Cell Cycle Checkpoints
"Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Descriptor ID |
D059447
|
MeSH Number(s) |
G04.299.134.109
|
Concept/Terms |
Cell Cycle Checkpoints- Cell Cycle Checkpoints
- Cell Cycle Checkpoint
- Checkpoint, Cell Cycle
- Checkpoints, Cell Cycle
Cell Cycle Control- Cell Cycle Control
- Cell Cycle Controls
- Control, Cell Cycle
- Controls, Cell Cycle
Cell Cycle Transition Points- Cell Cycle Transition Points
- Cell Cycle-Transition Points
- Cell Cycle-Transition Point
- Cycle-Transition Point, Cell
- Point, Cell Cycle-Transition
Cell Cycle Arrest- Cell Cycle Arrest
- Arrest, Cell Cycle
- Arrests, Cell Cycle
- Cell Cycle Arrests
|
Below are MeSH descriptors whose meaning is more general than "Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "Cell Cycle Checkpoints".
This graph shows the total number of publications written about "Cell Cycle Checkpoints" by people in UAMS Profiles by year, and whether "Cell Cycle Checkpoints" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
2019 | 2 | 1 | 3 | 2017 | 1 | 4 | 5 | 2015 | 0 | 2 | 2 | 2014 | 1 | 0 | 1 | 2013 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Cell Cycle Checkpoints" by people in Profiles over the past ten years.
-
Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, Narita M, Niedernhofer L, Passos JF, Robbins PD, Schmitt CA, Sedivy J, Vougas K, von Zglinicki T, Zhou D, Serrano M, Demaria M. Cellular Senescence: Defining a Path Forward. Cell. 2019 10 31; 179(4):813-827.
-
Shields BD, Koss B, Taylor EM, Storey AJ, West KL, Byrum SD, Mackintosh SG, Edmondson R, Mahmoud F, Shalin SC, Tackett AJ. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer Res. 2019 03 15; 79(6):1113-1123.
-
Choi K, Abu-Sbeih H, Samdani R, Nogueras Gonzalez G, Raju GS, Richards DM, Gao J, Subudhi S, Stroehlein J, Wang Y. Can Immune Checkpoint Inhibitors Induce Microscopic Colitis or a Brand New Entity? Inflamm Bowel Dis. 2019 01 10; 25(2):385-393.
-
Naumov A, Kratzer S, Ting LM, Kim K, Suvorova ES, White MW. The Toxoplasma Centrocone Houses Cell Cycle Regulatory Factors. mBio. 2017 08 22; 8(4).
-
Petibone DM, Mustafa T, Bourdo SE, Lafont A, Ding W, Karmakar A, Nima ZA, Watanabe F, Casciano D, Morris SM, Dobrovolsky VN, Biris AS. p53-competent cells and p53-deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity. J Appl Toxicol. 2017 Nov; 37(11):1333-1345.
-
Tao Y, Yang G, Yang H, Song D, Hu L, Xie B, Wang H, Gao L, Gao M, Xu H, Xu Z, Wu X, Zhang Y, Zhu W, Zhan F, Shi J. TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma. Oncotarget. 2017 Apr 18; 8(16):26718-26731.
-
Pawlyn C, Bright MD, Buros AF, Stein CK, Walters Z, Aronson LI, Mirabella F, Jones JR, Kaiser MF, Walker BA, Jackson GH, Clarke PA, Bergsagel PL, Workman P, Chesi M, Morgan GJ, Davies FE. Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control. Blood Cancer J. 2017 03 31; 7(3):e549.
-
Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, M?ller S, Oppermann U, Brennan PE. Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol. 2017 Mar 16; 24(3):371-380.
-
Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z. Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma. Blood. 2015 Dec 24; 126(26):2821-31.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|