Calcium
"Calcium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Descriptor ID |
D002118
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MeSH Number(s) |
D01.268.552.100 D01.552.539.288 D23.119.100
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Concept/Terms |
Calcium- Calcium
- Coagulation Factor IV
- Factor IV, Coagulation
- Factor IV
- Blood Coagulation Factor IV
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Below are MeSH descriptors whose meaning is more general than "Calcium".
Below are MeSH descriptors whose meaning is more specific than "Calcium".
This graph shows the total number of publications written about "Calcium" by people in UAMS Profiles by year, and whether "Calcium" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 2 | 0 | 2 | 2023 | 0 | 3 | 3 | 2022 | 3 | 4 | 7 | 2021 | 4 | 2 | 6 | 2020 | 4 | 2 | 6 | 2019 | 1 | 3 | 4 | 2018 | 2 | 4 | 6 | 2017 | 2 | 2 | 4 | 2016 | 3 | 3 | 6 | 2015 | 4 | 6 | 10 | 2014 | 7 | 7 | 14 | 2013 | 4 | 9 | 13 | 2012 | 0 | 8 | 8 | 2011 | 0 | 8 | 8 | 2010 | 3 | 5 | 8 | 2009 | 8 | 7 | 15 | 2008 | 4 | 5 | 9 | 2007 | 4 | 4 | 8 | 2006 | 4 | 5 | 9 | 2005 | 4 | 9 | 13 | 2004 | 7 | 7 | 14 | 2003 | 5 | 7 | 12 | 2002 | 5 | 14 | 19 | 2001 | 1 | 4 | 5 | 2000 | 3 | 2 | 5 | 1999 | 2 | 5 | 7 | 1998 | 3 | 6 | 9 | 1997 | 1 | 1 | 2 | 1996 | 3 | 1 | 4 | 1995 | 4 | 0 | 4 | 1994 | 6 | 2 | 8 | 1993 | 2 | 3 | 5 | 1992 | 0 | 4 | 4 | 1991 | 2 | 3 | 5 | 1990 | 4 | 2 | 6 | 1989 | 3 | 4 | 7 |
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Below are the most recent publications written about "Calcium" by people in Profiles over the past ten years.
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Pal S, Bagchi AK, Stolarz AJ. Real-Time Evaluation of Absolute, Cytosolic, Free Ca2+ and Corresponding Contractility in Isolated, Pressurized Lymph Vessels. J Vis Exp. 2024 Mar 22; (205).
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Athavale ON, Avci R, Clark AR, Di Natale MR, Wang X, Furness JB, Liu Z, Cheng LK, Du P. Neural regulation of slow waves and phasic contractions in the distal stomach: a mathematical model. J Neural Eng. 2024 01 04; 20(6).
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Gruslova AB, Katta N, Nolen D, Jenney S, Vela D, Buja M, Cilingiroglu M, Seddighi Y, Han HC, Milner TE, Feldman MD. Intravascular laser lithotripsy for calcium fracture in human coronary arteries. EuroIntervention. 2023 Dec 18; 19(11):e913-e922.
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Gruslova AB, Inanc IH, Cilingiroglu M, Katta N, Milner TE, Feldman MD. Review of intravascular lithotripsy for treating coronary, peripheral artery, and valve calcifications. Catheter Cardiovasc Interv. 2024 02; 103(2):295-307.
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McWhorter CA, Mead MJ, Rodgers MD, Ebeling MD, Shary JR, Gregoski MJ, Newton DA, Baatz JE, Hollis BW, Hewison M, Wagner CL. Predicting comorbidities of pregnancy: A comparison between total and free 25(OH)D and their associations with parathyroid hormone. J Steroid Biochem Mol Biol. 2023 12; 235:106420.
