 Isoquinolines
"Isoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
| Descriptor ID |
D007546
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| MeSH Number(s) |
D03.438.531
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isoquinolines".
Below are MeSH descriptors whose meaning is more specific than "Isoquinolines".
This graph shows the total number of publications written about "Isoquinolines" by people in UAMS Profiles by year, and whether "Isoquinolines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2007 | 0 | 3 | 3 | | 2006 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1995 | 1 | 1 | 2 | | 1994 | 2 | 0 | 2 | | 1993 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoquinolines" by people in Profiles over the past ten years.
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Zhang X, Thummuri D, He Y, Liu X, Zhang P, Zhou D, Zheng G. Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-XL. Chem Commun (Camb). 2019 Dec 05; 55(98):14765-14768.
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Melchior B, Mittapalli GK, Lai C, Duong-Polk K, Stewart J, G?ner B, Hofilena B, Tjitro A, Anderson SD, Herman DS, Dellamary L, Swearingen CJ, Sunil KC, Yazici Y. Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: A potential therapeutic for Alzheimer's disease. Aging Cell. 2019 10; 18(5):e13000.
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He LJ, Yang DL, Li SQ, Zhang YJ, Tang Y, Lei J, Frett B, Lin HK, Li HY, Chen ZZ, Xu ZG. Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells. Bioorg Med Chem. 2018 08 07; 26(14):3899-3908.
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