Fibrinogen
"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Descriptor ID |
D005340
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MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
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Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- I, Coagulation Factor
- Factor I
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Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in UAMS Profiles by year, and whether "Fibrinogen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2019 | 0 | 1 | 1 | 2018 | 0 | 2 | 2 | 2017 | 2 | 0 | 2 | 2016 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 | 2007 | 1 | 1 | 2 | 2005 | 1 | 0 | 1 | 2004 | 1 | 0 | 1 | 2003 | 0 | 2 | 2 | 2002 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles over the past ten years.
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Ying J, Zhou D, Gu T, Huang J, Liu H. Pretreatment albumin/fibrinogen ratio as a promising predictor for the survival of advanced non small-cell lung cancer patients undergoing first-line platinum-based chemotherapy. BMC Cancer. 2019 Mar 29; 19(1):288.
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Thomasson RR, Yazer MH, Gorham JD, Dunbar NM. International assessment of massive transfusion protocol contents and indications for activation. Transfusion. 2019 05; 59(5):1637-1643.
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Morra DE, Pierson SK, Shilling D, Nemat S, Appiani C, Guilfoyle M, Tendler C, van Rhee F, Fajgenbaum DC. Predictors of response to anti-IL6 monoclonal antibody therapy (siltuximab) in idiopathic multicentric Castleman disease: secondary analyses of phase II clinical trial data. Br J Haematol. 2019 01; 184(2):232-241.
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Mattila N, Sepp?nen H, Mustonen H, Przybyla B, Haglund C, Lassila R. Preoperative Biomarker Panel, Including Fibrinogen and FVIII, Improves Diagnostic Accuracy for Pancreatic Ductal Adenocarcinoma. Clin Appl Thromb Hemost. 2018 Nov; 24(8):1267-1275.
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Mack JM, Richter GT, Crary SE. Effectiveness and Safety of Treatment with Direct Oral Anticoagulant Rivaroxaban in Patients with Slow-Flow Vascular Malformations: A Case Series. Lymphat Res Biol. 2018 06; 16(3):278-281.
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Banerjee M, Joshi S, Zhang J, Moncman CL, Yadav S, Bouchard BA, Storrie B, Whiteheart SW. Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions. Blood. 2017 12 28; 130(26):2872-2883.
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Wang J, Pathak R, Garg S, Hauer-Jensen M. Fibrinogen deficiency suppresses the development of early and delayed radiation enteropathy. World J Gastroenterol. 2017 Jul 14; 23(26):4701-4711.
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Cao XX, Sun J, Li J, Zhong DR, Niu N, Duan MH, Liang ZY, Zhou DB. Evaluation of clinicopathologic characteristics and the BRAF V600E mutation in Erdheim-Chester disease among Chinese adults. Ann Hematol. 2016 Apr; 95(5):745-50.
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Byrnes JW, Bhutta AT, Rettiganti MR, Gomez A, Garcia X, Dyamenahalli U, Johnson C, Jaquiss RD, Imamura M, Prodhan P. Steroid therapy attenuates acute phase reactant response among children on ventricular assist device support. Ann Thorac Surg. 2015 Apr; 99(4):1392-8.
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