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Hodges JK, Maiz M, Cao S, Lachcik PJ, Peacock M, McCabe GP, McCabe LD, Cladis DP, Jackson GS, Ferruzzi MG, Lila MA, Bailey RL, Martin BR, Weaver CM. Moderate consumption of freeze-dried blueberry powder increased net bone calcium retention compared with no treatment in healthy postmenopausal women: a randomized crossover trial. Am J Clin Nutr. 2023 08; 118(2):382-390.
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Williams JN, Irwin M, Li Y, Kambrath AV, Mattingly BT, Patel S, Kittaka M, Collins RN, Clough NA, Doud EH, Mosley AL, Bellido T, Bruzzaniti A, Plotkin LI, Trinidad JC, Thompson WR, Bonewald LF, Sankar U. Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin. Int J Mol Sci. 2023 Mar 01; 24(5).
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Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes. Resuscitation. 2023 04; 185:109673.
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Jensen JC, Miedema MD. Coronary artery calcium to guide treatment in primary prevention-can we afford not to? Eur J Prev Cardiol. 2022 10 18; 29(13):1800-1801.
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Henning P, Conaway HH, Lerner UH. Stimulation of osteoclast formation and bone resorption by glucocorticoids: Synergistic interactions with the calcium regulating hormones parathyroid hormone and 1,25(OH)2-vitamin D3. Vitam Horm. 2022; 120:231-270.
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Stenhouse C, Halloran KM, Tanner AR, Suva LJ, Rozance PJ, Anthony RV, Bazer FW. Uptake of Phosphate, Calcium, and Vitamin D by the Pregnant Uterus of Sheep in Late Gestation: Regulation by Chorionic Somatomammotropin Hormone. Int J Mol Sci. 2022 Jul 14; 23(14).
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Stenhouse C, Halloran KM, Hoskins EC, Newton MG, Moses RM, Seo H, Dunlap KA, Satterfield MC, Gaddy D, Johnson GA, Wu G, Suva LJ, Bazer FW. Effects of exogenous progesterone on the expression of mineral regulatory molecules by ovine endometrium and placentomes?. Biol Reprod. 2022 06 13; 106(6):1126-1142.
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Stenhouse C, Halloran KM, Moses RM, Seo H, Gaddy D, Johnson GA, Wu G, Suva LJ, Bazer FW. Effects of progesterone and interferon tau on ovine endometrial phosphate, calcium, and vitamin D signaling?. Biol Reprod. 2022 05 17; 106(5):888-899.
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Stenhouse C, Suva LJ, Gaddy D, Wu G, Bazer FW. Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals. Adv Exp Med Biol. 2022; 1354:77-107.
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Greer ML, Davis K, Stack BC. Machine learning can identify patients at risk of hyperparathyroidism without known calcium and intact parathyroid hormone. Head Neck. 2022 04; 44(4):817-822.
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Desai VG, Vijay V, Han T, Moland CL, Phanavanh B, Lee T, Davis KJ, Muskhelishvili L, Stine KC, Fuscoe JC. Doxorubicin-induced delayed-onset subclinical cardiotoxicity in mice. J Appl Toxicol. 2022 05; 42(5):778-792.
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Chen X, Qin Y, Zhang Y, Yang X, Xing Z, Shen Y, Cheng J, Yeh ETH, Wu H, Qi Y. SENP2-PLC?4 signaling regulates neurogenesis through the maintenance of calcium homeostasis. Cell Death Differ. 2022 02; 29(2):337-350.
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Stenhouse C, Halloran KM, Newton MG, Gaddy D, Suva LJ, Bazer FW. Novel mineral regulatory pathways in ovine pregnancy: II. Calcium-binding proteins, calcium transporters, and vitamin D signaling. Biol Reprod. 2021 07 02; 105(1):232-243.
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Mhanna M, Beran A, Nazir S, Sajdeya O, Srour O, Elzanaty A, Eltahawy EA. Efficacy and Safety of Intravascular Lithotripsy in Calcified Coronary Lesions: A Systematic Review and Meta-Analysis. Cardiovasc Revasc Med. 2022 03; 36:73-82.
