 Ribosomal Protein S6 Kinases
"Ribosomal Protein S6 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.
| Descriptor ID |
D019893
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| MeSH Number(s) |
D08.811.913.696.620.682.700.862 D12.644.360.600 D12.776.476.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6 Kinases".
Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6 Kinases".
This graph shows the total number of publications written about "Ribosomal Protein S6 Kinases" by people in UAMS Profiles by year, and whether "Ribosomal Protein S6 Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribosomal Protein S6 Kinases" by people in Profiles over the past ten years.
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Khalil MI, Ismail HM, Panasyuk G, Bdzhola A, Filonenko V, Gout I, Pardo OE. Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function. Int J Mol Sci. 2023 May 15; 24(10).
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Li Y, Cooper A, Odibo IN, Ahmed A, Murphy P, Koonce R, Dajani NK, Lowery CL, Roberts DJ, Maroteaux L, Kilic F. Discrepancy in Insulin Regulation between Gestational Diabetes Mellitus (GDM) Platelets and Placenta. J Biol Chem. 2016 Apr 29; 291(18):9657-65.
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