 Aspergillus fumigatus
"Aspergillus fumigatus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of imperfect fungi from which the antibiotic fumigatin is obtained. Its spores may cause respiratory infection in birds and mammals.
| Descriptor ID |
D001232
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| MeSH Number(s) |
B01.300.381.081.295
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aspergillus fumigatus".
Below are MeSH descriptors whose meaning is more specific than "Aspergillus fumigatus".
This graph shows the total number of publications written about "Aspergillus fumigatus" by people in UAMS Profiles by year, and whether "Aspergillus fumigatus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2020 | 5 | 1 | 6 | | 2019 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2017 | 6 | 0 | 6 | | 2016 | 4 | 0 | 4 | | 2015 | 4 | 0 | 4 | | 2014 | 4 | 0 | 4 | | 2013 | 5 | 0 | 5 | | 2012 | 3 | 0 | 3 | | 2011 | 5 | 0 | 5 | | 2010 | 4 | 0 | 4 | | 2009 | 1 | 0 | 1 | | 2008 | 4 | 0 | 4 | | 2007 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2004 | 3 | 0 | 3 | | 2003 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aspergillus fumigatus" by people in Profiles over the past ten years.
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Shaheen SK, Juvvadi PR, Allen J, Shwab EK, Cole DC, Asfaw YG, Kapoor M, Shaw KJ, Steinbach WJ. In Vitro Activity of APX2041, a New Gwt1 Inhibitor, and In Vivo Efficacy of the Prodrug APX2104 against Aspergillus fumigatus. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0068221.
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Shwab EK, Juvvadi PR, Waitt G, Shaheen S, Allen J, Soderblom EJ, Bobay BG, Asfaw YG, Moseley MA, Steinbach WJ. The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets. mBio. 2020 12 15; 11(6).
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Roundtree MT, Juvvadi PR, Shwab EK, Cole DC, Steinbach WJ. Aspergillus fumigatus Cyp51A and Cyp51B Proteins Are Compensatory in Function and Localize Differentially in Response to Antifungals and Cell Wall Inhibitors. Antimicrob Agents Chemother. 2020 09 21; 64(10).
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Assress HA, Selvarajan R, Nyoni H, Ogola HJO, Mamba BB, Msagati TAM. Azole antifungal resistance in fungal isolates from wastewater treatment plant effluents. Environ Sci Pollut Res Int. 2021 Jan; 28(3):3217-3229.
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Xu-Vanpala S, Deerhake ME, Wheaton JD, Parker ME, Juvvadi PR, MacIver N, Ciofani M, Shinohara ML. Functional heterogeneity of alveolar macrophage population based on expression of CXCL2. Sci Immunol. 2020 08 07; 5(50).
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Renshaw H, Juvvadi PR, Cole DC, Steinbach WJ. The class V myosin interactome of the human pathogen Aspergillus fumigatus reveals novel interactions with COPII vesicle transport proteins. Biochem Biophys Res Commun. 2020 06 18; 527(1):232-237.
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Juvvadi PR, Bobay BG, Gobeil SMC, Cole DC, Venters RA, Heitman J, Spicer LD, Steinbach WJ. FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus. Biochem Biophys Res Commun. 2020 05 21; 526(1):48-54.
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Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher MA, Heitman J, Steinbach WJ. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun. 2019 09 19; 10(1):4275.
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Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Barrington BC, Asfaw YG, Moseley MA, Steinbach WJ. Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus. Mol Microbiol. 2019 07; 112(1):62-80.
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Juvvadi PR, Cole DC, Falloon K, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus. Biochem Biophys Res Commun. 2018 11 02; 505(3):740-746.
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Renshaw H, Vargas-Mu?iz JM, Juvvadi PR, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth. J Cell Sci. 2018 02 07; 131(3).
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Juvvadi PR, Moseley MA, Hughes CJ, Soderblom EJ, Lennon S, Perkins SR, Thompson JW, Geromanos SJ, Wildgoose J, Richardson K, Langridge JI, Vissers JPC, Steinbach WJ. Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs. J Proteome Res. 2018 02 02; 17(2):780-793.
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Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Steinbach WJ. Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms. FEBS Lett. 2017 11; 591(22):3730-3744.
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Moreno-Vel?squez SD, Seidel C, Juvvadi PR, Steinbach WJ, Read ND. Caspofungin-Mediated Growth Inhibition and Paradoxical Growth in Aspergillus fumigatus Involve Fungicidal Hyphal Tip Lysis Coupled with Regenerative Intrahyphal Growth and Dynamic Changes in ?-1,3-Glucan Synthase Localization. Antimicrob Agents Chemother. 2017 10; 61(10).
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Wong SSW, Rasid O, Laskaris P, Fekkar A, Cavaillon JM, Steinbach WJ, Ibrahim-Granet O. Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population. Virulence. 2017 11 17; 8(8):1744-1752.
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Vargas-Mu?iz JM, Renshaw H, Waitt G, Soderblom EJ, Moseley MA, Palmer JM, Juvvadi PR, Keller NP, Steinbach WJ. Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus. Biochem Biophys Res Commun. 2017 04 01; 485(2):221-226.
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Shwab EK, Juvvadi PR, Waitt G, Soderblom EJ, Moseley MA, Nicely NI, Asfaw YG, Steinbach WJ. A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus. mBio. 2017 02 07; 8(1).
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Juvvadi PR. Balancing iron and calcium: Flavin carrier family proteins in Aspergillus fumigatus virulence. Virulence. 2017 08 18; 8(6):621-624.
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Tonthat NK, Juvvadi PR, Zhang H, Lee SC, Venters R, Spicer L, Steinbach WJ, Heitman J, Schumacher MA. Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. mBio. 2016 Apr 26; 7(2):e00492-16.
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Renshaw H, Vargas-Mu?iz JM, Richards AD, Asfaw YG, Juvvadi PR, Steinbach WJ. Distinct Roles of Myosins in Aspergillus fumigatus Hyphal Growth and Pathogenesis. Infect Immun. 2016 05; 84(5):1556-64.
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Juvvadi PR, Pemble CW, Ma Y, Steinbach WJ. Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus. FEBS Lett. 2016 Feb; 590(4):501-8.
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Falloon K, Juvvadi PR, Richards AD, Vargas-Mu?iz JM, Renshaw H, Steinbach WJ. Characterization of the FKBP12-Encoding Genes in Aspergillus fumigatus. PLoS One. 2015; 10(9):e0137869.
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Juvvadi PR, Mu?oz A, Lamoth F, Soderblom EJ, Moseley MA, Read ND, Steinbach WJ. Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus. Antimicrob Agents Chemother. 2015 Aug; 59(8):4946-55.
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Vargas-Mu?iz JM, Renshaw H, Richards AD, Lamoth F, Soderblom EJ, Moseley MA, Juvvadi PR, Steinbach WJ. The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence. Fungal Genet Biol. 2015 Aug; 81:41-51.
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Lamoth F, Juvvadi PR, Soderblom EJ, Moseley MA, Steinbach WJ. Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2015 Aug; 59(8):4727-33.
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