 NF-kappa B
"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
|
| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
|
| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
|
Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in UAMS Profiles by year, and whether "NF-kappa B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 4 | 4 | | 2022 | 1 | 3 | 4 | | 2021 | 2 | 6 | 8 | | 2020 | 1 | 1 | 2 | | 2019 | 2 | 2 | 4 | | 2018 | 2 | 6 | 8 | | 2017 | 2 | 7 | 9 | | 2016 | 6 | 3 | 9 | | 2015 | 2 | 12 | 14 | | 2014 | 3 | 8 | 11 | | 2013 | 3 | 9 | 12 | | 2012 | 1 | 6 | 7 | | 2011 | 8 | 10 | 18 | | 2010 | 10 | 10 | 20 | | 2009 | 6 | 7 | 13 | | 2008 | 3 | 3 | 6 | | 2007 | 7 | 11 | 18 | | 2006 | 8 | 10 | 18 | | 2005 | 2 | 4 | 6 | | 2004 | 5 | 5 | 10 | | 2003 | 2 | 4 | 6 | | 2002 | 3 | 3 | 6 | | 2001 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 1999 | 6 | 1 | 7 | | 1998 | 2 | 0 | 2 | | 1996 | 2 | 0 | 2 | | 1995 | 3 | 1 | 4 | | 1994 | 1 | 1 | 2 | | 1993 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "NF-kappa B" by people in Profiles over the past ten years.
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Liu S, Wu J, Stolarz A, Zhang H, Boerma M, Byrum SD, Rusch NJ, Ding Z. PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging. Theranostics. 2023; 13(9):2914-2929.
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Varisco BM. Nuclear Factor-?B Keeps Basal Cells Undifferentiated in Congenital Diaphragmatic Hernia. Am J Respir Crit Care Med. 2023 05 01; 207(9):1122-1123.
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Li J, Zhou Y, Zhao W, Liu J, Ullah R, Fang P, Fang L, Xiao S. Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity. Autophagy. 2023 Aug; 19(8):2257-2274.
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Muffels IJJ, Schene IF, Rehmann H, Massink MPG, van der Wal MM, Bauder C, Labeur M, Armando NG, Lequin MH, Houben ML, Giltay JC, Haitjema S, Huisman A, Vansenne F, Bluvstein J, Pappas J, Shailee LV, Zarate YA, Mokry M, van Haaften GW, Nieuwenhuis EES, Refojo D, van Wijk F, Fuchs SA, van Hasselt PM. Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration. Am J Hum Genet. 2023 01 05; 110(1):146-160.
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Bodansky A, Vazquez SE, Chou J, Novak T, Al-Musa A, Young C, Newhams M, Kucukak S, Zambrano LD, Mitchell A, Wang CY, Moffitt K, Halasa NB, Loftis LL, Schwartz SP, Walker TC, Mack EH, Fitzgerald JC, Gertz SJ, Rowan CM, Irby K, Sanders RC, Kong M, Schuster JE, Staat MA, Zinter MS, Cvijanovich NZ, Tarquinio KM, Coates BM, Flori HR, Dahmer MK, Crandall H, Cullimore ML, Levy ER, Chatani B, Nofziger R, Geha RS, DeRisi J, Campbell AP, Anderson M, Randolph AG. NFKB2 haploinsufficiency identified via screening for IFN-a2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications. J Allergy Clin Immunol. 2023 04; 151(4):926-930.e2.
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Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q. Chicoric acid attenuates tumor necrosis factor-a-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-?B signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model. Int Immunopharmacol. 2022 Oct; 111:109129.
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Cheng W, Cui C, Liu G, Ye C, Shao F, Bagchi AK, Mehta JL, Wang X. NF-?B, A Potential Therapeutic Target in Cardiovascular Diseases. Cardiovasc Drugs Ther. 2023 06; 37(3):571-584.
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Najjar RS, Knapp D, Wanders D, Feresin RG. Raspberry and blackberry act in a synergistic manner to improve cardiac redox proteins and reduce NF-?B and SAPK/JNK in mice fed a high-fat, high-sucrose diet. Nutr Metab Cardiovasc Dis. 2022 07; 32(7):1784-1796.
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Manresa MC, Wu A, Nhu QM, Chiang AWT, Okamoto K, Miki H, Kurten R, Pham E, Duong LD, Lewis NE, Akuthota P, Croft M, Aceves SS. LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LT?R-mediated mechanisms. Mucosal Immunol. 2022 02; 15(2):327-337.
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McCorkell KA, Jayachandran N, Cully MD, Freund-Brown J, Weinkopff T, Monslow J, Hu Y, Pur? E, Freedman BD, Alvarez JI, Cancro MP, May MJ. Lymph node formation and B cell homeostasis require IKK-a in distinct endothelial cell-derived compartments. Proc Natl Acad Sci U S A. 2021 11 30; 118(48).
