Amyloid
"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
Descriptor ID |
D000682
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MeSH Number(s) |
D05.500.049 D12.776.049
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Concept/Terms |
Amyloid- Amyloid
- Amyloid Substance
- Substance, Amyloid
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Below are MeSH descriptors whose meaning is more general than "Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Amyloid".
This graph shows the total number of publications written about "Amyloid" by people in UAMS Profiles by year, and whether "Amyloid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 1 | 2 | 3 | 2022 | 0 | 1 | 1 | 2021 | 0 | 1 | 1 | 2020 | 1 | 2 | 3 | 2019 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 | 2017 | 2 | 1 | 3 | 2016 | 2 | 2 | 4 | 2015 | 2 | 0 | 2 | 2014 | 2 | 1 | 3 | 2013 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2008 | 0 | 1 | 1 | 2004 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amyloid" by people in Profiles over the past ten years.
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Ozdag Y, Koshinski JL, Carry BJ, Gardner JM, Garcia VC, Dwyer CL, Klena JC, Grandizio LC. A Comparison of Tenosynovial and Transverse Carpal Ligament Biopsy for Amyloid Detection in Open Carpal Tunnel Release. J Hand Surg Am. 2024 Oct; 49(10):979-985.
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Wong S, West ME, Morgan GJ. Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains. Protein Sci. 2024 Mar; 33(3):e4871.
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Young CB, Smith V, Karjadi C, Grogan SM, Ang TFA, Insel PS, Henderson VW, Sumner M, Poston KL, Au R, Mormino EC. Speech patterns during memory recall relates to early tau burden across adulthood. Alzheimers Dement. 2024 04; 20(4):2552-2563.
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Rosen AC, Arias JJ, Ashford JW, Blacker D, Chhatwal JP, Chin NA, Clark L, Denny SS, Goldman JS, Gleason CE, Grill JD, Heidebrink JL, Henderson VW, Lavacot JA, Lingler JH, Menon M, Nosheny RL, Oliveira FF, Parker MW, Rahman-Filipiak A, Revoori A, Rumbaugh MC, Sanchez DL, Schindler SE, Schwarz CG, Toy L, Tyrone J, Walter S, Wang LS, Wijsman EM, Zallen DT, Aggarwal NT. The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All. J Alzheimers Dis. 2022; 90(3):953-962.
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Morgan GJ. Transient disorder along pathways to amyloid. Biophys Chem. 2022 02; 281:106711.
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Gokden M. Amyloid Deposition in the Brain. Arch Pathol Lab Med. 2020 10 01; 144(10):1162-1163.
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Morgan GJ, Wall JS. The Process of Amyloid Formation due to Monoclonal Immunoglobulins. Hematol Oncol Clin North Am. 2020 12; 34(6):1041-1054.
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Arya S, Ganguly P, Arsiccio A, Claud SL, Trapp B, Schonfeld GE, Liu X, Lazar Cantrell K, Shea JE, Bowers MT. Terminal Capping of an Amyloidogenic Tau Fragment Modulates Its Fibrillation Propensity. J Phys Chem B. 2020 10 08; 124(40):8772-8783.
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Karamanos TK, Jackson MP, Calabrese AN, Goodchild SC, Cawood EE, Thompson GS, Kalverda AP, Hewitt EW, Radford SE. Structural mapping of oligomeric intermediates in an amyloid assembly pathway. Elife. 2019 09 25; 8.
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Iadanza MG, Jackson MP, Hewitt EW, Ranson NA, Radford SE. A new era for understanding amyloid structures and disease. Nat Rev Mol Cell Biol. 2018 12; 19(12):755-773.
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Palmer BW, Harmell AL, Dunn LB, Kim SY, Pinto LL, Golshan S, Jeste DV. Multimedia Aided Consent for Alzheimer's Disease Research. Clin Gerontol. 2018 Jan-Feb; 41(1):20-32.
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Jackson MP, Hewitt EW. Why are Functional Amyloids Non-Toxic in Humans? Biomolecules. 2017 09 22; 7(4).
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Giffin JC, Richards RC, Craft C, Jahan N, Leggiadro C, Chopin T, Szemerda M, MacKinnon SL, Ewart KV. An extract of the marine alga Alaria esculenta modulates a-synuclein folding and amyloid formation. Neurosci Lett. 2017 03 22; 644:87-93.
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Jackson MP, Hewitt EW. Cellular proteostasis: degradation of misfolded proteins by lysosomes. Essays Biochem. 2016 10 15; 60(2):173-180.
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Morgan GJ, Kelly JW. The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains. J Mol Biol. 2016 10 23; 428(21):4280-4297.
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Larsen CP, Beggs ML, Wilson JD, Lathrop SL. Prevalence and organ distribution of leukocyte chemotactic factor 2 amyloidosis (ALECT2) among decedents in New Mexico. Amyloid. 2016 Jun; 23(2):119-23.
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Iadanza MG, Jackson MP, Radford SE, Ranson NA. MpUL-multi: Software for Calculation of Amyloid Fibril Mass per Unit Length from TB-TEM Images. Sci Rep. 2016 Feb 12; 6:21078.
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Chouchane K, Vendrely C, Amari M, Moreaux K, Bruckert F, Weidenhaupt M. Dual Effect of (LK)nL Peptides on the Onset of Insulin Amyloid Fiber Formation at Hydrophobic Surfaces. J Phys Chem B. 2015 Aug 20; 119(33):10543-53.
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Do TD, Chamas A, Zheng X, Barnes A, Chang D, Veldstra T, Takhar H, Dressler N, Trapp B, Miller K, McMahon A, Meredith SC, Shea JE, Lazar Cantrell K, Bowers MT. Elucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation. Biochemistry. 2015 Jul 07; 54(26):4050-62.
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