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Pham AK, Miller M, Rosenthal P, Das S, Weng N, Jang S, Kurten RC, Badrani J, Doherty TA, Oliver B, Broide DH. ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility. JCI Insight. 2021 04 08; 6(7).
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Kavouras SA, Suh HG, Vallet M, Daudon M, Mauromoustakos A, Vecchio M, Tack I. Urine osmolality predicts calcium-oxalate crystallization risk in patients with recurrent urolithiasis. Urolithiasis. 2021 Oct; 49(5):399-405.
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Hollowoa BR, Spencer HJ, Stack BC. Normocalcemic and Normohormonal Primary Hyperparathyroidism: Laboratory Values and End-Organ Effects. Otolaryngol Head Neck Surg. 2021 09; 165(3):387-397.
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Klemens CA, Chulkov EG, Wu J, Hye Khan MA, Levchenko V, Flister MJ, Imig JD, Kriegel AJ, Palygin O, Staruschenko A. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores. Hypertension. 2021 02; 77(2):582-593.
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Xiang B, Zhang G, Zhang Y, Wu C, Joshi S, Morris AJ, Ware J, Smyth SS, Whiteheart SW, Li Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):234-249.
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Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA, Dong X, An SS. The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28485-28495.
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Wright C, King D, Small M, Gibson C, Gardner R, Stack BC. The Utility of the Cl:PO4 Ratio in Patients With Variant Versions of Primary Hyperparathyroidism. Otolaryngol Head Neck Surg. 2021 02; 164(2):308-314.
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Cladis DP, Debelo H, Lachcik PJ, Ferruzzi MG, Weaver CM. Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats. Mol Nutr Food Res. 2020 06; 64(12):e2000031.
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Harding EK, Boivin B, Salter MW. Intracellular Calcium Responses Encode Action Potential Firing in Spinal Cord Lamina I Neurons. J Neurosci. 2020 06 03; 40(23):4439-4456.
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Bauer JM, Miku?ov? L, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, Mets T, Wijers SLJ, Garthoff JA, Luiking Y, Sieber C, Cederholm T. Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adults. Aging Clin Exp Res. 2020 Aug; 32(8):1501-1514.
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Lau LH, Cliff ERS, Wong V, Wong H, Torkamani N, Eer A, Weickhardt A, Grossmann M. Hypocalcaemia following denosumab in prostate cancer: A clinical review. Clin Endocrinol (Oxf). 2020 06; 92(6):495-502.
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Suva LJ, Friedman PA. PTH and PTHrP Actions on Bone. Handb Exp Pharmacol. 2020; 262:27-45.
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Urbano FJ, Bisagno V, Garcia-Rill E. Gamma oscillations in the pedunculopontine nucleus are regulated by F-actin: neuroepigenetic implications. Am J Physiol Cell Physiol. 2020 02 01; 318(2):C282-C288.
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Vicogne D, Houdou M, Garat A, Climer L, Lupashin V, Morelle W, Foulquier F. Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells. J Inherit Metab Dis. 2020 03; 43(2):357-366.
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Caldwell M, Laux J, Clark M, Kim L, Rubin J. Persistently Elevated PTH After Parathyroidectomy at One Year: Experience in a Tertiary Referral Center. J Clin Endocrinol Metab. 2019 10 01; 104(10):4473-4480.
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Lebredonchel E, Houdou M, Potelle S, de Bettignies G, Schulz C, Krzewinski Recchi MA, Lupashin V, Legrand D, Klein A, Foulquier F. Dissection of TMEM165 function in Golgi glycosylation and its Mn2+ sensitivity. Biochimie. 2019 Oct; 165:123-130.
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Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Barrington BC, Asfaw YG, Moseley MA, Steinbach WJ. Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus. Mol Microbiol. 2019 07; 112(1):62-80.
