 Binding, Competitive
"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
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| MeSH Number(s) |
E05.196.080 G02.111.087.090 G02.111.570.120.309 G02.149.115.090
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in UAMS Profiles by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2011 | 0 | 2 | 2 | | 2008 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2005 | 0 | 5 | 5 | | 2004 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 1998 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1996 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1993 | 0 | 4 | 4 | | 1990 | 0 | 5 | 5 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles over the past ten years.
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Lakkaniga NR, Zhang L, Belachew B, Gunaganti N, Frett B, Li HY. Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression. Eur J Med Chem. 2020 Oct 01; 203:112589.
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Franks LN, Ford BM, Fujiwara T, Zhao H, Prather PL. The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects. Toxicol Appl Pharmacol. 2018 08 15; 353:31-42.
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Walton BM, Jackson GW, Deutz N, Cote G. Surface-enhanced Raman spectroscopy competitive binding biosensor development utilizing surface modification of silver nanocubes and a citrulline aptamer. J Biomed Opt. 2017 07 01; 22(7):75002.
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Nazim M, Masuda A, Rahman MA, Nasrin F, Takeda JI, Ohe K, Ohkawara B, Ito M, Ohno K. Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms. Nucleic Acids Res. 2017 02 17; 45(3):1455-1468.
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Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016; 11(12):e0167240.
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