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Brendan Frett

Concepts (156)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
20
2024
204
5.010
Why?
Proto-Oncogene Proteins c-ret
11
2024
33
4.320
Why?
Drug Discovery
11
2024
85
3.190
Why?
Antineoplastic Agents
16
2024
1172
1.920
Why?
Pyridines
6
2021
131
1.200
Why?
Neoplasms
7
2021
1251
1.120
Why?
Drug Design
9
2021
119
1.030
Why?
Small Molecule Libraries
6
2021
67
1.030
Why?
Leukemia, Myeloid, Acute
2
2024
181
0.950
Why?
Transforming Growth Factor beta
2
2022
136
0.910
Why?
Molecular Structure
11
2024
296
0.860
Why?
Gene Rearrangement
1
2024
65
0.860
Why?
fms-Like Tyrosine Kinase 3
3
2021
16
0.820
Why?
Cell Line, Tumor
17
2024
1398
0.810
Why?
Lung Neoplasms
3
2024
601
0.810
Why?
Structure-Activity Relationship
12
2024
395
0.810
Why?
Aminoquinolines
1
2021
7
0.760
Why?
Receptor, trkA
4
2024
7
0.760
Why?
Adenine
1
2021
31
0.730
Why?
Pyrazoles
2
2021
111
0.720
Why?
Intracellular Signaling Peptides and Proteins
1
2021
135
0.710
Why?
Imidazoles
2
2018
127
0.690
Why?
Tumor Microenvironment
1
2022
222
0.680
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
30
0.670
Why?
Pyrimidines
5
2024
191
0.560
Why?
ras Proteins
2
2013
64
0.530
Why?
Computer-Aided Design
1
2015
22
0.480
Why?
Dose-Response Relationship, Drug
6
2021
1372
0.470
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.440
Why?
Proto-Oncogene Proteins
2
2013
145
0.440
Why?
Humans
32
2024
50503
0.430
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
90
0.390
Why?
HEK293 Cells
4
2021
213
0.390
Why?
Cell Proliferation
8
2022
985
0.360
Why?
Models, Molecular
4
2020
334
0.360
Why?
Receptor, trkB
2
2021
6
0.340
Why?
Molecular Conformation
3
2019
66
0.310
Why?
Animals
12
2024
13124
0.310
Why?
Signal Transduction
5
2022
1624
0.270
Why?
Molecular Docking Simulation
3
2021
73
0.240
Why?
Chromones
1
2024
18
0.230
Why?
Solubility
1
2024
71
0.230
Why?
DNA-Activated Protein Kinase
1
2024
22
0.230
Why?
Morpholines
1
2024
66
0.230
Why?
Phosphorylation
4
2021
525
0.220
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.220
Why?
Proto-Oncogenes
1
2024
27
0.220
Why?
Mice
7
2024
5687
0.220
Why?
NIH 3T3 Cells
3
2021
51
0.210
Why?
Lymphoma
1
2024
67
0.210
Why?
Patents as Topic
1
2022
9
0.210
Why?
Mutation
4
2022
1280
0.210
Why?
Drug Evaluation, Preclinical
3
2021
145
0.200
Why?
CARD Signaling Adaptor Proteins
1
2022
5
0.200
Why?
Drug Screening Assays, Antitumor
5
2021
131
0.200
Why?
Chemistry Techniques, Synthetic
3
2020
20
0.200
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
154
0.190
Why?
Transfection
1
2022
356
0.190
Why?
Clinical Trials as Topic
2
2021
486
0.190
Why?
Indoles
1
2024
278
0.190
Why?
Phthalazines
1
2021
20
0.190
Why?
Thiophenes
1
2021
36
0.190
Why?
Acetamides
1
2021
18
0.180
Why?
Quinazolines
1
2020
32
0.170
Why?
Cell Line
3
2021
988
0.170
Why?
Aziridines
1
2020
2
0.170
Why?
Pyrroles
1
2020
68
0.170
Why?
Maleimides
1
2020
8
0.170
Why?
Protein Interaction Mapping
1
2020
37
0.170
Why?
Ketones
1
2019
9
0.170
Why?
Molecular Dynamics Simulation
1
2019
34
0.170
Why?
Phosphoproteins
1
2020
115
0.160
Why?
Oxidative Stress
1
2024
772
0.160
Why?
Adenosine Triphosphate
1
2020
232
0.160
Why?
Oligopeptides
1
2019
95
0.160
Why?
Decarboxylation
1
2018
3
0.160
Why?
