 Fibrosis
"Fibrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Descriptor ID |
D005355
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| MeSH Number(s) |
C23.550.355
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fibrosis".
Below are MeSH descriptors whose meaning is more specific than "Fibrosis".
This graph shows the total number of publications written about "Fibrosis" by people in UAMS Profiles by year, and whether "Fibrosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 3 | 4 | | 2023 | 0 | 4 | 4 | | 2022 | 0 | 6 | 6 | | 2021 | 0 | 4 | 4 | | 2020 | 1 | 5 | 6 | | 2019 | 0 | 9 | 9 | | 2018 | 0 | 2 | 2 | | 2017 | 0 | 9 | 9 | | 2016 | 0 | 3 | 3 | | 2015 | 0 | 3 | 3 | | 2014 | 0 | 10 | 10 | | 2013 | 0 | 5 | 5 | | 2012 | 0 | 3 | 3 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 3 | 3 | | 2009 | 0 | 2 | 2 | | 2008 | 0 | 4 | 4 | | 2007 | 2 | 6 | 8 | | 2006 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibrosis" by people in Profiles over the past ten years.
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Hao J, Qiang P, Fan L, Xiong Y, Chang Y, Yang F, Wang X, Shimosawa T, Mu S, Xu Q. Eplerenone reduces lymphangiogenesis in the contralateral kidneys of UUO rats. Sci Rep. 2024 05 01; 14(1):9976.
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Duarte-Rojo A, Patel K, Rockey DC. Noninvasive assessment of liver fibrosis and portal hypertension. Curr Opin Gastroenterol. 2024 05 01; 40(3):148-155.
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Goorani S, Khan AH, Mishra A, El-Meanawy A, Imig JD. Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences. Kidney Blood Press Res. 2024; 49(1):69-80.
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Khan MAH, Nolan B, Stavniichuk A, Merk D, Imig JD. Dual soluble epoxide hydrolase inhibitor - farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis. Front Immunol. 2023; 14:1269261.
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Tanaka S, Portilla D, Okusa MD. Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis. Nat Rev Nephrol. 2023 11; 19(11):721-732.
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Li S, Livingston MJ, Ma Z, Hu X, Wen L, Ding HF, Zhou D, Dong Z. Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity. JCI Insight. 2023 04 24; 8(8).
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Maeso-D?az R, Du K, Pan C, Guy CD, Oh SH, Chen T, Wang L, Ko DC, Tang L, Dutta RK, Jun JH, Suzuki A, Abdelmalek MF, Wang XF, Diehl AM. Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression. Hepatology. 2023 10 01; 78(4):1209-1222.
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Hameed I, Hayat J, Marsia S, Samad SA, Khan R, Siddiqui OM, Khan MO, Malik S, Fatima K, Fudim M, Krasuski RA. Comparison of sodium-glucose cotransporter-2 inhibitors and thiazolidinediones for management of non-alcoholic fatty liver disease: A systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2023 05; 47(5):102111.
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Imig JD, Khan MAH, Stavniichuk A, Jankiewicz WK, Goorani S, Yeboah MM, El-Meanawy A. Salt-sensitive hypertension after reversal of unilateral ureteral obstruction. Biochem Pharmacol. 2023 04; 210:115438.
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Nagalingam RS, Chattopadhyaya S, Al-Hattab DS, Cheung DYC, Schwartz LY, Jana S, Aroutiounova N, Ledingham DA, Moffatt TL, Landry NM, Bagchi RA, Dixon IMC, Wigle JT, Oudit GY, Kassiri Z, Jassal DS, Czubryt MP. Scleraxis and fibrosis in the pressure-overloaded heart. Eur Heart J. 2022 12 01; 43(45):4739-4750.
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Goh X, Muzaffar J, Bance M. Cochlear implantation in systemic autoimmune disease. Curr Opin Otolaryngol Head Neck Surg. 2022 Oct 01; 30(5):291-297.
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Sahu RK, Xavier S, Chauss D, Wang L, Chew C, Taylor R, Stallcup WB, Ma JZ, Kazemian M, Afzali B, K?hl J, Portilla D. Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells. Am J Physiol Renal Physiol. 2022 06 01; 322(6):F597-F610.
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Lin FP, Bloomer PM, Grubbs RK, Rockette-Wagner B, Tevar AD, Dunn MA, Duarte-Rojo A. Low Daily Step Count Is Associated With a High Risk of Hospital Admission and Death in Community-Dwelling Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2022 08; 20(8):1813-1820.e2.
