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Brendan Frett

Concepts (156)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
20
2024
204
5.160
Why?
Proto-Oncogene Proteins c-ret
11
2024
33
4.500
Why?
Drug Discovery
11
2024
85
3.320
Why?
Antineoplastic Agents
16
2024
1171
1.990
Why?
Pyridines
6
2021
130
1.240
Why?
Neoplasms
7
2021
1235
1.170
Why?
Drug Design
9
2021
120
1.070
Why?
Small Molecule Libraries
6
2021
68
1.070
Why?
Leukemia, Myeloid, Acute
2
2024
185
0.980
Why?
Transforming Growth Factor beta
2
2022
144
0.940
Why?
Molecular Structure
11
2024
297
0.890
Why?
Gene Rearrangement
1
2024
74
0.890
Why?
fms-Like Tyrosine Kinase 3
3
2021
16
0.860
Why?
Structure-Activity Relationship
12
2024
395
0.840
Why?
Cell Line, Tumor
17
2024
1403
0.840
Why?
Lung Neoplasms
3
2024
606
0.840
Why?
Aminoquinolines
1
2021
7
0.790
Why?
Receptor, trkA
4
2024
7
0.790
Why?
Adenine
1
2021
32
0.760
Why?
Pyrazoles
2
2021
113
0.750
Why?
Intracellular Signaling Peptides and Proteins
1
2021
142
0.740
Why?
Imidazoles
2
2018
119
0.720
Why?
Tumor Microenvironment
1
2022
212
0.720
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
32
0.690
Why?
Pyrimidines
5
2024
192
0.580
Why?
ras Proteins
2
2013
64
0.550
Why?
Computer-Aided Design
1
2015
21
0.500
Why?
Dose-Response Relationship, Drug
6
2021
1376
0.490
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.460
Why?
Proto-Oncogene Proteins
2
2013
149
0.450
Why?
Humans
32
2024
49974
0.450
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
105
0.400
Why?
HEK293 Cells
4
2021
222
0.400
Why?
Models, Molecular
4
2020
338
0.370
Why?
Cell Proliferation
8
2022
1007
0.370
Why?
Receptor, trkB
2
2021
6
0.350
Why?
Molecular Conformation
3
2019
67
0.320
Why?
Animals
12
2024
13187
0.310
Why?
Signal Transduction
5
2022
1618
0.280
Why?
Molecular Docking Simulation
3
2021
73
0.250
Why?
Chromones
1
2024
21
0.240
Why?
Solubility
1
2024
69
0.240
Why?
DNA-Activated Protein Kinase
1
2024
26
0.240
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
14
0.230
Why?
Morpholines
1
2024
71
0.230
Why?
Proto-Oncogenes
1
2024
27
0.230
Why?
Phosphorylation
4
2021
535
0.230
Why?
Mice
7
2024
5739
0.230
Why?
NIH 3T3 Cells
3
2021
52
0.220
Why?
Lymphoma
1
2024
66
0.220
Why?
Patents as Topic
1
2022
8
0.220
Why?
Drug Evaluation, Preclinical
3
2021
144
0.210
Why?
Mutation
4
2022
1294
0.210
Why?
CARD Signaling Adaptor Proteins
1
2022
5
0.210
Why?
Drug Screening Assays, Antitumor
5
2021
136
0.210
Why?
Chemistry Techniques, Synthetic
3
2020
20
0.210
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
154
0.200
Why?
Clinical Trials as Topic
2
2021
461
0.200
Why?
Transfection
1
2022
354
0.200
Why?
Phthalazines
1
2021
20
0.190
Why?
Indoles
1
2024
278
0.190
Why?
Thiophenes
1
2021
36
0.190
Why?
Acetamides
1
2021
20
0.190
Why?
Quinazolines
1
2020
33
0.180
Why?
Aziridines
1
2020
2
0.180
Why?
Maleimides
1
2020
8
0.180
Why?
Cell Line
3
2021
1000
0.180
Why?
Pyrroles
1
2020
69
0.180
Why?
Protein Interaction Mapping
1
2020
40
0.180
Why?
Ketones
1
2019
9
0.170
Why?
Molecular Dynamics Simulation
1
2019
33
0.170
Why?
Phosphoproteins
1
2020
107
0.170
Why?
Oxidative Stress
1
2024
770
0.170
Why?
Adenosine Triphosphate
1
2020
233
0.170
Why?
Oligopeptides
1
2019
89
0.170
Why?
Decarboxylation
1
2018
3
0.160
Why?
Apoptosis
3
2022
1101
0.160
Why?