Apoptosis
3
2022
1097
0.160
Why?
Receptor, trkC
1
2018
4
0.160
Why?
Metabolome
1
2019
94
0.160
Why?
Models, Chemical
1
2018
64
0.150
Why?
Isoquinolines
1
2018
25
0.150
Why?
Mice, Nude
2
2017
248
0.150
Why?
Bone Marrow
1
2020
363
0.150
Why?
Computational Biology
1
2020
215
0.150
Why?
Benzimidazoles
1
2018
48
0.150
Why?
Proto-Oncogene Proteins c-kit
1
2018
34
0.150
Why?
Software
1
2020
276
0.150
Why?
Heterocyclic Compounds
1
2018
29
0.150
Why?
Boronic Acids
1
2018
183
0.150
Why?
Ligands
2
2015
203
0.140
Why?
Proteomics
1
2020
314
0.140
Why?
Nitrazepam
1
2016
1
0.140
Why?
Glioblastoma
1
2017
94
0.130
Why?
Libraries, Digital
1
2015
2
0.120
Why?
Molecular Weight
1
2015
82
0.120
Why?
Carboxylic Acids
1
2015
17
0.120
Why?
Colorectal Neoplasms
1
2018
260
0.120
Why?
Human Umbilical Vein Endothelial Cells
1
2015
90
0.120
Why?
Palladium
1
2014
4
0.120
Why?
Brain Neoplasms
1
2017
291
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
20
0.110
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
67
0.110
Why?
Molecular Targeted Therapy
1
2013
123
0.100
Why?
Drug Resistance, Neoplasm
1
2013
316
0.090
Why?
Cells, Cultured
1
2014
1571
0.090
Why?
Cell Survival
2
2021
589
0.080
Why?
Mice, Inbred BALB C
2
2020
296
0.080
Why?
Protein Binding
2
2020
654
0.080
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
DNA Damage
1
2024
301
0.050
Why?
Furans
1
2022
27
0.050
Why?
Oncogenes
1
2022
57
0.050
Why?
T-Lymphocytes
1
2024
325
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
82
0.050
Why?
Receptors, Transforming Growth Factor beta
1
2021
25
0.050
Why?
Smad Proteins
1
2021
11
0.050
Why?
Tumor Cells, Cultured
1
2022
457
0.050
Why?
Blood-Brain Barrier
1
2021
47
0.040
Why?
Wound Healing
1
2022
186
0.040
Why?
Binding, Competitive
1
2020
94
0.040
Why?
Amino Acid Motifs
1
2020
55
0.040
Why?
Hematopoiesis
1
2020
72
0.040
Why?
Workflow
1
2020
50
0.040
Why?
Binding Sites
1
2021
362
0.040
Why?
Xenopus laevis
1
2019
39
0.040
Why?
Protein Structure, Secondary
1
2019
71
0.040
Why?
Databases, Genetic
1
2020
88
0.040
Why?
Ethanol
1
2022
336
0.040
Why?
Stereoisomerism
1
2019
104
0.040
Why?
Cell Movement
1
2020
247
0.040
Why?
Mass Spectrometry
1
2020
285
0.040
Why?
Catalytic Domain
1
2018
58
0.040
Why?
Cell Cycle Checkpoints
1
2018
29
0.040
Why?
Female
4
2020
27081
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Neoplasm Transplantation
1
2017
86
0.040
Why?
Enzyme Activation
1
2018
268
0.040
Why?
Gene Silencing
1
2017
115
0.030
Why?
M Phase Cell Cycle Checkpoints
1
2016
4
0.030
Why?
Polyploidy
1
2016
11
0.030
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
9
0.030
Why?
Neoplastic Stem Cells
1
2017
98
0.030
Why?
Protein Conformation
1
2016
162
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
212
0.030
Why?
Hydrazines
1
2015
16
0.030
Why?
Solvents
1
2015
29
0.030
Why?
Metals
1
2015
35
0.030
Why?
Carbon
1
2015
55
0.030
Why?
Rats, Sprague-Dawley
1
2018
1585
0.030
Why?
Microwaves
1
2014
10
0.030
Why?
Catalysis
1
2014
89
0.030
Why?
Kinetics
1
2015
623
0.030
Why?
Cell Cycle Proteins
1
2013
161
0.020
Why?
Rats
1
2016
3292
0.020
Why?
Models, Biological
1
2013
716
0.020
Why?
Male
2
2020
25907
0.020
Why?
Frett's Networks
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