 Transfection
"Transfection" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
| Descriptor ID |
D014162
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| MeSH Number(s) |
E05.393.350.810 G05.355.760.860
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transfection".
Below are MeSH descriptors whose meaning is more specific than "Transfection".
This graph shows the total number of publications written about "Transfection" by people in UAMS Profiles by year, and whether "Transfection" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2020 | 0 | 4 | 4 | | 2018 | 0 | 3 | 3 | | 2017 | 0 | 5 | 5 | | 2016 | 0 | 6 | 6 | | 2015 | 0 | 7 | 7 | | 2014 | 2 | 5 | 7 | | 2013 | 0 | 9 | 9 | | 2012 | 1 | 10 | 11 | | 2011 | 0 | 10 | 10 | | 2010 | 1 | 13 | 14 | | 2009 | 0 | 15 | 15 | | 2008 | 2 | 16 | 18 | | 2007 | 0 | 18 | 18 | | 2006 | 0 | 15 | 15 | | 2005 | 0 | 23 | 23 | | 2004 | 0 | 21 | 21 | | 2003 | 0 | 24 | 24 | | 2002 | 0 | 15 | 15 | | 2001 | 1 | 12 | 13 | | 2000 | 0 | 12 | 12 | | 1999 | 0 | 13 | 13 | | 1998 | 0 | 5 | 5 | | 1997 | 0 | 8 | 8 | | 1996 | 1 | 7 | 8 | | 1995 | 0 | 4 | 4 | | 1994 | 0 | 5 | 5 | | 1993 | 0 | 3 | 3 | | 1992 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1990 | 1 | 1 | 2 | | 1989 | 0 | 3 | 3 |
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Below are the most recent publications written about "Transfection" by people in Profiles over the past ten years.
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Wolfe AR, Feng H, Zuniga O, Rodrigues H, Eldridge DE, Yang L, Shen C, Williams TM. RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers. Cancer Lett. 2024 Jun 01; 591:216873.
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Acharya B, Frett B. An updated patent review of rearranged during transfection (RET) kinase inhibitors (2016-present). Expert Opin Ther Pat. 2022 Oct; 32(10):1067-1077.
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Roane BM, Meza-Perez S, Katre AA, Goldsberry WN, Randall TD, Norian LA, Birrer MJ, Arend RC. Neutralization of TGF? Improves Tumor Immunity and Reduces Tumor Progression in Ovarian Carcinoma. Mol Cancer Ther. 2021 03; 20(3):602-611.
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Bhattarai D, Dad R, Worku T, Xu S, Ullah F, Zhang M, Liang X, Den T, Fan M, Zhang S. The functions and mechanisms of sequence differences of DGAT1 gene on milk fat synthesis between dairy cow and buffalo. J Dairy Res. 2020 May; 87(2):170-174.
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He Y, Li W, Lv D, Zhang X, Zhang X, Ortiz YT, Budamagunta V, Campisi J, Zheng G, Zhou D. Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. Aging Cell. 2020 03; 19(3):e13117.
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Li Z, Liu L, Du C, Yu Z, Yang Y, Xu J, Wei X, Zhan F, Lai Y, Qiu L, Hao M. Therapeutic effects of oligo-single-stranded DNA mimicking of hsa-miR-15a-5p on multiple myeloma. Cancer Gene Ther. 2020 12; 27(12):869-877.
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El Jamal SM, Grada Z, El Dinali MH, Zhou H, Hassan SY, Saad AG, Gibson B, Zhou X, Abulsayen HA, Khadra HS, Friedman J, Shalaby H, Kadi A, Megahed M, Emberesh M, Teruya-Feldstein J, Firpo-Betancourt A, Haikel Y, Fraig M, Hassan M. MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type. Lab Invest. 2019 04; 99(4):539-550.
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Nagalingam RS, Safi HA, Al-Hattab DS, Bagchi RA, Landry NM, Dixon IMC, Wigle JT, Czubryt MP. Regulation of cardiac fibroblast MMP2 gene expression by scleraxis. J Mol Cell Cardiol. 2018 07; 120:64-73.
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Hamdan H, Patyal P, Kockara NT, Wight PA. The wmN1 enhancer region in intron 1 is required for expression of human PLP1. Glia. 2018 08; 66(8):1763-1774.
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Yu D, Wu L, Gill P, Tolleson WH, Chen S, Sun J, Knox B, Jin Y, Xiao W, Hong H, Wang Y, Ren Z, Guo L, Mei N, Guo Y, Yang X, Shi L, Chen Y, Zeng L, Dreval K, Tryndyak V, Pogribny I, Fang H, Shi T, McCullough S, Bhattacharyya S, Schnackenberg L, Mattes W, Beger RD, James L, Tong W, Ning B. Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans. Arch Toxicol. 2018 Feb; 92(2):845-858.
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Wu X, Zhang LS, Toombs J, Kuo YC, Piazza JT, Tuladhar R, Barrett Q, Fan CW, Zhang X, Walensky LD, Kool M, Cheng SY, Brekken R, Opferman JT, Green DR, Moldoveanu T, Lum L. Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU?tumour suppressor. Nat Cell Biol. 2017 Oct; 19(10):1226-1236.