Receptor, trkC
1
2018
4
0.160
Why?
Metabolome
1
2019
89
0.160
Why?
Models, Chemical
1
2018
66
0.160
Why?
Isoquinolines
1
2018
25
0.160
Why?
Mice, Nude
2
2017
252
0.160
Why?
Computational Biology
1
2020
214
0.160
Why?
Bone Marrow
1
2020
362
0.160
Why?
Benzimidazoles
1
2018
48
0.150
Why?
Proto-Oncogene Proteins c-kit
1
2018
36
0.150
Why?
Heterocyclic Compounds
1
2018
28
0.150
Why?
Boronic Acids
1
2018
182
0.150
Why?
Software
1
2020
273
0.150
Why?
Ligands
2
2015
204
0.150
Why?
Nitrazepam
1
2016
1
0.140
Why?
Proteomics
1
2020
329
0.140
Why?
Glioblastoma
1
2017
92
0.130
Why?
Libraries, Digital
1
2015
2
0.130
Why?
Molecular Weight
1
2015
84
0.130
Why?
Carboxylic Acids
1
2015
17
0.130
Why?
Colorectal Neoplasms
1
2018
236
0.130
Why?
Human Umbilical Vein Endothelial Cells
1
2015
90
0.120
Why?
Palladium
1
2014
4
0.120
Why?
Brain Neoplasms
1
2017
287
0.110
Why?
Protein Interaction Domains and Motifs
1
2013
20
0.110
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
66
0.110
Why?
Molecular Targeted Therapy
1
2013
119
0.100
Why?
Drug Resistance, Neoplasm
1
2013
308
0.100
Why?
Cells, Cultured
1
2014
1573
0.090
Why?
Mice, Inbred BALB C
2
2020
304
0.080
Why?
Cell Survival
2
2021
600
0.080
Why?
Protein Binding
2
2020
660
0.080
Why?
Guanylate Cyclase
1
2022
9
0.050
Why?
DNA Damage
1
2024
301
0.050
Why?
Furans
1
2022
26
0.050
Why?
Oncogenes
1
2022
57
0.050
Why?
T-Lymphocytes
1
2024
338
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
86
0.050
Why?
Receptors, Transforming Growth Factor beta
1
2021
25
0.050
Why?
Smad Proteins
1
2021
11
0.050
Why?
Tumor Cells, Cultured
1
2022
465
0.050
Why?
Blood-Brain Barrier
1
2021
48
0.050
Why?
Wound Healing
1
2022
204
0.050
Why?
Binding, Competitive
1
2020
94
0.050
Why?
Amino Acid Motifs
1
2020
56
0.040
Why?
Hematopoiesis
1
2020
71
0.040
Why?
Workflow
1
2020
51
0.040
Why?
Xenopus laevis
1
2019
38
0.040
Why?
Binding Sites
1
2021
374
0.040
Why?
Protein Structure, Secondary
1
2019
72
0.040
Why?
Databases, Genetic
1
2020
88
0.040
Why?
Stereoisomerism
1
2019
104
0.040
Why?
Ethanol
1
2022
340
0.040
Why?
Cell Movement
1
2020
247
0.040
Why?
Mass Spectrometry
1
2020
306
0.040
Why?
Catalytic Domain
1
2018
57
0.040
Why?
Cell Cycle Checkpoints
1
2018
32
0.040
Why?
Female
4
2020
26472
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Neoplasm Transplantation
1
2017
85
0.040
Why?
Enzyme Activation
1
2018
276
0.040
Why?
Gene Silencing
1
2017
119
0.040
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
7
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2016
4
0.040
Why?
Polyploidy
1
2016
11
0.040
Why?
Protein Conformation
1
2016
166
0.030
Why?
Neoplastic Stem Cells
1
2017
103
0.030
Why?
Xenograft Model Antitumor Assays
1
2016
211
0.030
Why?
Hydrazines
1
2015
15
0.030
Why?
Solvents
1
2015
29
0.030
Why?
Metals
1
2015
34
0.030
Why?
Carbon
1
2015
54
0.030
Why?
Rats, Sprague-Dawley
1
2018
1597
0.030
Why?
Microwaves
1
2014
11
0.030
Why?
Catalysis
1
2014
88
0.030
Why?
Kinetics
1
2015
623
0.030
Why?
Cell Cycle Proteins
1
2013
166
0.030
Why?
Rats
1
2016
3305
0.020
Why?
Models, Biological
1
2013
727
0.020
Why?
Male
2
2020
25241
0.020
Why?
Frett's Networks
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