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Brendan Frett

Concepts (149)

Concept scores are derived automatically based on a person's publications. Keywords in the their attributed publications are matched to keywords from the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). The strength of a person's concept scores is based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the topic.Concepts cannot be directly edited. You can help ensure your concepts are accurate by making sure your attributed publications are correct and up-to-date. We recommend checking over your attributed publications list every three to four months.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors
18
2022
216
4.930
Why?
Proto-Oncogene Proteins c-ret
10
2024
35
4.440
Why?
Drug Discovery
10
2021
90
3.360
Why?
Antineoplastic Agents
15
2021
1300
1.930
Why?
Pyridines
6
2021
137
1.270
Why?
Neoplasms
7
2021
1322
1.170
Why?
Small Molecule Libraries
6
2021
72
1.100
Why?
Drug Design
9
2021
133
1.100
Why?
Leukemia, Myeloid, Acute
2
2024
192
1.010
Why?
Transforming Growth Factor beta
2
2022
158
0.980
Why?
Gene Rearrangement
1
2024
76
0.920
Why?
fms-Like Tyrosine Kinase 3
3
2021
16
0.890
Why?
Molecular Structure
10
2021
319
0.860
Why?
Lung Neoplasms
3
2024
643
0.850
Why?
Aminoquinolines
1
2021
11
0.820
Why?
Structure-Activity Relationship
11
2022
423
0.810
Why?
Adenine
1
2021
44
0.790
Why?
Pyrazoles
2
2021
110
0.780
Why?
Intracellular Signaling Peptides and Proteins
1
2021
151
0.760
Why?
Cell Line, Tumor
15
2024
1552
0.760
Why?
Tumor Microenvironment
1
2022
210
0.750
Why?
Imidazoles
2
2018
143
0.740
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2020
37
0.720
Why?
Receptor, trkA
3
2021
6
0.570
Why?
ras Proteins
2
2013
70
0.560
Why?
Pyrimidines
4
2022
196
0.540
Why?
Computer-Aided Design
1
2015
21
0.520
Why?
Dose-Response Relationship, Drug
6
2021
1477
0.490
Why?
Cyclic Nucleotide Phosphodiesterases, Type 6
1
2013
1
0.470
Why?
Proto-Oncogene Proteins
2
2013
169
0.460
Why?
Humans
30
2024
54397
0.420
Why?
Lymphoma, Large B-Cell, Diffuse
2
2024
106
0.420
Why?
HEK293 Cells
4
2021
245
0.410
Why?
Models, Molecular
4
2020
423
0.380
Why?
Cell Proliferation
8
2022
1097
0.380
Why?
Receptor, trkB
2
2021
11
0.370
Why?
Molecular Conformation
3
2019
73
0.330
Why?
Animals
12
2024
14411
0.310
Why?
Signal Transduction
5
2022
1754
0.280
Why?
Molecular Docking Simulation
3
2021
83
0.260
Why?
Myeloid-Lymphoid Leukemia Protein
1
2024
16
0.240
Why?
Proto-Oncogenes
1
2024
29
0.240
Why?
Phosphorylation
4
2021
613
0.240
Why?
NIH 3T3 Cells
3
2021
55
0.230
Why?
Lymphoma
1
2024
72
0.230
Why?
Mice
7
2024
6429
0.230
Why?
Patents as Topic
1
2022
7
0.220
Why?
Drug Evaluation, Preclinical
3
2021
158
0.220
Why?
CARD Signaling Adaptor Proteins
1
2022
5
0.220
Why?
Chemistry Techniques, Synthetic
3
2020
20
0.220
Why?
Drug Screening Assays, Antitumor
5
2021
142
0.220
Why?
Carcinoma, Non-Small-Cell Lung
1
2024
164
0.210
Why?
Mutation
4
2022
1504
0.210
Why?
Transfection
1
2022
399
0.210
Why?
Clinical Trials as Topic
2
2021
491
0.200
Why?
Phthalazines
1
2021
19
0.200
Why?
Thiophenes
1
2021
37
0.200
Why?
Acetamides
1
2021
25
0.190
Why?
Quinazolines
1
2020
39
0.190
Why?
Aziridines
1
2020
2
0.190
Why?
Maleimides
1
2020
9
0.190
Why?
Pyrroles
1
2020
78
0.180
Why?
Protein Interaction Mapping
1
2020
44
0.180
Why?
Ketones
1
2019
9
0.180
Why?
Cell Line
3
2021
1152
0.180
Why?
Molecular Dynamics Simulation
1
2019
40
0.180
Why?
Phosphoproteins
1
2020
116
0.180
Why?
Adenosine Triphosphate
1
2020
242
0.170
Why?
Oligopeptides
1
2019
95
0.170
Why?
Decarboxylation
1
2018
3
0.170
Why?
