 Receptors, Adrenergic, alpha-2
"Receptors, Adrenergic, alpha-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
| Descriptor ID |
D018341
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| MeSH Number(s) |
D12.776.543.750.070.300.300.300.725 D12.776.543.750.100.150.300.300.725 D12.776.543.750.720.300.300.300.300.200
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| Concept/Terms |
Receptors, Adrenergic, alpha-2- Receptors, Adrenergic, alpha-2
- Adrenergic Receptor, alpha-2
- Adrenergic Receptor, alpha 2
- Receptor, alpha-2 Adrenergic
- alpha-2 Adrenergic Receptor
- Receptors, alpha-2 Adrenergic
- Receptors, alpha 2 Adrenergic
- alpha-2 Adrenergic Receptors
- Adrenergic Receptors, alpha-2
- Receptor, Adrenergic, alpha-2
- Adrenergic alpha-2 Receptors
- Adrenergic alpha 2 Receptors
- Receptors, Adrenergic alpha-2
- alpha-2 Receptors, Adrenergic
- alpha 2 Adrenergic Receptors
Receptor, Adrenergic, alpha-2D- Receptor, Adrenergic, alpha-2D
- Receptors, Adrenergic, alpha-2D
- alpha-2D Adrenergic Receptor
- Adrenergic Receptor, alpha-2D
- Receptor, alpha-2D Adrenergic
- alpha 2D Adrenergic Receptor
- Adrenergic alpha-2D Receptors
- Adrenergic alpha 2D Receptors
- Receptors, Adrenergic alpha-2D
- alpha-2D Receptors, Adrenergic
- Adrenergic Receptor alpha(2d)
Receptor, Adrenergic, alpha-2C- Receptor, Adrenergic, alpha-2C
- alpha-2C Adrenergic Receptor
- Adrenergic Receptor, alpha-2C
- Receptor, alpha-2C Adrenergic
- alpha 2C Adrenergic Receptor
- Adrenergic Receptor alpha-2C
- Adrenergic Receptor alpha 2C
- Receptor alpha-2C, Adrenergic
- alpha-2C, Adrenergic Receptor
- Adrenergic alpha-2C Receptors
- Adrenergic alpha 2C Receptors
- Receptors, Adrenergic alpha-2C
- alpha-2C Receptors, Adrenergic
- Adrenergic Receptor alpha(2C)
Receptor, Adrenergic, alpha-2A- Receptor, Adrenergic, alpha-2A
- alpha-2A Adrenergic Receptor
- Adrenergic Receptor, alpha-2A
- Receptor, alpha-2A Adrenergic
- alpha 2A Adrenergic Receptor
- Receptors, Adrenergic, alpha-2A
- Adrenergic alpha-2A Receptors
- Adrenergic alpha 2A Receptors
- Receptors, Adrenergic alpha-2A
- alpha-2A Receptors, Adrenergic
Receptor, Adrenergic, alpha-2B- Receptor, Adrenergic, alpha-2B
- Receptors, Adrenergic, alpha-2B
- alpha-2B Adrenergic Receptor
- Adrenergic Receptor, alpha-2B
- Receptor, alpha-2B Adrenergic
- alpha 2B Adrenergic Receptor
- Adrenergic alpha-2B Receptors
- Adrenergic alpha 2B Receptors
- Receptors, Adrenergic alpha-2B
- alpha-2B Receptors, Adrenergic
- Adrenergic Receptor alpha-2b
- Adrenergic Receptor alpha 2b
- Receptor alpha-2b, Adrenergic
- alpha-2b, Adrenergic Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha-2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Catecholamine [D12.776.543.750.070.300]
- Receptors, Adrenergic [D12.776.543.750.070.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.070.300.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.070.300.300.300.725]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.100.150.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.100.150.300.300.725]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Catecholamine [D12.776.543.750.720.300.300]
- Receptors, Adrenergic [D12.776.543.750.720.300.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.300.300.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.720.300.300.300.300.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha-2".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha-2" by people in UAMS Profiles by year, and whether "Receptors, Adrenergic, alpha-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha-2" by people in Profiles over the past ten years.
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Obeng S, Crowley ML, Mottinelli M, Le?n F, Zuarth Gonzalez JD, Chen Y, Gamez-Jimenez LR, Restrepo LF, Ho NP, Patel A, Martins Rocha J, Alvarez MA, Thadisetti AM, Park CR, Pallares VLC, Milner MJ, Canal CE, Hampson AJ, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic a2 receptor activity in vitro and in vivo. Eur J Pharmacol. 2024 Oct 05; 980:176863.
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Parks BJ, Salazar P, Morrison L, McGraw MK, Gunnell M, Tobacyk J, Brents LK, Berquist MD. Limited bedding and nesting increases ethanol drinking in female rats. Pharmacol Biochem Behav. 2024 Jun; 239:173756.
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Obeng S, Leon F, Patel A, Zuarth Gonzalez JD, Chaves Da Silva L, Restrepo LF, Gamez-Jimenez LR, Ho NP, Guerrero Calvache MP, Pallares VLC, Helmes JA, Shiomitsu SK, Soto PL, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. Interactive Effects of ?-Opioid and Adrenergic-a2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine. J Pharmacol Exp Ther. 2022 12; 383(3):182-198.
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Prus AJ, Mooney-Leber SM, Berquist MD, Pehrson AL, Porter NP, Porter JH. The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats: enhancement of fluoxetine's effects by the a2 adrenoceptor antagonist yohimbine. Behav Pharmacol. 2015 Aug; 26(5):489-94.
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