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Drummer DJ, McAdam JS, Seay R, Aban I, Lavin KM, Wiggins D, Touliatos G, Yang S, Kelley C, Tuggle SC, Peoples B, Siegel H, Ghanem E, Singh JA, Schutzler S, Barnes CL, Ferrando AA, Bridges SL, Bamman MM. Perioperative assessment of muscle inflammation susceptibility in patients with end-stage osteoarthritis. J Appl Physiol (1985). 2022 04 01; 132(4):984-994.
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Chiang KC, Imig JD, Kalantar-Zadeh K, Gupta A. Kidney in the net of acute and long-haul coronavirus disease 2019: a potential role for lipid mediators in causing renal injury and fibrosis. Curr Opin Nephrol Hypertens. 2022 01 01; 31(1):36-46.
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Saiman Y, Duarte-Rojo A, Rinella ME. Fatty Liver Disease: Diagnosis and Stratification. Annu Rev Med. 2022 01 27; 73:529-544.
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Henson SE, Lang SM, Khoury PR, Tian C, Rutter MM, Urbina EM, Ryan TD, Taylor MD, Alsaied T. The Effect of Adiposity on Cardiovascular Function and Myocardial Fibrosis in Patients With Duchenne Muscular Dystrophy. J Am Heart Assoc. 2021 10 05; 10(19):e021037.
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Kore RA, Wang X, Henson JC, Ding Z, Jamshidi-Parsian A, Mehta JL. Proteomic basis of modulation of postischemic fibrosis by MSC exosomes. Am J Physiol Regul Integr Comp Physiol. 2021 11 01; 321(5):R639-R654.
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Nishimura Y, Fajgenbaum DC, Pierson SK, Iwaki N, Nishikori A, Kawano M, Nakamura N, Izutsu K, Takeuchi K, Nishimura MF, Maeda Y, Otsuka F, Yoshizaki K, Oksenhendler E, van Rhee F, Sato Y. Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease. Am J Hematol. 2021 10 01; 96(10):1241-1252.
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Deng P, Wang C, Wahlang B, Sexton T, Morris AJ, Hennig B. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice. Toxicol Appl Pharmacol. 2020 12 15; 409:115301.
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Alsaied T, Moore RA, Lang SM, Truong V, Lubert AM, Veldtman GR, Averin K, Dillman JR, Trout AT, Mazur W, Taylor MD, He Q, Morales DL, Redington AN, Goldstein BH. Myocardial fibrosis, diastolic dysfunction and elevated liver stiffness in the Fontan circulation. Open Heart. 2020 10; 7(2).
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Plotkin M, O'Brien CA, Goellner J, Williams J, Carter W, Sharma S, Stone A. A Uromodulin Mutation Drives Autoimmunity and Kidney Mononuclear Phagocyte Endoplasmic Reticulum Stress. Am J Pathol. 2020 12; 190(12):2436-2452.
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Sears SM, Sharp CN, Krueger A, Oropilla GB, Saforo D, Doll MA, Megyesi J, Beverly LJ, Siskind LJ. C57BL/6 mice require a higher dose of cisplatin to induce renal fibrosis and CCL2 correlates with cisplatin-induced kidney injury. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F674-F685.
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Lepe M, Oltulu P, Canepa M, Wu RI, Deeken A, Alex D, Dinares C, Doxtader EE, Fitzhugh VA, Gibier JB, Jain D, Janaki N, Jelinek A, Labiano T, L'Imperio V, Michael C, Mukhopadhyay S, Pagni F, Panizo A, Pijuan L, Quintana LM, Roy-Chowdhuri S, Sanchez-Font A, Sansano I, Sauter J, Skipper D, Spruill LS, Torous V, Gardner JM, Jiang XS. #EBUSTwitter: Novel Use of Social Media for Conception, Coordination, and Completion of an International, Multicenter Pathology Study. Arch Pathol Lab Med. 2020 07 01; 144(7):878-882.
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Stavniichuk A, Hye Khan MA, Yeboah MM, Chesnik MA, Jankiewicz WK, Hartmann M, Bl?cher R, Kircher T, Savchuk O, Proschak E, Imig JD. Dual soluble epoxide hydrolase inhibitor/PPAR-? agonist attenuates renal fibrosis. Prostaglandins Other Lipid Mediat. 2020 10; 150:106472.
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Nhu QM, Hsieh L, Dohil L, Dohil R, Newbury RO, Kurten R, Moawad FJ, Aceves SS. Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation. Clin Transl Gastroenterol. 2020 04; 11(4):e00164.
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Gerstle K, Tanager K, Hegde S, Chung JH, Husain AN, Applebaum MA, Dyamenahalli U. Pleuroparenchymal fibroelastosis in an 8-year old treated for neuroblastoma. Pediatr Pulmonol. 2020 03; 55(3):E1-E4.
