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Brendan Frett

Concepts (163)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
23
2025
233
5.710
Why?
Proto-Oncogene Proteins c-ret
12
2025
33
4.910
Why?
Drug Discovery
12
2025
94
3.180
Why?
Antineoplastic Agents
18
2025
1232
2.420
Why?
Neoplasms
8
2025
1334
1.480
Why?
Pyridines
6
2021
135
1.110
Why?
Drug Design
9
2021
121
0.960
Why?
Small Molecule Libraries
6
2021
66
0.960
Why?
Leukemia, Myeloid, Acute
2
2024
208
0.870
Why?
Transforming Growth Factor beta
2
2022
136
0.850
Why?
Molecular Structure
12
2025
320
0.850
Why?
Structure-Activity Relationship
13
2025
396
0.810
Why?
Cell Line, Tumor
18
2025
1470
0.800
Why?
Gene Rearrangement
1
2024
76
0.790
Why?
fms-Like Tyrosine Kinase 3
3
2021
20
0.760
Why?
Lung Neoplasms
3
2024
645
0.740
Why?
Aminoquinolines
1
2021
8
0.710
Why?
Receptor, trkA
4
2024
7
0.710
Why?
Adenine
1
2021
29
0.680
Why?
Pyrazoles
2
2021
123
0.660
Why?
Intracellular Signaling Peptides and Proteins
1
2021
136
0.660
Why?
Imidazoles
2
2018
114
0.650
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
38
0.620
Why?
Tumor Microenvironment
1
2022
274
0.620
Why?
Pyrimidines
5
2024
205
0.520
Why?
ras Proteins
2
2013
64
0.490
Why?
Dose-Response Relationship, Drug
7
2025
1367
0.490
Why?
Computer-Aided Design
1
2015
20
0.450
Why?
Humans
34
2025
53230
0.450
Why?
Patents as Topic
2
2025
10
0.420
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.410
Why?
Proto-Oncogene Proteins
2
2013
150
0.410
Why?
Animals
15
2025
13526
0.400
Why?
Acetamides
2
2025
19
0.400
Why?
Quinazolines
2
2025
34
0.390
Why?
Cell Proliferation
9
2025
1031
0.380
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
110
0.360
Why?
HEK293 Cells
4
2021
235
0.360
Why?
Models, Molecular
4
2020
352
0.340
Why?
Receptor, trkB
2
2021
8
0.320
Why?
Molecular Conformation
3
2019
66
0.290
Why?
Receptors, Transforming Growth Factor beta
2
2025
29
0.270
Why?
Drug Resistance, Neoplasm
2
2025
350
0.270
Why?
Mice
9
2025
5982
0.260
Why?
Signal Transduction
5
2022
1748
0.240
Why?
Drug Screening Assays, Antitumor
6
2025
136
0.240
Why?
Molecular Docking Simulation
3
2021
93
0.220
Why?
Ureteral Obstruction
1
2025
62
0.220
Why?
Chromones
1
2024
16
0.220
Why?
Solubility
1
2024
83
0.210
Why?
DNA-Activated Protein Kinase
1
2024
24
0.210
Why?
Morpholines
1
2024
64
0.210
Why?
Phosphorylation
4
2021
533
0.210
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.210
Why?
Proto-Oncogenes
1
2024
27
0.210
Why?
NIH 3T3 Cells
3
2021
52
0.200
Why?
Lymphoma
1
2024
71
0.200
Why?
Drug Evaluation, Preclinical
3
2021
142
0.190
Why?
Kidney Diseases
1
2025
230
0.190
Why?
Mutation
4
2022
1337
0.190
Why?
CARD Signaling Adaptor Proteins
1
2022
6
0.190
Why?
Chemistry Techniques, Synthetic
3
2020
21
0.190
Why?
Clinical Trials as Topic
2
2021
466
0.180
Why?
Transfection
1
2022
359
0.180
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
175
0.180
Why?
Indoles
1
2024
280
0.170
Why?
Phthalazines
1
2021
20
0.170
Why?
Thiophenes
1
2021
45
0.170
Why?
Kidney
1
2025
715
0.160
Why?
Cell Line
3
2021
1016
0.160
Why?
Aziridines
1
2020
1
0.160
Why?
Pyrroles
1
2020
73
0.160
Why?
Maleimides
1
2020
8
0.160
Why?
Protein Interaction Mapping
1
2020
38
0.160
Why?
Ketones
1
2019
10
0.160
Why?
Molecular Dynamics Simulation
1
2019
44
0.150
Why?
Phosphoproteins
1
2020
117
0.150
Why?
Adenosine Triphosphate
1
2020
211
0.150
Why?
Oxidative Stress
1
2024
819
0.150
Why?
