 Intercellular Signaling Peptides and Proteins
"Intercellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
| Descriptor ID |
D036341
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| MeSH Number(s) |
D12.644.276 D12.776.467 D23.529
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Intercellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intercellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intercellular Signaling Peptides and Proteins" by people in UAMS Profiles by year, and whether "Intercellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2021 | 1 | 0 | 1 | | 2019 | 1 | 3 | 4 | | 2018 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2016 | 2 | 5 | 7 | | 2015 | 1 | 2 | 3 | | 2014 | 2 | 4 | 6 | | 2013 | 0 | 3 | 3 | | 2012 | 0 | 6 | 6 | | 2011 | 1 | 6 | 7 | | 2010 | 1 | 2 | 3 | | 2009 | 2 | 4 | 6 | | 2008 | 4 | 4 | 8 | | 2007 | 5 | 2 | 7 | | 2006 | 2 | 4 | 6 | | 2005 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2003 | 2 | 4 | 6 | | 2002 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1997 | 0 | 2 | 2 | | 1994 | 0 | 2 | 2 |
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Below are the most recent publications written about "Intercellular Signaling Peptides and Proteins" by people in Profiles over the past ten years.
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Tiwari-Heckler S, Yee EU, Yalcin Y, Park J, Nguyen DT, Gao W, Csizmadia E, Afdhal N, Mukamal KJ, Robson SC, Lai M, Schwartz RE, Jiang ZG. Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. Cell Rep. 2021 10 26; 37(4):109897.
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Reyes-Pardo H, Sánchez-Herrera DP. Mechanosensitive ion channel inhibitors promote the stiffening of the plasma membrane of mouse sensory neurons. Soft Matter. 2019 Oct 23; 15(41):8320-8328.
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Yang EJ, Hendricks AJ, Beck KM, Shi VY. Bioactive: A new era of bioactive ingredients in topical formulations for inflammatory dermatoses. Dermatol Ther. 2019 11; 32(6):e13101.
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Yeung TL, Leung CS, Yip KP, Sheng J, Vien L, Bover LC, Birrer MJ, Wong STC, Mok SC. Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer. Clin Cancer Res. 2019 11 01; 25(21):6417-6428.
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Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jähn K, Long CL, Schlüter H, Kwiatkowski M, Saini V, Pajevic PD, Bellido T, van Wijnen AJ, Mohammad KS, Guise TA, Taipaleenmäki H, Hesse E. TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone. Nat Commun. 2019 03 22; 10(1):1354.
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Jamshidi-Parsian A, Griffin RJ, Kore RA, Todorova VK, Makhoul I. Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma. Exp Cell Res. 2018 11 01; 372(1):16-24.
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Singh A, Choubey M, Bora P, Krishna A. Adiponectin and Chemerin: Contrary Adipokines in Regulating Reproduction and Metabolic Disorders. Reprod Sci. 2018 10; 25(10):1462-1473.
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Yin GN, Jin HR, Choi MJ, Limanjaya A, Ghatak K, Minh NN, Ock J, Kwon MH, Song KM, Park HJ, Kim HM, Kwon YG, Ryu JK, Suh JK. Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway. Diabetes. 2018 06; 67(6):1149-1161.
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Tamplen M, Fowler T, Markey J, Knott PD, Suva LJ, Alliston T. Treatment with anti-Sclerostin antibody to stimulate mandibular bone formation. Head Neck. 2018 07; 40(7):1453-1460.
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Ghatak K, Yin GN, Choi MJ, Limanjaya A, Minh NN, Ock J, Song KM, Kang DH, Kwon YG, Kim HM, Ryu JK, Suh JK. Dickkopf2 rescues erectile function by enhancing penile neurovascular regeneration in a mouse model of cavernous nerve injury. Sci Rep. 2017 12 19; 7(1):17819.
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Jiang ZG, Sandhu B, Feldbrügge L, Yee EU, Csizmadia E, Mitsuhashi S, Huang J, Afdhal NH, Robson SC, Lai M. Serum Activity of Macrophage-Derived Adenosine Deaminase 2 Is Associated With Liver Fibrosis in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2018 07; 16(7):1170-1172.
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Coker RH, Weaver AN, Coker MS, Murphy CJ, Gunga HC, Steinach M. Metabolic Responses to the Yukon Arctic Ultra: Longest and Coldest in the World. Med Sci Sports Exerc. 2017 02; 49(2):357-362.