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Wang L, Howell MEA, Sparks-Wallace A, Zhao J, Hensley CR, Nicksic CA, Horne SR, Mohr KB, Moorman JP, Yao ZQ, Ning S. The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway. mBio. 2021 10 26; 12(5):e0109721.
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Budamagunta V, Manohar-Sindhu S, Yang Y, He Y, Traktuev DO, Foster TC, Zhou D. Senescence-associated hyper-activation to inflammatory stimuli in vitro. Aging (Albany NY). 2021 08 10; 13(15):19088-19107.
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Penthala NR, Balasubramaniam M, Dachavaram SS, Morris EJ, Bhat-Nakshatri P, Ponder J, Jordan CT, Nakshatri H, Crooks PA. Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKK? ubiquitin-like domain (ULD). Eur J Med Chem. 2021 Nov 15; 224:113675.
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Jameson TSO, Pavis GF, Dirks ML, Lee BP, Abdelrahman DR, Murton AJ, Porter C, Alamdari N, Mikus CR, Wall BT, Stephens FB. Reducing NF-?B Signaling Nutritionally is Associated with Expedited Recovery of Skeletal Muscle Function After Damage. J Clin Endocrinol Metab. 2021 06 16; 106(7):2057-2076.
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Land Lail H, Feresin RG, Hicks D, Stone B, Price E, Wanders D. Berries as a Treatment for Obesity-Induced Inflammation: Evidence from Preclinical Models. Nutrients. 2021 Jan 23; 13(2).
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Bj?rklund G, Dosa MD, Maes M, Dadar M, Frye RE, Peana M, Chirumbolo S. The impact of glutathione metabolism in autism spectrum disorder. Pharmacol Res. 2021 04; 166:105437.
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Liu S, Deng X, Zhang P, Wang X, Fan Y, Zhou S, Mu S, Mehta JL, Ding Z. Blood flow patterns regulate PCSK9 secretion via MyD88-mediated pro-inflammatory cytokines. Cardiovasc Res. 2020 08 01; 116(10):1721-1732.
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Han W, Fessel JP, Sherrill T, Kocurek EG, Yull FE, Blackwell TS. Enhanced Expression of Catalase in Mitochondria Modulates NF-?B-Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages. J Immunol. 2020 08 15; 205(4):1125-1134.
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Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, Spearman AD, Sonin DL, Bordas M, Kumar SN, Pan AY, Simpson PM, Strande JL, Bishop E, Zou MH, Ramchandran R. Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart. J Am Heart Assoc. 2019 11 19; 8(22):e012792.
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Mao G, Smyth SS, Morris AJ. Regulation of PLPP3 gene expression by NF-?B family transcription factors. J Biol Chem. 2019 09 20; 294(38):14009-14019.
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Arnold MG, Gokulan K, Doerge DR, Vanlandingham M, Cerniglia CE, Khare S. A single or short time repeated arsenic oral exposure in mice impacts mRNA expression for signaling and immunity related genes in the gut. Food Chem Toxicol. 2019 Oct; 132:110597.
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Cho JJ, Xu Z, Parthasarathy U, Drashansky TT, Helm EY, Zuniga AN, Lorentsen KJ, Mansouri S, Cho JY, Edelmann MJ, Duong DM, Gehring T, Seeholzer T, Krappmann D, Uddin MN, Califano D, Wang RL, Jin L, Li H, Lv D, Zhou D, Zhou L, Avram D. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019 02 11; 10(1):701.
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Cadirci E, Ugan RA, Dincer B, Gundogdu B, Cinar I, Akpinar E, Halici Z. Urotensin receptors as a new target for CLP induced septic lung injury in mice. Naunyn Schmiedebergs Arch Pharmacol. 2019 02; 392(2):135-145.
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Janganati V, Ponder J, Balasubramaniam M, Bhat-Nakshatri P, Bar EE, Nakshatri H, Jordan CT, Crooks PA. MMB triazole analogs are potent NF-?B inhibitors and anti-cancer agents against both hematological and solid tumor cells. Eur J Med Chem. 2018 Sep 05; 157:562-581.
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Flores-Lopez G, Moreno-Lorenzana D, Ayala-Sanchez M, Aviles-Vazquez S, Torres-Martinez H, Crooks PA, Guzman ML, Mayani H, Ch?vez-Gonz?lez A. Parthenolide and DMAPT induce cell death in primitive CML cells through reactive oxygen species. J Cell Mol Med. 2018 10; 22(10):4899-4912.