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Bagchi AK, Akolkar G, Mandal S, Ayyappan P, Yang X, Singal PK. Toll-like receptor 2 dominance over Toll-like receptor 4 in stressful conditions for its detrimental role in the heart. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1238-H1247.
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Dai Y, Cao Y, Zhang Z, Vallurupalli S, Mehta JL. Xanthine Oxidase Induces Foam Cell Formation through LOX-1 and NLRP3 Activation. Cardiovasc Drugs Ther. 2017 Feb; 31(1):19-27.
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McDaniel JM, Varley KE, Gertz J, Savic DS, Roberts BS, Bailey SK, Shevde LA, Ramaker RC, Lasseigne BN, Kirby MK, Newberry KM, Partridge EC, Jones AL, Boone B, Levy SE, Oliver PG, Sexton KC, Grizzle WE, Forero A, Buchsbaum DJ, Cooper SJ, Myers RM. Genomic regulation of invasion by STAT3 in triple negative breast cancer. Oncotarget. 2017 Jan 31; 8(5):8226-8238.
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Williams ED, Rogers SC, Zhang X, Azhar G, Wei JY. p49/STRAP, a Serum Response Factor Binding Protein (SRFBP1), Is Involved in the Redistribution of Cytoskeletal F-Actin Proteins during Glucose Deprivation. J Nutr Health Aging. 2017; 21(10):1142-1150.
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Millichap JJ, Miceli F, De Maria M, Keator C, Joshi N, Tran B, Soldovieri MV, Ambrosino P, Shashi V, Mikati MA, Cooper EC, Taglialatela M. Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant. Epilepsia. 2017 01; 58(1):e10-e15.
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Atluri K, Lee J, Seabold D, Elangovan S, Salem AK. Gene-Activated Titanium Surfaces Promote In Vitro Osteogenesis. Int J Oral Maxillofac Implants. 2017 Mar/Apr; 32(2):e83?e96.
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Li L, Piontek K, Ishida M, Fausther M, Dranoff JA, Fu R, Mezey E, Gould SJ, Fordjour FK, Meltzer SJ, Sirica AE, Selaru FM. Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. Hepatology. 2017 02; 65(2):501-514.
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Qin B, Wei T, Wang L, Ma N, Tang Q, Liang Y, Yang Z, Zhou L, Zhong R. Decreased expression of TIPE2 contributes to the hyperreactivity of monocyte to Toll-like receptor ligands in primary biliary cirrhosis. J Gastroenterol Hepatol. 2016 Jun; 31(6):1177-83.
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Joo JH, Wang B, Frankel E, Ge L, Xu L, Iyengar R, Li-Harms X, Wright C, Shaw TI, Lindsten T, Green DR, Peng J, Hendershot LM, Kilic F, Sze JY, Audhya A, Kundu M. The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis. Mol Cell. 2016 05 19; 62(4):491-506.
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Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 05 19; 62(4):558-71.
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Koss B, Ryan J, Budhraja A, Szarama K, Yang X, Bathina M, Cardone MH, Nikolovska-Coleska Z, Letai A, Opferman JT. Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines. Oncotarget. 2016 Mar 08; 7(10):11500-11.
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Atluri K, Seabold D, Hong L, Elangovan S, Salem AK. Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells. Mol Pharm. 2015 Aug 03; 12(8):3032-42.
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Bagchi RA, Mozolevska V, Abrenica B, Czubryt MP. Development of a high throughput luciferase reporter gene system for screening activators and repressors of human collagen Ia2 gene expression. Can J Physiol Pharmacol. 2015 Oct; 93(10):887-92.
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Chang WC, Wu SL, Huang WC, Hsu JY, Chan SH, Wang JM, Tsai JP, Chen BK. PTX3 gene activation in EGF-induced head and neck cancer cell metastasis. Oncotarget. 2015 Apr 10; 6(10):7741-57.
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Hamdan H, Kockara NT, Jolly LA, Haun S, Wight PA. Control of human PLP1 expression through transcriptional regulatory elements and alternatively spliced exons in intron 1. ASN Neuro. 2015 Jan-Feb; 7(1).
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Song KM, Choi MJ, Kwon MH, Ghatak K, Park SH, Ryu DS, Ryu JK, Suh JK. Optimizing in vivo gene transfer into mouse corpus cavernosum by use of surface electroporation. Korean J Urol. 2015 Mar; 56(3):197-204.
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Asakura M, Fujii H, Atsuda K, Itoh T, Fujiwara R. Dipeptidyl peptidase-4 greatly contributes to the hydrolysis of vildagliptin in human liver. Drug Metab Dispos. 2015 Apr; 43(4):477-84.
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Willett RA, Kudlyk TA, Lupashin VV. Expression of functional Myc-tagged conserved oligomeric Golgi (COG) subcomplexes in mammalian cells. Methods Mol Biol. 2015; 1270:167-77.
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Dates CR, Fahmi T, Pyrek SJ, Yao-Borengasser A, Borowa-Mazgaj B, Bratton SM, Kadlubar SA, Mackenzie PI, Haun RS, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines. Cancer Biol Ther. 2015; 16(5):714-23.
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