 Platelet Activation
"Platelet Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
| Descriptor ID |
D015539
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| MeSH Number(s) |
G09.188.124.560.600
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| Concept/Terms |
Platelet Activation- Platelet Activation
- Activation, Platelet
- Activations, Platelet
- Platelet Activations
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Below are MeSH descriptors whose meaning is more general than "Platelet Activation".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activation".
This graph shows the total number of publications written about "Platelet Activation" by people in UAMS Profiles by year, and whether "Platelet Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2020 | 2 | 0 | 2 | | 2019 | 0 | 2 | 2 | | 2017 | 1 | 1 | 2 | | 2016 | 4 | 1 | 5 | | 2015 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2013 | 0 | 2 | 2 | | 2012 | 2 | 2 | 4 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Platelet Activation" by people in Profiles over the past ten years.
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Corken A, Wahl EC, Sikes JD, Thakali KM. Western Diet Modifies Platelet Activation Profiles in Male Mice. Int J Mol Sci. 2024 Jul 23; 25(15).
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Xiang B, Zhang G, Zhang Y, Wu C, Joshi S, Morris AJ, Ware J, Smyth SS, Whiteheart SW, Li Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):234-249.
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Pokrovskaya ID, Tobin M, Desai R, Joshi S, Kamykowski JA, Zhang G, Aronova MA, Whiteheart SW, Leapman RD, Storrie B. Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis. Platelets. 2021 Jan 02; 32(1):97-104.
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Zwifelhofer NMJ, Bercovitz RS, Cole R, Yan K, Simpson PM, Moroi A, Newman PJ, Niebler RA, Scott JP, Stuth EAD, Woods RK, Benson DW, Newman DK. Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding. Thromb Haemost. 2020 Jan; 120(1):94-106.
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Jain N, Wan F, Kothari M, Adelodun A, Ware J, Sarode R, Hedayati SS. Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial. BMC Nephrol. 2019 10 29; 20(1):395.
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Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R. Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2017 12; 37(12):2271-2279.
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Lowery CL, Elliott C, Cooper A, Hadden C, Sonon RN, Azadi P, Williams DK, Marsh JD, Woulfe DS, Kilic F. Cigarette Smoking-Associated Alterations in Serotonin/Adrenalin Signaling Pathways of Platelets. J Am Heart Assoc. 2017 May 18; 6(5).
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Kaur H, Corscadden K, Ware J, Othman M. Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease. Thromb Haemost. 2017 02 28; 117(3):543-555.
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Brice AE, Hernandez GA, Sanchez M, Haynick M, Mendoza CE. In-stent thrombosis when switching ticagrelor to clopidogrel after percutaneous coronary intervention. Platelets. 2017 May; 28(3):305-309.
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Storrie B. A tip of the cap to procoagulant platelets. Blood. 2016 09 29; 128(13):1668-9.
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Pokrovskaya ID, Aronova MA, Kamykowski JA, Prince AA, Hoyne JD, Calco GN, Kuo BC, He Q, Leapman RD, Storrie B. STEM tomography reveals that the canalicular system and a-granules remain separate compartments during early secretion stages in blood platelets. J Thromb Haemost. 2016 Mar; 14(3):572-84.
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Ware J. A binding relationship with thrombin. Blood. 2016 Feb 04; 127(5):525-6.
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Xiang B, Zhang G, Ye S, Zhang R, Huang C, Liu J, Tao M, Ruan C, Smyth SS, Whiteheart SW, Li Z. Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 2015 Dec 15; 132(24):2334-44.
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Ouseph MM, Huang Y, Banerjee M, Joshi S, MacDonald L, Zhong Y, Liu H, Li X, Xiang B, Zhang G, Komatsu M, Komatsu M, Yue Z, Li Z, Storrie B, Whiteheart SW, Wang QJ. Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis. Blood. 2015 Sep 03; 126(10):1224-33.
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