Enzyme Activation
1
2018
272
0.040
Why?
Gene Silencing
1
2017
114
0.030
Why?
M Phase Cell Cycle Checkpoints
1
2016
4
0.030
Why?
Polyploidy
1
2016
11
0.030
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
8
0.030
Why?
Neoplastic Stem Cells
1
2017
100
0.030
Why?
Protein Conformation
1
2016
165
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
213
0.030
Why?
Hydrazines
1
2015
17
0.030
Why?
Solvents
1
2015
29
0.030
Why?
Metals
1
2015
35
0.030
Why?
Carbon
1
2015
55
0.030
Why?
Rats, Sprague-Dawley
1
2018
1582
0.030
Why?
Microwaves
1
2014
11
0.030
Why?
Catalysis
1
2014
89
0.030
Why?
Kinetics
1
2015
635
0.030
Why?
Cell Cycle Proteins
1
2013
168
0.020
Why?
Rats
1
2016
3287
0.020
Why?
Models, Biological
1
2013
723
0.020
Why?
Male
2
2020
25718
0.020
Why?
Frett's Networks
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