 Receptors, Notch
"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.
| Descriptor ID |
D051880
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| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.670
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in UAMS Profiles by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2016 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2014 | 4 | 0 | 4 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Notch" by people in Profiles over the past ten years.
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Delgado-Calle J, McAndrews K, Wu G, Orr AL, Ferrari A, Tu X, Srinivasan V, Roodman GD, Ebetino FH, Boeckman RK, Bellido T. The Notch pathway regulates the bone gain induced by PTH anabolic signaling. FASEB J. 2022 03; 36(3):e22196.
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Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK, Roodman GD, Bellido T, Delgado-Calle J. Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity. Cancer Res. 2021 10 01; 81(19):5102-5114.
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Zhang H, Wei T, Johnson A, Sun R, Richter G, Strub GM. NOTCH pathway activation in infantile hemangiomas. J Vasc Surg Venous Lymphat Disord. 2021 03; 9(2):489-496.
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Silva C, Sampaio-Pinto V, Andrade S, Rodrigues I, Costa R, Guerreiro S, Carvalho E, Pinto-do-? P, Nascimento DS, Soares R. Establishing a Link between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model. Cell Physiol Biochem. 2019; 52(3):503-516.
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So J, Khaliq M, Evason K, Ninov N, Martin BL, Stainier DYR, Shin D. Wnt/?-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating notch activity. Hepatology. 2018 06; 67(6):2352-2366.
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Allam H, Johnson BP, Zhang M, Lu Z, Cannon MJ, Abbott KL. The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer. J Biol Chem. 2017 09 29; 292(39):16351-16359.
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Sato AY, Richardson D, Cregor M, Davis HM, Au ED, McAndrews K, Zimmers TA, Organ JM, Peacock M, Plotkin LI, Bellido T. Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases. Endocrinology. 2017 03 01; 158(3):664-677.
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Hassed S, Li S, Mulvihill J, Aston C, Palmer S. Adams-Oliver syndrome review of the literature: Refining the diagnostic phenotype. Am J Med Genet A. 2017 Mar; 173(3):790-800.
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Delgado-Calle J, Anderson J, Cregor MD, Hiasa M, Chirgwin JM, Carlesso N, Yoneda T, Mohammad KS, Plotkin LI, Roodman GD, Bellido T. Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma. Cancer Res. 2016 Mar 01; 76(5):1089-100.
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Mehta JL, Mercanti F, Stone A, Wang X, Ding Z, Romeo F, Khaidakov M. Gene and microRNA transcriptional signatures of angiotensin II in endothelial cells. J Cardiovasc Pharmacol. 2015 Feb; 65(2):123-9.
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