 Oocytes
"Oocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
| Descriptor ID |
D009865
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| MeSH Number(s) |
A05.360.490.690.680 A11.497.497.600
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| Concept/Terms |
Oocytes- Oocytes
- Oocyte
- Ovocytes
- Ovocyte
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Below are MeSH descriptors whose meaning is more general than "Oocytes".
Below are MeSH descriptors whose meaning is more specific than "Oocytes".
This graph shows the total number of publications written about "Oocytes" by people in UAMS Profiles by year, and whether "Oocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 2 | 1 | 3 | | 2024 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2022 | 3 | 2 | 5 | | 2021 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 | | 2017 | 2 | 0 | 2 | | 2016 | 1 | 1 | 2 | | 2015 | 2 | 2 | 4 | | 2014 | 1 | 2 | 3 | | 2013 | 1 | 1 | 2 | | 2012 | 2 | 1 | 3 | | 2010 | 1 | 0 | 1 | | 2009 | 3 | 1 | 4 | | 2008 | 1 | 2 | 3 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1992 | 1 | 1 | 2 | | 1990 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Oocytes" by people in Profiles over the past ten years.
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Yuen WS, Zhang QH, Dunstan M, Adhikari D, O'Connor AE, Dunleavy JEM, O'Bryan MK, Carroll J. Fertility is compromised after oocyte-specific deletion of microtubule severing protein Katanin A1. Mol Hum Reprod. 2025 Jul 03; 31(3).
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Bronson K, Banik J, Lim J, Reddick MM, Hardy L, Childs GV, MacNicol MC, MacNicol AM. Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B. Sci Rep. 2025 Apr 10; 15(1):12363.
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Bourdais A, Viard P, Bormann J, Sesbo?? C, Guerrier D, Therville N, Guillermet-Guibert J, Carroll J, Halet G. Distinct requirements for PI3K isoforms p110a and p110d for PIP3 synthesis in mouse oocytes and early embryos. Development. 2025 Mar 15; 152(6).
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Lee IW, Tazehkand AP, Sha ZY, Adhikari D, Carroll J. An aggregated mitochondrial distribution in preimplantation embryos disrupts nuclear morphology, function, and developmental potential. Proc Natl Acad Sci U S A. 2024 Jul 02; 121(27):e2317316121.
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Cai X, Stringer JM, Zerafa N, Carroll J, Hutt KJ. Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes. Cell Death Dis. 2023 07 05; 14(7):397.
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Yuen WS, Zhang QH, Bourdais A, Adhikari D, Halet G, Carroll J. Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes. Open Biol. 2023 03; 13(3):220326.
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Jarred EG, Qu Z, Tsai T, Oberin R, Petautschnig S, Bildsoe H, Pederson S, Zhang QH, Stringer JM, Carroll J, Gardner DK, Van den Buuse M, Sims NA, Gibson WT, Adelson DL, Western PS. Transient Polycomb activity represses developmental genes in growing oocytes. Clin Epigenetics. 2022 12 21; 14(1):183.
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Zhou CJ, Wang XY, Dong YH, Wang DH, Han Z, Zhang XJ, Sun QY, Carroll J, Liang CG. CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I. Nat Commun. 2022 12 13; 13(1):7732.
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Umehara T, Winstanley YE, Andreas E, Morimoto A, Williams EJ, Smith KM, Carroll J, Febbraio MA, Shimada M, Russell DL, Robker RL. Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary. Sci Adv. 2022 06 17; 8(24):eabn4564.
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Adhikari D, Lee IW, Al-Zubaidi U, Liu J, Zhang QH, Yuen WS, He L, Winstanley Y, Sesaki H, Mann JR, Robker RL, Carroll J. Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development. Sci Adv. 2022 06 17; 8(24):eabl8070.
