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Brendan Frett

Concepts (163)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
23
2025
227
6.010
Why?
Proto-Oncogene Proteins c-ret
12
2025
33
5.150
Why?
Drug Discovery
12
2025
93
3.330
Why?
Antineoplastic Agents
18
2025
1222
2.510
Why?
Neoplasms
8
2025
1325
1.540
Why?
Pyridines
6
2021
132
1.160
Why?
Drug Design
9
2021
120
1.010
Why?
Small Molecule Libraries
6
2021
67
1.000
Why?
Leukemia, Myeloid, Acute
2
2024
203
0.910
Why?
Transforming Growth Factor beta
2
2022
138
0.890
Why?
Molecular Structure
12
2025
314
0.890
Why?
Structure-Activity Relationship
13
2025
404
0.850
Why?
Gene Rearrangement
1
2024
75
0.830
Why?
Cell Line, Tumor
18
2025
1470
0.830
Why?
fms-Like Tyrosine Kinase 3
3
2021
20
0.800
Why?
Lung Neoplasms
3
2024
636
0.770
Why?
Aminoquinolines
1
2021
8
0.740
Why?
Receptor, trkA
4
2024
7
0.740
Why?
Adenine
1
2021
31
0.710
Why?
Pyrazoles
2
2021
114
0.700
Why?
Intracellular Signaling Peptides and Proteins
1
2021
134
0.700
Why?
Imidazoles
2
2018
124
0.680
Why?
Tumor Microenvironment
1
2022
256
0.660
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
30
0.650
Why?
Pyrimidines
5
2024
199
0.550
Why?
ras Proteins
2
2013
64
0.510
Why?
Dose-Response Relationship, Drug
7
2025
1378
0.510
Why?
Computer-Aided Design
1
2015
20
0.470
Why?
Humans
34
2025
52483
0.470
Why?
Patents as Topic
2
2025
10
0.440
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.430
Why?
Proto-Oncogene Proteins
2
2013
151
0.430
Why?
Animals
15
2025
13505
0.420
Why?
Acetamides
2
2025
19
0.420
Why?
Quinazolines
2
2025
34
0.410
Why?
Cell Proliferation
9
2025
1023
0.400
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
106
0.380
Why?
HEK293 Cells
4
2021
229
0.380
Why?
Models, Molecular
4
2020
348
0.350
Why?
Receptor, trkB
2
2021
6
0.330
Why?
Molecular Conformation
3
2019
70
0.300
Why?
Drug Resistance, Neoplasm
2
2025
326
0.290
Why?
Receptors, Transforming Growth Factor beta
2
2025
29
0.290
Why?
Mice
9
2025
5949
0.270
Why?
Signal Transduction
5
2022
1671
0.260
Why?
Drug Screening Assays, Antitumor
6
2025
136
0.250
Why?
Molecular Docking Simulation
3
2021
88
0.240
Why?
Ureteral Obstruction
1
2025
62
0.230
Why?
Chromones
1
2024
17
0.230
Why?
DNA-Activated Protein Kinase
1
2024
21
0.220
Why?
Solubility
1
2024
79
0.220
Why?
Morpholines
1
2024
66
0.220
Why?
Phosphorylation
4
2021
528
0.220
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.220
Why?
Proto-Oncogenes
1
2024
27
0.220
Why?
NIH 3T3 Cells
3
2021
51
0.210
Why?
Lymphoma
1
2024
71
0.210
Why?
Kidney Diseases
1
2025
220
0.200
Why?
Drug Evaluation, Preclinical
3
2021
146
0.200
Why?
Mutation
4
2022
1347
0.200
Why?
CARD Signaling Adaptor Proteins
1
2022
6
0.200
Why?
Chemistry Techniques, Synthetic
3
2020
21
0.200
Why?
Transfection
1
2022
357
0.190
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
170
0.190
Why?
Clinical Trials as Topic
2
2021
467
0.190
Why?
Indoles
1
2024
278
0.180
Why?
Phthalazines
1
2021
20
0.180
Why?
Thiophenes
1
2021
38
0.180
Why?
Kidney
1
2025
707
0.170
Why?
Cell Line
3
2021
1030
0.170
Why?
Aziridines
1
2020
1
0.170
Why?
Pyrroles
1
2020
71
0.170
Why?
Maleimides
1
2020
8
0.170
Why?
Protein Interaction Mapping
1
2020
37
0.170
Why?
Ketones
1
2019
9
0.160
Why?
Molecular Dynamics Simulation
1
2019
44
0.160
Why?
Phosphoproteins
1
2020
119
0.160
Why?
Adenosine Triphosphate
1
2020
205
0.160
Why?
Oligopeptides
1
2019
92
0.160
Why?
