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Brendan Frett

Concepts (158)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
21
2025
204
5.140
Why?
Proto-Oncogene Proteins c-ret
11
2024
32
4.250
Why?
Drug Discovery
12
2025
84
3.360
Why?
Antineoplastic Agents
17
2025
1165
2.040
Why?
Pyridines
6
2021
130
1.170
Why?
Neoplasms
7
2021
1248
1.110
Why?
Drug Design
9
2021
119
1.010
Why?
Small Molecule Libraries
6
2021
67
1.010
Why?
Leukemia, Myeloid, Acute
2
2024
180
0.940
Why?
Molecular Structure
12
2025
293
0.900
Why?
Transforming Growth Factor beta
2
2022
134
0.900
Why?
Structure-Activity Relationship
13
2025
391
0.850
Why?
Cell Line, Tumor
18
2025
1393
0.850
Why?
Gene Rearrangement
1
2024
63
0.840
Why?
fms-Like Tyrosine Kinase 3
3
2021
16
0.810
Why?
Lung Neoplasms
3
2024
597
0.800
Why?
Aminoquinolines
1
2021
8
0.750
Why?
Receptor, trkA
4
2024
7
0.740
Why?
Adenine
1
2021
30
0.720
Why?
Pyrazoles
2
2021
111
0.710
Why?
Intracellular Signaling Peptides and Proteins
1
2021
134
0.700
Why?
Imidazoles
2
2018
125
0.680
Why?
Tumor Microenvironment
1
2022
221
0.670
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
30
0.650
Why?
Pyrimidines
5
2024
187
0.550
Why?
ras Proteins
2
2013
65
0.520
Why?
Dose-Response Relationship, Drug
7
2025
1369
0.510
Why?
Computer-Aided Design
1
2015
22
0.470
Why?
Humans
33
2025
50419
0.440
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.430
Why?
Proto-Oncogene Proteins
2
2013
150
0.430
Why?
Acetamides
2
2025
19
0.420
Why?
Quinazolines
2
2025
33
0.410
Why?
Cell Proliferation
9
2025
980
0.400
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
90
0.390
Why?
HEK293 Cells
4
2021
209
0.380
Why?
Models, Molecular
4
2020
333
0.350
Why?
Receptor, trkB
2
2021
6
0.330
Why?
Animals
13
2025
13063
0.320
Why?
Molecular Conformation
3
2019
66
0.300
Why?
Signal Transduction
5
2022
1608
0.260
Why?
Drug Screening Assays, Antitumor
6
2025
129
0.260
Why?
Mice
8
2025
5659
0.250
Why?
Molecular Docking Simulation
3
2021
71
0.240
Why?
Chromones
1
2024
17
0.230
Why?
Solubility
1
2024
71
0.230
Why?
DNA-Activated Protein Kinase
1
2024
21
0.220
Why?
Morpholines
1
2024
64
0.220
Why?
Phosphorylation
4
2021
520
0.220
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.220
Why?
Proto-Oncogenes
1
2024
27
0.220
Why?
NIH 3T3 Cells
3
2021
51
0.210
Why?
Lymphoma
1
2024
66
0.210
Why?
Mutation
4
2022
1275
0.200
Why?
Patents as Topic
1
2022
9
0.200
Why?
Drug Evaluation, Preclinical
3
2021
144
0.200
Why?
CARD Signaling Adaptor Proteins
1
2022
5
0.200
Why?
Chemistry Techniques, Synthetic
3
2020
20
0.200
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
153
0.190
Why?
Transfection
1
2022
353
0.190
Why?
Clinical Trials as Topic
2
2021
488
0.190
Why?
Indoles
1
2024
277
0.180
Why?
Phthalazines
1
2021
20
0.180
Why?
Thiophenes
1
2021
36
0.180
Why?
Cell Line
3
2021
997
0.170
Why?
Aziridines
1
2020
2
0.170
Why?
Pyrroles
1
2020
68
0.170
Why?
Maleimides
1
2020
8
0.170
Why?
Protein Interaction Mapping
1
2020
37
0.170
Why?
Ketones
1
2019
9
0.160
Why?
Molecular Dynamics Simulation
1
2019
34
0.160
Why?
Phosphoproteins
1
2020
116
0.160
Why?
Oxidative Stress
1
2024
770
0.160
Why?
Adenosine Triphosphate
1
2020
230
0.160
Why?
Apoptosis
3
2022
1092
0.160
Why?
Oligopeptides
1
2019
94
0.160
Why?
Decarboxylation
1
2018
3
0.160
Why?
