A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Descriptor ID	D007611
MeSH Number(s)	D12.776.083
Concept/Terms	Aprotinin Aprotinin Bovine Kunitz Pancreatic Trypsin Inhibitor Bovine Pancreatic Trypsin Inhibitor Trypsin Inhibitor, Kunitz, Pancreatic Kallikrein-Trypsin Inactivator Inactivator, Kallikrein-Trypsin Kallikrein Trypsin Inactivator Kunitz Pancreatic Trypsin Inhibitor Trypsin Inhibitor, Basic, Pancreatic Basic Pancreatic Trypsin Inhibitor BPTI, Basic Pancreatic Trypsin Inhibitor Contrykal Contrykal Kontrykal Kontrikal Arzneimittelwerk Dresden Brand of Aprotinin Contrical Dilmintal Dilmintal Iniprol Iniprol Sanofi Winthrop Brand of Aprotinin Zymofren Zymofren Traskolan Traskolan Trasylol Trasylol Bayer Brand of Aprotinin Antilysin Antilysin Pulmin Pulmin

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Below are MeSH descriptors whose meaning is more specific than "Aprotinin".