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Delgado-Calle J, Tu X, Pacheco-Costa R, McAndrews K, Edwards R, Pellegrini GG, Kuhlenschmidt K, Olivos N, Robling A, Peacock M, Plotkin LI, Bellido T. Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor. J Bone Miner Res. 2017 Mar; 32(3):522-535.
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Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, Plotkin LI, Gortazar AR, Esbrit P, Bellido T. PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading. J Bone Miner Res. 2017 Mar; 32(3):486-497.
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Emanuelli T, Burgeiro A, Carvalho E. Effects of insulin on the skin: possible healing benefits for diabetic foot ulcers. Arch Dermatol Res. 2016 Dec; 308(10):677-694.
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Sato AY, Cregor M, Delgado-Calle J, Condon KW, Allen MR, Peacock M, Plotkin LI, Bellido T. Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin. J Bone Miner Res. 2016 10; 31(10):1791-1802.
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D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R. Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer. J Exp Med. 2016 05 02; 213(5):827-40.
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Larsen CP, Beggs ML, Wilson JD, Lathrop SL. Prevalence and organ distribution of leukocyte chemotactic factor 2 amyloidosis (ALECT2) among decedents in New Mexico. Amyloid. 2016 Jun; 23(2):119-23.
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Goyal S, Hamrah P. Understanding Neuropathic Corneal Pain--Gaps and Current Therapeutic Approaches. Semin Ophthalmol. 2016; 31(1-2):59-70.
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Niziolek PJ, MacDonald BT, Kedlaya R, Zhang M, Bellido T, He X, Warman ML, Robling AG. High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo. J Bone Miner Res. 2015 Oct; 30(10):1822-30.
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Slikker W, Liu F, Rainosek SW, Patterson TA, Sadovova N, Hanig JP, Paule MG, Wang C. Ketamine-Induced Toxicity in Neurons Differentiated from Neural Stem Cells. Mol Neurobiol. 2015 Oct; 52(2):959-69.
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Wolfe AR, Atkinson RL, Reddy JP, Debeb BG, Larson R, Li L, Masuda H, Brewer T, Atkinson BJ, Brewster A, Ueno NT, Woodward WA. High-density and very-low-density lipoprotein have opposing roles in regulating tumor-initiating cells and sensitivity to radiation in inflammatory breast cancer. Int J Radiat Oncol Biol Phys. 2015 Apr 01; 91(5):1072-80.
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Wang P, Du H, Zhou CC, Song J, Liu X, Cao X, Mehta JL, Shi Y, Su DF, Miao CY. Intracellular NAMPT-NAD+-SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors. Cardiovasc Res. 2014 Dec 01; 104(3):477-88.
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Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014 Oct 03; 5:5092.
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Ryu S, Lee Y, Hyun MY, Choi SY, Jeong KH, Park YM, Kang H, Park KY, Armstrong CA, Johnson A, Song PI, Kim BJ. Mycophenolate antagonizes IFN-?-induced catagen-like changes via ß-catenin activation in human dermal papilla cells and hair follicles. Int J Mol Sci. 2014 Sep 22; 15(9):16800-15.
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Evanson JR, Guyton MK, Oliver DL, Hire JM, Topolski RL, Zumbrun SD, McPherson JC, Bojescul JA. Gender and age differences in growth factor concentrations from platelet-rich plasma in adults. Mil Med. 2014 Jul; 179(7):799-805.
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Artsi H, Cohen-Kfir E, Gurt I, Shahar R, Bajayo A, Kalish N, Bellido TM, Gabet Y, Dresner-Pollak R. The Sirtuin1 activator SRT3025 down-regulates sclerostin and rescues ovariectomy-induced bone loss and biomechanical deterioration in female mice. Endocrinology. 2014 Sep; 155(9):3508-15.
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Larsen CP, Kossmann RJ, Beggs ML, Solomon A, Walker PD. Clinical, morphologic, and genetic features of renal leukocyte chemotactic factor 2 amyloidosis. Kidney Int. 2014 Aug; 86(2):378-82.
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Rhee Y, Lee EY, Lezcano V, Ronda AC, Condon KW, Allen MR, Plotkin LI, Bellido T. Resorption controls bone anabolism driven by parathyroid hormone (PTH) receptor signaling in osteocytes. J Biol Chem. 2013 Oct 11; 288(41):29809-20.
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Bailey AR, Hou H, Song M, Obregon DF, Portis S, Barger S, Shytle D, Stock S, Mori T, Sanberg PG, Murphy T, Tan J. GFAP expression and social deficits in transgenic mice overexpressing human sAPPa. Glia. 2013 Sep; 61(9):1556-69.
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