Receptor, trkC
1
2018
4
0.170
Why?
Models, Chemical
1
2018
65
0.170
Why?
Isoquinolines
1
2018
25
0.160
Why?
Metabolome
1
2019
109
0.160
Why?
Mice, Nude
2
2017
284
0.160
Why?
Apoptosis
3
2022
1302
0.160
Why?
Oxidative Stress
1
2024
958
0.160
Why?
Computational Biology
1
2020
231
0.160
Why?
Bone Marrow
1
2020
414
0.160
Why?
Proto-Oncogene Proteins c-kit
1
2018
35
0.160
Why?
Benzimidazoles
1
2018
54
0.160
Why?
Heterocyclic Compounds
1
2018
30
0.160
Why?
Boronic Acids
1
2018
197
0.160
Why?
Software
1
2020
297
0.150
Why?
Ligands
2
2015
229
0.150
Why?
Nitrazepam
1
2016
1
0.150
Why?
Proteomics
1
2020
343
0.150
Why?
Glioblastoma
1
2017
99
0.140
Why?
Libraries, Digital
1
2015
2
0.130
Why?
Carboxylic Acids
1
2015
17
0.130
Why?
Molecular Weight
1
2015
100
0.130
Why?
Colorectal Neoplasms
1
2018
237
0.130
Why?
Human Umbilical Vein Endothelial Cells
1
2015
95
0.130
Why?
Palladium
1
2014
5
0.120
Why?
Protein Interaction Domains and Motifs
1
2013
26
0.120
Why?
Brain Neoplasms
1
2017
285
0.120
Why?
Proto-Oncogene Proteins p21(ras)
1
2013
70
0.120
Why?
Molecular Targeted Therapy
1
2013
128
0.110
Why?
Drug Resistance, Neoplasm
1
2013
309
0.100
Why?
Cells, Cultured
1
2014
1737
0.090
Why?
Mice, Inbred BALB C
2
2020
370
0.080
Why?
Cell Survival
2
2021
657
0.080
Why?
Protein Binding
2
2020
736
0.080
Why?
Guanylate Cyclase
1
2022
10
0.050
Why?
Furans
1
2022
27
0.050
Why?
Oncogenes
1
2022
63
0.050
Why?
Apoptosis Regulatory Proteins
1
2022
96
0.050
Why?
Smad Proteins
1
2021
13
0.050
Why?
Receptors, Transforming Growth Factor beta
1
2021
26
0.050
Why?
Tumor Cells, Cultured
1
2022
477
0.050
Why?
Blood-Brain Barrier
1
2021
59
0.050
Why?
Binding, Competitive
1
2020
113
0.050
Why?
Amino Acid Motifs
1
2020
57
0.050
Why?
Workflow
1
2020
57
0.050
Why?
Wound Healing
1
2022
228
0.050
Why?
Hematopoiesis
1
2020
80
0.050
Why?
Xenopus laevis
1
2019
49
0.050
Why?
Protein Structure, Secondary
1
2019
99
0.040
Why?
Binding Sites
1
2021
440
0.040
Why?
Databases, Genetic
1
2020
101
0.040
Why?
Ethanol
1
2022
323
0.040
Why?
Stereoisomerism
1
2019
106
0.040
Why?
Cell Movement
1
2020
271
0.040
Why?
Mass Spectrometry
1
2020
313
0.040
Why?
Catalytic Domain
1
2018
61
0.040
Why?
Cell Cycle Checkpoints
1
2018
35
0.040
Why?
Aza Compounds
1
2018
14
0.040
Why?
Female
4
2020
28474
0.040
Why?
Neoplasm Transplantation
1
2017
94
0.040
Why?
Enzyme Activation
1
2018
328
0.040
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
7
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2016
4
0.040
Why?
Gene Silencing
1
2017
129
0.040
Why?
Polyploidy
1
2016
11
0.040
Why?
Neoplastic Stem Cells
1
2017
104
0.040
Why?
Xenograft Model Antitumor Assays
1
2016
220
0.040
Why?
Protein Conformation
1
2016
226
0.040
Why?
Hydrazines
1
2015
16
0.030
Why?
Solvents
1
2015
35
0.030
Why?
Metals
1
2015
44
0.030
Why?
Carbon
1
2015
61
0.030
Why?
Microwaves
1
2014
12
0.030
Why?
Rats, Sprague-Dawley
1
2018
1664
0.030
Why?
Catalysis
1
2014
98
0.030
Why?
Kinetics
1
2015
692
0.030
Why?
Cell Cycle Proteins
1
2013
198
0.030
Why?
Rats
1
2016
3419
0.020
Why?
Models, Biological
1
2013
825
0.020
Why?
Male
2
2020
27348
0.020
Why?
Frett's Networks
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