 Pro-Opiomelanocortin
"Pro-Opiomelanocortin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
| Descriptor ID |
D011333
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| MeSH Number(s) |
D06.472.699.327.935 D06.472.699.631.525.600 D12.644.400.400.935 D12.644.548.365.935 D12.644.548.691.525.690 D12.776.641.650.405.935 D12.776.811.800
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| Concept/Terms |
Pro-Opiomelanocortin- Pro-Opiomelanocortin
- Pro Opiomelanocortin
- ACTH-Endorphin Precursor
- ACTH Endorphin Precursor
- Corticotropin-beta-Lipotropin Precursor
- Corticotropin beta Lipotropin Precursor
- Endorphin-ACTH Precursor
- Endorphin ACTH Precursor
- Proopiomelanocortin
- Pro-ACTH-Endorphin
- Pro ACTH Endorphin
- Pro-Opio-Melanocortin
- Pro Opio Melanocortin
- Pro-Opiocortin
- Pro Opiocortin
- Proopiocortin
- ACTH-beta-Lipotropin Precursor
- ACTH beta Lipotropin Precursor
- POMC
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Below are MeSH descriptors whose meaning is more general than "Pro-Opiomelanocortin".
Below are MeSH descriptors whose meaning is more specific than "Pro-Opiomelanocortin".
This graph shows the total number of publications written about "Pro-Opiomelanocortin" by people in UAMS Profiles by year, and whether "Pro-Opiomelanocortin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 |
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Below are the most recent publications written about "Pro-Opiomelanocortin" by people in Profiles over the past ten years.
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Baldini G, Phelan KD. The melanocortin pathway and control of appetite-progress and therapeutic implications. J Endocrinol. 2019 04 01; 241(1):R1-R33.
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Nyamugenda E, Trentzsch M, Russell S, Miles T, Boysen G, Phelan KD, Baldini G. Injury to hypothalamic Sim1 neurons is a common feature of obesity by exposure to high-fat diet in male and female mice. J Neurochem. 2019 04; 149(1):73-97.
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