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Kaushal GP, Chandrashekar K, Juncos LA, Shah SV. Autophagy Function and Regulation in Kidney Disease. Biomolecules. 2020 01 07; 10(1).
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Fu Q, Lu Z, Fu X, Ma S, Lu X. MicroRNA 27b promotes cardiac fibrosis by targeting the FBW7/Snail pathway. Aging (Albany NY). 2019 12 23; 11(24):11865-11879.
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Sarkar M, Yates K, Suzuki A, Lavine J, Gill R, Ziegler T, Terrault N, Dhindsa S. Low Testosterone Is Associated With Nonalcoholic Steatohepatitis and Fibrosis Severity in Men. Clin Gastroenterol Hepatol. 2021 02; 19(2):400-402.e2.
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Heo SY, Jeong MS, Lee HS, Kim YJ, Park SH, Jung WK. Phlorofucofuroeckol A from Ecklonia cava ameliorates TGF-?1-induced fibrotic response of human tracheal fibroblasts via the downregulation of MAPKs and SMAD 2/3 pathways inactivated TGF-? receptor. Biochem Biophys Res Commun. 2020 Feb 12; 522(3):626-632.
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Atluri K, Brouillette MJ, Seol D, Khorsand B, Sander E, Salem AK, Fredericks D, Petersen E, Smith S, Fowler TP, Martin JA. Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. J Orthop Res. 2020 03; 38(3):629-638.
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Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. Circ Res. 2019 09 13; 125(7):662-677.
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Widiapradja A, Manteufel EJ, Dehlin HM, Pena J, Goldspink PH, Sharma A, Kolb LL, Imig JD, Janicki JS, Lu B, Levick SP. Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart. Sci Rep. 2019 07 29; 9(1):11004.
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Wei T, Shalin S, Draper E, Miller E, Zhang H, Sun R, Lee M, Albert G, Richter GT. Abnormal elastin and collagen deposition is present in extracranial arteriovenous malformations: A comparison to intracranial disease. Histol Histopathol. 2019 Dec; 34(12):1355-1363.
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Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R. Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease. Kidney Int. 2019 04; 95(4):797-814.
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Dworatzek E, Mahmoodzadeh S, Schriever C, Kusumoto K, Kramer L, Santos G, Fliegner D, Leung YK, Ho SM, Zimmermann WH, Lutz S, Regitz-Zagrosek V. Sex-specific regulation of collagen I and III expression by 17?-Estradiol in cardiac fibroblasts: role of estrogen receptors. Cardiovasc Res. 2019 02 01; 115(2):315-327.
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Hintermann E, Bayer M, Conti CB, Fuchs S, Fausther M, Leung PS, Aurrand-Lions M, Taubert R, Pfeilschifter JM, Friedrich-Rust M, Schuppan D, Dranoff JA, Gershwin ME, Manns MP, Imhof BA, Christen U. Junctional adhesion molecules JAM-B and JAM-C promote autoimmune-mediated liver fibrosis in mice. J Autoimmun. 2018 07; 91:83-96.
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Lopategui DM, Balise RR, Bouzoubaa LA, Wilson SK, Kava BR. The Impact of Immediate Salvage Surgery on Corporeal Length Preservation in Patients Presenting with Penile Implant Infections. J Urol. 2018 07; 200(1):171-177.
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Sharp CN, Doll MA, Megyesi J, Oropilla GB, Beverly LJ, Siskind LJ. Subclinical kidney injury induced by repeated cisplatin administration results in progressive chronic kidney disease. Am J Physiol Renal Physiol. 2018 07 01; 315(1):F161-F172.
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Nickeleit V, Singh HK, Randhawa P, Drachenberg CB, Bhatnagar R, Bracamonte E, Chang A, Chon WJ, Dadhania D, Davis VG, Hopfer H, Mihatsch MJ, Papadimitriou JC, Schaub S, Stokes MB, Tungekar MF, Seshan SV. The Banff Working Group Classification of Definitive Polyomavirus Nephropathy: Morphologic Definitions and Clinical Correlations. J Am Soc Nephrol. 2018 02; 29(2):680-693.
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Leung CS, Yeung TL, Yip KP, Wong KK, Ho SY, Mangala LS, Sood AK, Lopez-Berestein G, Sheng J, Wong ST, Birrer MJ, Mok SC. Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance. J Clin Invest. 2018 02 01; 128(2):589-606.
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Garcia-Saenz-de-Sicilia M, Duarte-Rojo A. Hepatic Steatosis and its Effects on Fibrosis in Patients With Chronic Hepatitis B Virus Infection. Clin Gastroenterol Hepatol. 2018 04; 16(4):491-494.
