NFATC Transcription Factors
"NFATC Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
Descriptor ID |
D050778
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MeSH Number(s) |
D12.776.930.608
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Concept/Terms |
NFATC Transcription Factors- NFATC Transcription Factors
- Transcription Factors, NFATC
- NFAT Proteins
- Transcription Factor NF-AT
- NF-AT, Transcription Factor
- Transcription Factor NF AT
- Nuclear Factor of Activated T-Cells, Cytoplasmic
- Nuclear Factor of Activated T Cells, Cytoplasmic
- Nuclear Factors of Activated T-Cells
- Nuclear Factors of Activated T Cells
- NF-AT Proteins
- NF AT Proteins
- NFATC Proteins
NFAT Transcription Factor 4- NFAT Transcription Factor 4
- NFAT4 Protein
- Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein
- Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein
- NFATC3 Transcription Factor
- Factor, NFATC3 Transcription
- Transcription Factor, NFATC3
- NFATx Protein
- NF-AT4 Protein
- NF AT4 Protein
- NFATC3 Protein
NFAT Transcription Factor 2- NFAT Transcription Factor 2
- NFAT-2 Protein
- NFAT 2 Protein
- Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein
- Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein
- NFATC1 Protein
- NFATC1 Transcription Factor
- Factor, NFATC1 Transcription
- Transcription Factor, NFATC1
- NF-ATc1 Protein
- NF ATc1 Protein
- NFAT2 Protein
NFAT Transcription Factor 3- NFAT Transcription Factor 3
- NFATC4 Transcription Factor
- Transcription Factor, NFATC4
- NFAT3 Protein
- NFATC4 Protein
- Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein
- Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein
- NF-AT3 Protein
- NF AT3 Protein
NFAT Transcription Factor 5- NFAT Transcription Factor 5
- Nuclear Factor of Activated T-Cells 5 Protein
- Nuclear Factor of Activated T Cells 5 Protein
- OREBP Protein
- Osmotic Response Element Binding Protein
- NFATL1 Protein
- Tonicity-Responsive Enhancer-Binding Protein
- Tonicity Responsive Enhancer Binding Protein
- NFAT5 Protein
- NFATz Protein
- TonEBP Protein
NFAT Transcription Factor 1- NFAT Transcription Factor 1
- NFATC2 Transcription Factor
- Factor, NFATC2 Transcription
- Transcription Factor, NFATC2
- NFAT1 Protein
- NFATC2 Protein
- Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein
- Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein
- NFAT-1 Protein
- NFAT 1 Protein
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Below are MeSH descriptors whose meaning is more general than "NFATC Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "NFATC Transcription Factors".
This graph shows the total number of publications written about "NFATC Transcription Factors" by people in UAMS Profiles by year, and whether "NFATC Transcription Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2018 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2014 | 0 | 2 | 2 | 2013 | 1 | 1 | 2 | 2012 | 0 | 1 | 1 | 2009 | 0 | 3 | 3 | 2007 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2000 | 0 | 2 | 2 | 1999 | 0 | 1 | 1 | 1998 | 0 | 2 | 2 | 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "NFATC Transcription Factors" by people in Profiles over the past ten years.
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Lionikaite V, Westerlund A, Conaway HH, Henning P, Lerner UH. Effects of retinoids on physiologic and inflammatory osteoclastogenesis in vitro. J Leukoc Biol. 2018 12; 104(6):1133-1145.
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Kim Wiese A, Schluterman Burdine M, Turnage RH, Tackett AJ, Burdine LJ. DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes. PLoS One. 2017; 12(7):e0181608.
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Fujiwara T, Zhou J, Ye S, Zhao H. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival. Cell Death Dis. 2016 07 21; 7:e2300.
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