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Varghese RT, Khasawneh K, Desikan RK, Subramaniam A, Weaver T, Nair GKV. Vitamin A and Hydrochlorothiazide Causing Severe Hypercalcemia in a Patient With Primary Hyperparathyroidism. J Investig Med High Impact Case Rep. 2019 Jan-Dec; 7:2324709618823805.
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Shah RJ, Lieske JC. Inching toward a Greater Understanding of Genetic Hypercalciuria: The Role of Claudins. Clin J Am Soc Nephrol. 2018 10 08; 13(10):1460-1462.
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Caviness P, Bauer R, Tanaka K, Janowska K, Roeser JR, Harter D, Sanders J, Ruth C, Matsushita O, Sakon J. Ca2+ -induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation. FEBS J. 2018 09; 285(17):3254-3269.
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Stack BC, Tolley NS, Bartel TB, Bilezikian JP, Bodenner D, Camacho P, Cox JPDT, Dralle H, Jackson JE, Morris JC, Orloff LA, Palazzo F, Ridge JA, Scott-Coombes D, Steward DL, Terris DJ, Thompson G, Randolph GW. AHNS Series: Do you know your guidelines? Optimizing outcomes in reoperative parathyroid surgery: Definitive multidisciplinary joint consensus guidelines of the American Head and Neck Society and the British Association of Endocrine and Thyroid Surgeons. Head Neck. 2018 08; 40(8):1617-1629.
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O'Brien CA, Morello R. Modeling Rare Bone Diseases in Animals. Curr Osteoporos Rep. 2018 08; 16(4):458-465.
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Zangari M, Yoo H, Shin I, Kim B, Edmondson R, Morgan GJ, Suva LJ, Yoon D. Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice. Endocrinology. 2018 04 01; 159(4):1561-1569.
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Gokulan K, Khare S, Cerniglia CE, Foley SL, Varughese KI. Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation. AAPS J. 2018 03 09; 20(2):44.
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Hill BJF, Dalton RJ, Joseph BK, Thakali KM, Rusch NJ. 17?-estradiol reduces Cav 1.2 channel abundance and attenuates Ca2+ -dependent contractions in coronary arteries. Pharmacol Res Perspect. 2017 10; 5(5).
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Jain N, Reilly RF. Hungry bone syndrome. Curr Opin Nephrol Hypertens. 2017 07; 26(4):250-255.
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Lowery CL, Elliott C, Cooper A, Hadden C, Sonon RN, Azadi P, Williams DK, Marsh JD, Woulfe DS, Kilic F. Cigarette Smoking-Associated Alterations in Serotonin/Adrenalin Signaling Pathways of Platelets. J Am Heart Assoc. 2017 May 18; 6(5).
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Shamsuzzaman S, Onal M, St John HC, Jeffery JJ, Pike JW. Absence of the Vitamin D Receptor Inhibits Atherosclerotic Plaque Calcification in Female Hypercholesterolemic Mice. J Cell Biochem. 2017 05; 118(5):1050-1064.
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Juvvadi PR. Balancing iron and calcium: Flavin carrier family proteins in Aspergillus fumigatus virulence. Virulence. 2017 08 18; 8(6):621-624.
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Nguy L, Shubbar E, Jern?s M, Nookaew I, Lundgren J, Olsson B, Nilsson H, Guron G. Adenine-induced chronic renal failure in rats decreases aortic relaxation rate and alters expression of proteins involved in vascular smooth muscle calcium handling. Acta Physiol (Oxf). 2016 12; 218(4):250-264.
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Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW, Geurts AM, Staruschenko A, Imig JD, Sorokin A. p66Shc regulates renal vascular tone in hypertension-induced nephropathy. J Clin Invest. 2016 07 01; 126(7):2533-46.
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Tripathi R, Singh P, Singh A, Chagtoo M, Khan S, Tiwari S, Agarwal G, Meeran SM, Godbole MM. Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress. Nutr Cancer. 2016 May-Jun; 68(4):679-88.
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Pryde KR, Smith HL, Chau KY, Schapira AH. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016 04 25; 213(2):163-71.