Apoptosis
3
2022
1139
0.150
Why?
Oligopeptides
1
2019
94
0.150
Why?
Decarboxylation
1
2018
3
0.150
Why?
Receptor, trkC
1
2018
4
0.150
Why?
Metabolome
1
2019
107
0.140
Why?
Mice, Nude
2
2017
232
0.140
Why?
Models, Chemical
1
2018
65
0.140
Why?
Isoquinolines
1
2018
22
0.140
Why?
Bone Marrow
1
2020
359
0.140
Why?
Computational Biology
1
2020
209
0.140
Why?
Benzimidazoles
1
2018
50
0.140
Why?
Proto-Oncogene Proteins c-kit
1
2018
34
0.140
Why?
Boronic Acids
1
2018
180
0.140
Why?
Software
1
2020
280
0.140
Why?
Heterocyclic Compounds
1
2018
30
0.140
Why?
Ligands
2
2015
203
0.130
Why?
Proteomics
1
2020
336
0.130
Why?
Nitrazepam
1
2016
1
0.130
Why?
Glioblastoma
1
2017
101
0.120
Why?
Libraries, Digital
1
2015
2
0.110
Why?
Molecular Weight
1
2015
77
0.110
Why?
Carboxylic Acids
1
2015
18
0.110
Why?
Human Umbilical Vein Endothelial Cells
1
2015
102
0.110
Why?
Palladium
1
2014
4
0.110
Why?
Colorectal Neoplasms
1
2018
302
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
21
0.100
Why?
Brain Neoplasms
1
2017
319
0.100
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
69
0.100
Why?
Molecular Targeted Therapy
1
2013
138
0.090
Why?
Cells, Cultured
1
2014
1569
0.080
Why?
Cell Survival
2
2021
600
0.070
Why?
Mice, Inbred BALB C
2
2020
310
0.070
Why?
Protein Binding
2
2020
670
0.070
Why?
Rats
2
2025
3162
0.060
Why?
Neoplasms, Experimental
1
2025
112
0.050
Why?
Fibrosis
1
2025
198
0.050
Why?
Administration, Oral
1
2025
456
0.050
Why?
DNA Damage
1
2024
309
0.050
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
Female
5
2025
28782
0.050
Why?
T-Lymphocytes
1
2024
321
0.050
Why?
Oncogenes
1
2022
61
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
85
0.050
Why?
Furans
1
2022
30
0.050
Why?
Smad Proteins
1
2021
16
0.040
Why?
Tumor Cells, Cultured
1
2022
441
0.040
Why?
Blood-Brain Barrier
1
2021
51
0.040
Why?
Binding, Competitive
1
2020
89
0.040
Why?
Amino Acid Motifs
1
2020
59
0.040
Why?
Hematopoiesis
1
2020
69
0.040
Why?
Wound Healing
1
2022
226
0.040
Why?
Workflow
1
2020
53
0.040
Why?
Binding Sites
1
2021
373
0.040
Why?
Xenopus laevis
1
2019
44
0.040
Why?
Databases, Genetic
1
2020
82
0.040
Why?
Ethanol
1
2022
338
0.040
Why?
Mice, Inbred C57BL
1
2025
1925
0.040
Why?
Protein Structure, Secondary
1
2019
71
0.040
Why?
Stereoisomerism
1
2019
101
0.040
Why?
Cell Movement
1
2020
279
0.040
Why?
Mass Spectrometry
1
2020
294
0.040
Why?
Catalytic Domain
1
2018
60
0.040
Why?
Cell Cycle Checkpoints
1
2018
32
0.030
Why?
Aza Compounds
1
2018
14
0.030
Why?
Enzyme Activation
1
2018
267
0.030
Why?
Neoplasm Transplantation
1
2017
86
0.030
Why?
Gene Silencing
1
2017
122
0.030
Why?
Polyploidy
1
2016
9
0.030
Why?
M Phase Cell Cycle Checkpoints
1
2016
5
0.030
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
9
0.030
Why?
Male
3
2025
27435
0.030
Why?
Neoplastic Stem Cells
1
2017
90
0.030
Why?
Protein Conformation
1
2016
174
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
228
0.030
Why?
Hydrazines
1
2015
19
0.030
Why?
Solvents
1
2015
32
0.030
Why?
Metals
1
2015
37
0.030
Why?
Rats, Sprague-Dawley
1
2018
1544
0.030
Why?
Carbon
1
2015
60
0.030
Why?
Microwaves
1
2014
10
0.030
Why?
Catalysis
1
2014
87
0.030
Why?
Kinetics
1
2015
607
0.030
Why?
Cell Cycle Proteins
1
2013
170
0.020
Why?
Models, Biological
1
2013
737
0.020
Why?
Frett's Networks
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