Oxidative Stress
1
2024
807
0.160
Why?
Apoptosis
3
2022
1119
0.150
Why?
Decarboxylation
1
2018
3
0.150
Why?
Receptor, trkC
1
2018
4
0.150
Why?
Metabolome
1
2019
101
0.150
Why?
Models, Chemical
1
2018
66
0.150
Why?
Isoquinolines
1
2018
24
0.150
Why?
Mice, Nude
2
2017
265
0.150
Why?
Bone Marrow
1
2020
364
0.150
Why?
Computational Biology
1
2020
212
0.150
Why?
Proto-Oncogene Proteins c-kit
1
2018
33
0.140
Why?
Benzimidazoles
1
2018
49
0.140
Why?
Software
1
2020
280
0.140
Why?
Heterocyclic Compounds
1
2018
28
0.140
Why?
Boronic Acids
1
2018
183
0.140
Why?
Ligands
2
2015
206
0.140
Why?
Proteomics
1
2020
329
0.140
Why?
Nitrazepam
1
2016
1
0.140
Why?
Glioblastoma
1
2017
97
0.120
Why?
Libraries, Digital
1
2015
2
0.120
Why?
Molecular Weight
1
2015
82
0.120
Why?
Carboxylic Acids
1
2015
18
0.120
Why?
Human Umbilical Vein Endothelial Cells
1
2015
99
0.110
Why?
Colorectal Neoplasms
1
2018
294
0.110
Why?
Palladium
1
2014
4
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
21
0.110
Why?
Brain Neoplasms
1
2017
291
0.110
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
69
0.100
Why?
Molecular Targeted Therapy
1
2013
133
0.100
Why?
Cells, Cultured
1
2014
1567
0.090
Why?
Cell Survival
2
2021
612
0.080
Why?
Mice, Inbred BALB C
2
2020
312
0.080
Why?
Protein Binding
2
2020
667
0.070
Why?
Rats
2
2025
3220
0.060
Why?
Neoplasms, Experimental
1
2025
114
0.060
Why?
Fibrosis
1
2025
196
0.060
Why?
Administration, Oral
1
2025
451
0.050
Why?
Female
5
2025
28171
0.050
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
DNA Damage
1
2024
305
0.050
Why?
Oncogenes
1
2022
60
0.050
Why?
T-Lymphocytes
1
2024
340
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
86
0.050
Why?
Furans
1
2022
30
0.050
Why?
Smad Proteins
1
2021
12
0.050
Why?
Tumor Cells, Cultured
1
2022
460
0.040
Why?
Blood-Brain Barrier
1
2021
48
0.040
Why?
Binding, Competitive
1
2020
90
0.040
Why?
Amino Acid Motifs
1
2020
57
0.040
Why?
Wound Healing
1
2022
219
0.040
Why?
Hematopoiesis
1
2020
69
0.040
Why?
Workflow
1
2020
51
0.040
Why?
Binding Sites
1
2021
377
0.040
Why?
Xenopus laevis
1
2019
40
0.040
Why?
Databases, Genetic
1
2020
83
0.040
Why?
Protein Structure, Secondary
1
2019
71
0.040
Why?
Mice, Inbred C57BL
1
2025
1884
0.040
Why?
Ethanol
1
2022
342
0.040
Why?
Stereoisomerism
1
2019
101
0.040
Why?
Cell Movement
1
2020
268
0.040
Why?
Mass Spectrometry
1
2020
292
0.040
Why?
Catalytic Domain
1
2018
60
0.040
Why?
Cell Cycle Checkpoints
1
2018
32
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Enzyme Activation
1
2018
270
0.030
Why?
Neoplasm Transplantation
1
2017
87
0.030
Why?
Gene Silencing
1
2017
118
0.030
Why?
Polyploidy
1
2016
9
0.030
Why?
M Phase Cell Cycle Checkpoints
1
2016
5
0.030
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
9
0.030
Why?
Male
3
2025
26761
0.030
Why?
Neoplastic Stem Cells
1
2017
99
0.030
Why?
Protein Conformation
1
2016
176
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
220
0.030
Why?
Hydrazines
1
2015
17
0.030
Why?
Solvents
1
2015
33
0.030
Why?
Metals
1
2015
36
0.030
Why?
Carbon
1
2015
55
0.030
Why?
Rats, Sprague-Dawley
1
2018
1563
0.030
Why?
Microwaves
1
2014
11
0.030
Why?
Catalysis
1
2014
88
0.030
Why?
Kinetics
1
2015
626
0.030
Why?
Cell Cycle Proteins
1
2013
169
0.020
Why?
Models, Biological
1
2013
735
0.020
Why?
Frett's Networks
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