 Serotonin Plasma Membrane Transport Proteins
"Serotonin Plasma Membrane Transport Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.
| Descriptor ID |
D050486
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| MeSH Number(s) |
D12.776.157.530.450.625.311 D12.776.157.530.562.374.875 D12.776.543.585.450.625.374 D12.776.543.585.562.374.875
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| Concept/Terms |
Serotonin Plasma Membrane Transport Proteins- Serotonin Plasma Membrane Transport Proteins
- 5HT Transporter
- Neurotransmitter Transport Proteins, Serotonin-Specific
- Neurotransmitter Transport Proteins, Serotonin Specific
- Sodium-Dependent Serotonin Transporter
- Serotonin Transporter, Sodium-Dependent
- Sodium Dependent Serotonin Transporter
- Transporter, Sodium-Dependent Serotonin
- Serotonin Plasma Membrane Transporter Proteins
- Serotonin Transporter
- Transporter, Serotonin
- SERT Proteins
- 5-Hydroxytryptamine Plasma Membrane Transport Protein
- 5 Hydroxytryptamine Plasma Membrane Transport Protein
- Neurotransmitter Transporters, Serotonin-Specific
- Neurotransmitter Transporters, Serotonin Specific
- Serotonin-Specific Neurotransmitter Transporters
- Transporters, Serotonin-Specific Neurotransmitter
Serotonectin- Serotonectin
- Serotonin Transporter, Platelets
- Platelets Serotonin Transporter
- Transporter, Platelets Serotonin
- Platelet Serotonin Transporter
- Serotonin Transporter, Platelet
- Transporter, Platelet Serotonin
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Below are MeSH descriptors whose meaning is more general than "Serotonin Plasma Membrane Transport Proteins".
Below are MeSH descriptors whose meaning is more specific than "Serotonin Plasma Membrane Transport Proteins".
This graph shows the total number of publications written about "Serotonin Plasma Membrane Transport Proteins" by people in UAMS Profiles by year, and whether "Serotonin Plasma Membrane Transport Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2012 | 2 | 0 | 2 | | 2011 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2006 | 1 | 1 | 2 | | 2004 | 0 | 2 | 2 | | 2003 | 0 | 3 | 3 | | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serotonin Plasma Membrane Transport Proteins" by people in Profiles over the past ten years.
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Fitzgerald LR, Gannon BM, Walther D, Landavazo A, Hiranita T, Blough BE, Baumann MH, Fantegrossi WE. Structure-activity relationships for locomotor stimulant effects and monoamine transporter interactions of substituted amphetamines and cathinones. Neuropharmacology. 2024 Mar 01; 245:109827.
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Kilic F. The nature of the binding between insulin receptor and serotonin transporter in placenta (review). Placenta. 2023 03 03; 133:40-44.
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Maier J, Rauter L, Rudin D, Niello M, Holy M, Schmid D, Wilson J, Blough BE, Gannon BM, Murnane KS, Sitte HH. a-PPP and its derivatives are selective partial releasers at the human norepinephrine transporter: A pharmacological characterization of interactions between pyrrolidinopropiophenones and high and low affinity monoamine transporters. Neuropharmacology. 2021 06 01; 190:108570.
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Cooper A, Woulfe D, Kilic F. Post-translational modifications of serotonin transporter. Pharmacol Res. 2019 02; 140:7-13.
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Tuominen L, Miettunen J, Cannon DM, Drevets WC, Frokjaer VG, Hirvonen J, Ichise M, Jensen PS, Keltikangas-J?rvinen L, Klaver JM, Knudsen GM, Takano A, Suhara T, Hietala J. Neuroticism Associates with Cerebral in Vivo Serotonin Transporter Binding Differently in Males and Females. Int J Neuropsychopharmacol. 2017 12 01; 20(12):963-970.
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Hankosky ER, Joolakanti SR, Nickell JR, Janganati V, Dwoskin LP, Crooks PA. Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [3H]dopamine uptake at the vesicular monoamine transporter-2. Bioorg Med Chem Lett. 2017 12 15; 27(24):5467-5472.
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Hadden C, Fahmi T, Cooper A, Savenka AV, Lupashin VV, Roberts DJ, Maroteaux L, Hauguel-de Mouzon S, Kilic F. Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway. J Cell Physiol. 2017 Dec; 232(12):3520-3529.
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Joolakanti SR, Nickell JR, Janganati V, Zheng G, Dwoskin LP, Crooks PA. Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2. Bioorg Med Chem Lett. 2016 05 15; 26(10):2422-2427.
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Li Y, Cooper A, Odibo IN, Ahmed A, Murphy P, Koonce R, Dajani NK, Lowery CL, Roberts DJ, Maroteaux L, Kilic F. Discrepancy in Insulin Regulation between Gestational Diabetes Mellitus (GDM) Platelets and Placenta. J Biol Chem. 2016 Apr 29; 291(18):9657-65.
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Helton SG, Lohoff FW. Serotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders. Pharmacogenomics. 2015; 16(5):541-53.
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Li Y, Hadden C, Singh P, Mercado CP, Murphy P, Dajani NK, Lowery CL, Roberts DJ, Maroteaux L, Kilic F. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):E5697-705.
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