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Yeruva L, Spencer NE, Saraf MK, Hennings L, Bowlin AK, Cleves MA, Mercer K, Chintapalli SV, Shankar K, Rank RG, Badger TM, Ronis MJ. Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model. BMC Gastroenterol. 2016 Mar 22; 16:40.
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Nelson KL, Hinson AM, Lawson BR, Middleton D, Bodenner DL, Stack BC. Postoperative Calcium Management in Same-Day Discharge Thyroid and Parathyroid Surgery. Otolaryngol Head Neck Surg. 2016 05; 154(5):854-60.
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Hinson AM, Wilkerson BM, Rothman-Fitts I, Riggs AT, Stack BC, Bodenner DL. Hyperparathyroidism Associated with Long-Term Proton Pump Inhibitors Independent of Concurrent Bisphosphonate Therapy in Elderly Adults. J Am Geriatr Soc. 2015 Oct; 63(10):2070-3.
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Wang X, Ding Z, Lin J, Guo Z, Mehta JL. LOX-1 in macrophage migration in response to ox-LDL and the involvement of calpains. Biochem Biophys Res Commun. 2015 Nov 06; 467(1):135-9.
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Stimers JR, Song L, Rusch NJ, Rhee SW. Overexpression of the Large-Conductance, Ca2+-Activated K+ (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes. PLoS One. 2015; 10(6):e0130588.
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Slikker W, Liu F, Rainosek SW, Patterson TA, Sadovova N, Hanig JP, Paule MG, Wang C. Ketamine-Induced Toxicity in Neurons Differentiated from Neural Stem Cells. Mol Neurobiol. 2015 Oct; 52(2):959-69.
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Juvvadi PR, Mu?oz A, Lamoth F, Soderblom EJ, Moseley MA, Read ND, Steinbach WJ. Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus. Antimicrob Agents Chemother. 2015 Aug; 59(8):4946-55.
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Kim D, Kim I, Wang J, White C, Carroll JL. Hydrogen sulfide and hypoxia-induced changes in TASK (K2P3/9) activity and intracellular Ca(2+) concentration in rat carotid body glomus cells. Respir Physiol Neurobiol. 2015 Aug 15; 215:30-8.
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Goossens KV, Ielasi FS, Nookaew I, Stals I, Alonso-Sarduy L, Daenen L, Van Mulders SE, Stassen C, van Eijsden RG, Siewers V, Delvaux FR, Kasas S, Nielsen J, Devreese B, Willaert RG. Molecular mechanism of flocculation self-recognition in yeast and its role in mating and survival. mBio. 2015 Apr 14; 6(2).
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McCoin CS, Knotts TA, Ono-Moore KD, Oort PJ, Adams SH. Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and -independent effects. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E990-E1000.
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ter Borg S, Verlaan S, Hemsworth J, Mijnarends DM, Schols JM, Luiking YC, de Groot LC. Micronutrient intakes and potential inadequacies of community-dwelling older adults: a systematic review. Br J Nutr. 2015 Apr 28; 113(8):1195-206.
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Uretsky S, Chokshi N, Kobrinski T, Agarwal SK, Po JR, Awan H, Jagarlamudi A, Gudiwada SP, D'Avino RC, Rozanski A. The interplay of physician awareness and reporting of incidentally found coronary artery calcium on the clinical management of patients who underwent noncontrast chest computed tomography. Am J Cardiol. 2015 Jun 01; 115(11):1513-7.
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Hedgepeth SC, Garcia MI, Wagner LE, Rodriguez AM, Chintapalli SV, Snyder RR, Hankins GD, Henderson BR, Brodie KM, Yule DI, van Rossum DB, Boehning D. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. J Biol Chem. 2015 Mar 13; 290(11):7304-13.
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Kim I, Fite L, Donnelly DF, Kim JH, Carroll JL. Possible Role of TRP Channels in Rat Glomus Cells. Adv Exp Med Biol. 2015; 860:227-32.
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