 Complement Factor B
"Complement Factor B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
| Descriptor ID |
D011415
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| MeSH Number(s) |
D08.622.200 D08.811.277.656.300.760.198 D08.811.277.656.959.350.198 D12.776.124.486.274.900
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| Concept/Terms |
Complement Factor B- Complement Factor B
- Factor B, Complement
- C3PA
- Complement 3 Proactivator
- Proactivator, Complement 3
- Complement Factor B, Alternative Pathway
- Properdin Factor B
- Factor B, Properdin
- Complement Protein Factor B
- Factor B
- C3 Proactivator
- Proactivator, C3
- Complement Protein B
- Protein B, Complement
Complement Factor Bb- Complement Factor Bb
- Bb, Complement Factor
- Factor Bb, Complement
- Properdin Factor Bb
- Factor Bb, Properdin
- Complement Factor B-Derived Fragment Bb
- Complement Factor B Derived Fragment Bb
- Bb Fragment of Factor B
- Complement Factor B Fragment, Bb
Complement Factor Ba- Complement Factor Ba
- Factor Ba, Complement
- Properdin Factor Ba
- Factor Ba, Properdin
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Below are MeSH descriptors whose meaning is more general than "Complement Factor B".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor B".
This graph shows the total number of publications written about "Complement Factor B" by people in UAMS Profiles by year, and whether "Complement Factor B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement Factor B" by people in Profiles over the past ten years.
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Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 11; 72(11):2068-2080.
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Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M. SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol. 2021 04 07; 6(58).
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