 von Willebrand Factor
"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
| Descriptor ID |
D014841
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| MeSH Number(s) |
D12.776.124.125.920 D23.119.985
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| Concept/Terms |
von Willebrand Factor- von Willebrand Factor
- Factor VIIIR-Ag
- Factor VIIIR Ag
- Factor VIIIR-RCo
- Factor VIIIR RCo
- Ristocetin-Willebrand Factor
- Ristocetin Willebrand Factor
- von Willebrand Protein
- Factor VIII-Related Antigen
- Factor VIII Related Antigen
- Ristocetin Cofactor
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Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".
Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".
This graph shows the total number of publications written about "von Willebrand Factor" by people in UAMS Profiles by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 2 | 2 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2013 | 3 | 1 | 4 | | 2012 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2008 | 0 | 2 | 2 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2004 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "von Willebrand Factor" by people in Profiles over the past ten years.
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Pir GJ, Parray A, Ayadathil R, Pananchikkal SV, Mir FA, Muhammad I, Abubakar A, Amir N, Hussain S, Haroon KH, Muhammad A, Imam Y, Patro SN, Akhtar N, Zakaria A, Kamran S. Platelet-Neutrophil Association in NETs-Rich Areas in the Retrieved AIS Patient Thrombi. Int J Mol Sci. 2022 Nov 21; 23(22).
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Ware J. Murine models of glycoprotein Ib-IX. Platelets. 2022 Aug 18; 33(6):811-816.
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Becker RC, Sexton T, Smyth S. COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles. J Thromb Thrombolysis. 2021 Nov; 52(4):1010-1019.
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Gill JC, Conley SF, Johnson VP, Christopherson PA, Haberichter SL, Diaz CD, Strong TC, Zhang J, Simpson P, Abshire TC, Montgomery RR, Flood VH. Low VWF levels in children and lack of association with bleeding in children undergoing tonsillectomy. Blood Adv. 2020 01 14; 4(1):100-105.
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Murray GP, Post SR, Post GR. ABO blood group is a determinant of von Willebrand factor protein levels in human pulmonary endothelial cells. J Clin Pathol. 2020 Jun; 73(6):347-349.
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Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R. Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2271-2279.
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Banerjee M, Joshi S, Zhang J, Moncman CL, Yadav S, Bouchard BA, Storrie B, Whiteheart SW. Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions. Blood. 2017 12 28; 130(26):2872-2883.
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Neigh GN, Nemeth CL, Kelly SD, Hardy EE, Bourke C, Stowe ZN, Owens MJ. Prenatal stress-induced increases in hippocampal von Willebrand factor expression are prevented by concurrent prenatal escitalopram. Physiol Behav. 2017 04 01; 172:24-30.
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Zhou H, Ran Y, Da Q, Shaw TS, Shang D, Reddy AK, L?pez JA, Ballantyne CM, Ware J, Wu H, Peng Y. Defective Association of the Platelet Glycoprotein Ib-IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma Formation. J Immunol. 2016 07 01; 197(1):288-95.
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Kupchak BR, McKenzie AL, Luk HY, Saenz C, Kunces LJ, Ellis LA, Vingren JL, Lee EC, Ballard KD, Johnson EC, Kavouras SA, Ganio MS, Wingo JE, Williamson KH, Armstrong LE. Effect of cycling in the heat for 164?km on procoagulant and fibrinolytic parameters. Eur J Appl Physiol. 2015 Jun; 115(6):1295-303.
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