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Adhikari D, Lee IW, Yuen WS, Carroll J. Oocyte mitochondria-key regulators of oocyte function and potential therapeutic targets for improving fertility. Biol Reprod. 2022 02 22; 106(2):366-377.
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Hutt KJ, Lim SL, Zhang QH, Gonzalez M, O'Connor AE, Merriner DJ, Liew SH, Al-Zubaidi U, Yuen WS, Adhikari D, Robker RL, Mann JR, Carroll J, O'Bryan MK. HENMT1 is involved in the maintenance of normal female fertility in the mouse. Mol Hum Reprod. 2021 11 02; 27(11).
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Al-Zubaidi U, Adhikari D, Cinar O, Zhang QH, Yuen WS, Murphy MP, Rombauts L, Robker RL, Carroll J. Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes. Hum Reprod. 2021 02 18; 36(3):771-784.
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Takei N, Takada Y, Kawamura S, Sato K, Saitoh A, Bormann J, Yuen WS, Carroll J, Kotani T. Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs. J Cell Sci. 2020 12 11; 133(23).
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Sewda A, Agopian AJ, Goldmuntz E, Hakonarson H, Morrow BE, Musfee F, Taylor D, Mitchell LE. Gene-based analyses of the maternal genome implicate maternal effect genes as risk factors for conotruncal heart defects. PLoS One. 2020; 15(6):e0234357.
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Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem. 2019 07 12; 294(28):10969-10986.
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Pisupati A, Mickolajczyk KJ, Horton W, van Rossum DB, Anishkin A, Chintapalli SV, Li X, Chu-Luo J, Busey G, Hancock WO, Jegla T. The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry. J Gen Physiol. 2018 12 03; 150(12):1702-1721.
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Chen F, Fu Q, Pu L, Zhang P, Huang Y, Hou Z, Xu Z, Chen D, Huang F, Deng T, Liang X, Lu Y, Zhang M. Integrated Analysis of Quantitative Proteome and Transcriptional Profiles Reveals the Dynamic Function of Maternally Expressed Proteins After Parthenogenetic Activation of Buffalo Oocyte. Mol Cell Proteomics. 2018 10; 17(10):1875-1891.
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Huang YL, Wang HJ, Chen FM, Zhao XL, Fu Q, Zhang PF, Pu LP, Huang FL, Lu YQ, Zhang M. Role of BCL2L10 in regulating buffalo (Bubalus bubalis) oocyte maturation. Theriogenology. 2018 Apr 01; 110:1-7.
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Ruebel ML, Cotter M, Sims CR, Moutos DM, Badger TM, Cleves MA, Shankar K, Andres A. Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective. J Clin Endocrinol Metab. 2017 06 01; 102(6):2029-2038.
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Myers EJ, Marshall A, Jennings ML, Parker MD. Mouse Slc4a11 expressed in Xenopus oocytes is an ideally selective H+/OH- conductance pathway that is stimulated by rises in intracellular and extracellular pH. Am J Physiol Cell Physiol. 2016 Dec 01; 311(6):C945-C959.
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Iyer S, Anwari K, Alsop AE, Yuen WS, Huang DC, Carroll J, Smith NA, Smith BJ, Dewson G, Kluck RM. Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies. Nat Commun. 2016 05 24; 7:11734.
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Wang ZW, Zhang GL, Schatten H, Carroll J, Sun QY. Cytoplasmic Determination of Meiotic Spindle Size Revealed by a Unique Inter-Species Germinal Vesicle Transfer Model. Sci Rep. 2016 Jan 27; 6:19827.
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Marangos P, Stevense M, Niaka K, Lagoudaki M, Nabti I, Jessberger R, Carroll J. DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age. Nat Commun. 2015 Nov 02; 6:8706.
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Li X, Anishkin A, Liu H, van Rossum DB, Chintapalli SV, Sassic JK, Gallegos D, Pivaroff-Ward K, Jegla T. Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate. J Gen Physiol. 2015 Nov; 146(5):357-74.
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