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Ayoub KF, Pothineni NVK, Rutland J, Ding Z, Mehta JL. Immunity, Inflammation, and Oxidative Stress in Heart Failure: Emerging Molecular Targets. Cardiovasc Drugs Ther. 2017 Dec; 31(5-6):593-608.
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Bhatta A, Yao L, Xu Z, Toque HA, Chen J, Atawia RT, Fouda AY, Bagi Z, Lucas R, Caldwell RB, Caldwell RW. Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1. Cardiovasc Res. 2017 Nov 01; 113(13):1664-1676.
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Uberoi AS, Badgwell BD, Bhutani MS. An Unusual Gastric Antral Mass. Gastroenterology. 2018 Apr; 154(5):e16-e17.
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Wang J, Pathak R, Garg S, Hauer-Jensen M. Fibrinogen deficiency suppresses the development of early and delayed radiation enteropathy. World J Gastroenterol. 2017 Jul 14; 23(26):4701-4711.
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Pandey S, Rosenbaum E, Cottler-Fox M, Harville TO. Percent cPRA (Calculated Panel Reactive Antibody) Value Predicts Percent of Positive Platelet Crossmatches. Ann Clin Lab Sci. 2017 May; 47(3):315-318.
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Bagchi AK, Akolkar G, Mandal S, Ayyappan P, Yang X, Singal PK. Toll-like receptor 2 dominance over Toll-like receptor 4 in stressful conditions for its detrimental role in the heart. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1238-H1247.
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Schmitt VH, Mamilos A, Schmitt C, Neitzer-Planck CNE, Rajab TK, Hollemann D, Wagner W, Kr?mer B, Hierlemann H, James Kirkpatrick C, Brochhausen C. Tissue response to five commercially available peritoneal adhesion barriers-A systematic histological evaluation. J Biomed Mater Res B Appl Biomater. 2018 02; 106(2):598-609.
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Brochhausen C, Schmitt VH, Mamilos A, Schmitt C, Planck CN, Rajab TK, Hierlemann H, Kirkpatrick CJ. Expression of CD68 positive macrophages in the use of different barrier materials to prevent peritoneal adhesions-an animal study. J Mater Sci Mater Med. 2017 Jan; 28(1):15.
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Pasciak AS, Bourgeois AC, Paxton BE, Nodit L, Coan PN, Kraitchman D, Stinnett SS, Patel VM, Fu Y, Adams JK, Tolbert MK, Lux CN, Arepally A, Bradley YC. Bariatric Radioembolization: A Pilot Study on Technical Feasibility and Safety in a Porcine Model. J Vasc Interv Radiol. 2016 Oct; 27(10):1509-17.
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Nadkarni GN, Rao V, Ismail-Beigi F, Fonseca VA, Shah SV, Simonson MS, Cantley L, Devarajan P, Parikh CR, Coca SG. Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial. Clin J Am Soc Nephrol. 2016 08 08; 11(8):1343-1352.
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Klair JS, Yang JD, Abdelmalek MF, Guy CD, Gill RM, Yates K, Unalp-Arida A, Lavine JE, Clark JM, Diehl AM, Suzuki A. A longer duration of estrogen deficiency increases fibrosis risk among postmenopausal women with nonalcoholic fatty liver disease. Hepatology. 2016 07; 64(1):85-91.
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Sharp CN, Doll MA, Dupre TV, Shah PP, Subathra M, Siow D, Arteel GE, Megyesi J, Beverly LJ, Siskind LJ. Repeated administration of low-dose cisplatin in mice induces fibrosis. Am J Physiol Renal Physiol. 2016 Mar 15; 310(6):F560-8.
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Schroder EA, Harfmann BD, Zhang X, Srikuea R, England JH, Hodge BA, Wen Y, Riley LA, Yu Q, Christie A, Smith JD, Seward T, Wolf Horrell EM, Mula J, Peterson CA, Butterfield TA, Esser KA. Intrinsic muscle clock is necessary for musculoskeletal health. J Physiol. 2015 Dec 15; 593(24):5387-404.
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Tkachenko E, Rawson R, La E, Doherty TA, Baum R, Cavagnero K, Miyanohara A, Dohil R, Kurten RC, Aceves SS. Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression. J Allergy Clin Immunol. 2016 Apr; 137(4):1270-1272.e1.
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Woo JS, Fishbein MC, Reemtsen B. Histologic examination of decellularized porcine intestinal submucosa extracellular matrix (CorMatrix) in pediatric congenital heart surgery. Cardiovasc Pathol. 2016 Jan-Feb; 25(1):12-7.
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