 Prothrombin
"Prothrombin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.
| Descriptor ID |
D011516
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| MeSH Number(s) |
D08.622.709 D12.776.124.125.800 D23.119.945
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| Concept/Terms |
Prothrombin- Prothrombin
- Factor II
- Blood Coagulation Factor II
- Differentiation Reversal Factor
- Factor, Differentiation Reversal
- Coagulation Factor II
- Factor II, Coagulation
- II, Coagulation Factor
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Below are MeSH descriptors whose meaning is more general than "Prothrombin".
Below are MeSH descriptors whose meaning is more specific than "Prothrombin".
This graph shows the total number of publications written about "Prothrombin" by people in UAMS Profiles by year, and whether "Prothrombin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Prothrombin" by people in Profiles over the past ten years.
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Rachapudi SS, Charoenkijkajorn C, Pakravan M, Lee AG. Prothrombin 20210A mutation in acute posterior cerebral artery infarction and branch retinal vein occlusion. Can J Ophthalmol. 2023 12; 58(6):e259-e262.
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Corwin HL, Shander A. Conjecture and Fact: Prothrombin Complex Concentrates for Bleeding With Vitamin K Antagonists. Crit Care Med. 2018 06; 46(6):1020-1022.
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Kupchak BR, McKenzie AL, Luk HY, Saenz C, Kunces LJ, Ellis LA, Vingren JL, Lee EC, Ballard KD, Johnson EC, Kavouras SA, Ganio MS, Wingo JE, Williamson KH, Armstrong LE. Effect of cycling in the heat for 164?km on procoagulant and fibrinolytic parameters. Eur J Appl Physiol. 2015 Jun; 115(6):1295-303.
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