Receptor, trkC
1
2018
4
0.150
Why?
Metabolome
1
2019
94
0.150
Why?
Models, Chemical
1
2018
64
0.150
Why?
Mice, Nude
2
2017
247
0.150
Why?
Isoquinolines
1
2018
28
0.150
Why?
Computational Biology
1
2020
194
0.150
Why?
Bone Marrow
1
2020
360
0.150
Why?
Benzimidazoles
1
2018
49
0.150
Why?
Proto-Oncogene Proteins c-kit
1
2018
33
0.140
Why?
Software
1
2020
268
0.140
Why?
Heterocyclic Compounds
1
2018
29
0.140
Why?
Boronic Acids
1
2018
182
0.140
Why?
Ligands
2
2015
203
0.140
Why?
Proteomics
1
2020
313
0.140
Why?
Nitrazepam
1
2016
1
0.140
Why?
Glioblastoma
1
2017
94
0.130
Why?
Libraries, Digital
1
2015
2
0.120
Why?
Molecular Weight
1
2015
82
0.120
Why?
Carboxylic Acids
1
2015
17
0.120
Why?
Colorectal Neoplasms
1
2018
256
0.120
Why?
Human Umbilical Vein Endothelial Cells
1
2015
90
0.120
Why?
Palladium
1
2014
4
0.110
Why?
Brain Neoplasms
1
2017
281
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
19
0.110
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
67
0.100
Why?
Molecular Targeted Therapy
1
2013
122
0.100
Why?
Drug Resistance, Neoplasm
1
2013
315
0.090
Why?
Cells, Cultured
1
2014
1563
0.090
Why?
Cell Survival
2
2021
587
0.080
Why?
Mice, Inbred BALB C
2
2020
293
0.080
Why?
Protein Binding
2
2020
648
0.070
Why?
Rats
2
2025
3262
0.060
Why?
Neoplasms, Experimental
1
2025
111
0.060
Why?
Administration, Oral
1
2025
438
0.050
Why?
DNA Damage
1
2024
299
0.050
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
T-Lymphocytes
1
2024
325
0.050
Why?
Furans
1
2022
27
0.050
Why?
Oncogenes
1
2022
54
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
82
0.050
Why?
Receptors, Transforming Growth Factor beta
1
2021
25
0.050
Why?
Smad Proteins
1
2021
11
0.050
Why?
Tumor Cells, Cultured
1
2022
453
0.040
Why?
Blood-Brain Barrier
1
2021
47
0.040
Why?
Wound Healing
1
2022
183
0.040
Why?
Binding, Competitive
1
2020
93
0.040
Why?
Amino Acid Motifs
1
2020
55
0.040
Why?
Hematopoiesis
1
2020
72
0.040
Why?
Workflow
1
2020
50
0.040
Why?
Binding Sites
1
2021
362
0.040
Why?
Xenopus laevis
1
2019
43
0.040
Why?
Databases, Genetic
1
2020
77
0.040
Why?
Protein Structure, Secondary
1
2019
71
0.040
Why?
Ethanol
1
2022
336
0.040
Why?
Stereoisomerism
1
2019
104
0.040
Why?
Cell Movement
1
2020
244
0.040
Why?
Mass Spectrometry
1
2020
285
0.040
Why?
Catalytic Domain
1
2018
57
0.040
Why?
Cell Cycle Checkpoints
1
2018
29
0.040
Why?
Female
4
2020
27053
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Neoplasm Transplantation
1
2017
83
0.030
Why?
Enzyme Activation
1
2018
268
0.030
Why?
Gene Silencing
1
2017
114
0.030
Why?
M Phase Cell Cycle Checkpoints
1
2016
4
0.030
Why?
Polyploidy
1
2016
11
0.030
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
9
0.030
Why?
Neoplastic Stem Cells
1
2017
97
0.030
Why?
Protein Conformation
1
2016
163
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
210
0.030
Why?
Hydrazines
1
2015
17
0.030
Why?
Solvents
1
2015
29
0.030
Why?
Metals
1
2015
34
0.030
Why?
Carbon
1
2015
54
0.030
Why?
Rats, Sprague-Dawley
1
2018
1556
0.030
Why?
Microwaves
1
2014
10
0.030
Why?
Catalysis
1
2014
90
0.030
Why?
Kinetics
1
2015
634
0.030
Why?
Cell Cycle Proteins
1
2013
163
0.020
Why?
Models, Biological
1
2013
717
0.020
Why?
Male
2
2020
25866
0.020
Why?
Frett's Networks
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