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Franqui-Machin R, Hao M, Bai H, Gu Z, Zhan X, Habelhah H, Jethava Y, Qiu L, Frech I, Tricot G, Zhan F. Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma. J Clin Invest. 2018 07 02; 128(7):2877-2893.
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Stuart JD, Holm GH, Boehme KW. Differential Delivery of Genomic Double-Stranded RNA Causes Reovirus Strain-Specific Differences in Interferon Regulatory Factor 3 Activation. J Virol. 2018 05 01; 92(9).
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Morgan GJ, He J, Tytarenko R, Patel P, Stephens OW, Zhong S, Deshpande S, Bauer M, Weinhold N, Schinke C, Rasche L, Bailey M, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Zangari M, van Rhee F, Mughal T, Davies FE, Walker BA. Kinase domain activation through gene rearrangement in multiple myeloma. Leukemia. 2018 11; 32(11):2435-2444.
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Nagarajan UM, Tripathy M, Kollipara A, Allen J, Goodwin A, Whittimore J, Wyrick PB, Rank RG. Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp. Immunol Cell Biol. 2018 03; 96(3):246-256.
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Yi SJ, Hwang SY, Oh MJ, Kim YH, Ryu H, Rhee SK, Jhun BH, Kim K. Oncogenic N-Ras Stimulates SRF-Mediated Transactivation via H3 Acetylation at Lysine 9. Biomed Res Int. 2018; 2018:5473725.
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Fouda AM, Youssef AR, Sharaf Eldin O. Comparative study of amlodipine vs. cilnidipine for the prevention of hepatic ischemia-reperfusion injury in rat model. Fundam Clin Pharmacol. 2018 Apr; 32(2):163-173.
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Mendonca MS, Turchan WT, Alpuche ME, Watson CN, Estabrook NC, Chin-Sinex H, Shapiro JB, Imasuen-Williams IE, Rangel G, Gilley DP, Huda N, Crooks PA, Shapiro RH. DMAPT inhibits NF-?B activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo. Free Radic Biol Med. 2017 11; 112:318-326.
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Spurlock CF, Shaginurova G, Tossberg JT, Hester JD, Chapman N, Guo Y, Crooke PS, Aune TM. Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells. J Immunol. 2017 07 15; 199(2):547-558.
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Deng L, Peng Y, Jiang Y, Wu Y, Ding Y, Wang Y, Xu D, Fu Q. Imipramine Protects against Bone Loss by Inhibition of Osteoblast-Derived Microvesicles. Int J Mol Sci. 2017 May 08; 18(5).
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Stein CK, Pawlyn C, Chavan S, Rasche L, Weinhold N, Corken A, Buros A, Sonneveld P, Jackson GH, Landgren O, Mughal T, He J, Barlogie B, Bergsagel PL, Davies FE, Walker BA, Morgan GJ. The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma. Oncotarget. 2017 Apr 25; 8(17):27854-27867.
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Kim HN, Chang J, Shao L, Han L, Iyer S, Manolagas SC, O'Brien CA, Jilka RL, Zhou D, Almeida M. DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age. Aging Cell. 2017 08; 16(4):693-703.
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Salazar G, Huang J, Feresin RG, Zhao Y, Griendling KK. Zinc regulates Nox1 expression through a NF-?B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells. Free Radic Biol Med. 2017 07; 108:225-235.
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Wright F, Hammer M, Paul SM, Aouizerat BE, Kober KM, Conley YP, Cooper BA, Dunn LB, Levine JD, DEramo Melkus G, Miaskowski C. Inflammatory pathway genes associated with inter-individual variability in the trajectories of morning and evening fatigue in patients receiving chemotherapy. Cytokine. 2017 03; 91:187-210.
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Soni NK, Ross AB, Scheers N, Savolainen OI, Nookaew I, Gabrielsson BG, Sandberg AS. Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet. Nutrients. 2017 Jan 10; 9(1).
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Mahapatra S, Gallaher B, Smith SC, Graham JG, Voth DE, Shaw EI. Coxiella burnetii Employs the Dot/Icm Type IV Secretion System to Modulate Host NF-?B/RelA Activation. Front Cell Infect Microbiol. 2016; 6:188.
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Ni HM, McGill MR, Chao X, Woolbright BL, Jaeschke H, Ding WX. Caspase Inhibition Prevents Tumor Necrosis Factor-a-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in?Vivo and in?Vitro. Am J Pathol. 2016 10; 186(10):2623-36.
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Townsend JR, Stout JR, Jajtner AR, Church DD, Beyer KS, Oliveira LP, La Monica MB, Riffe JJ, Muddle TW, Baker KM, Fukuda DH, Roberts MD, Hoffman JR. Resistance exercise increases intramuscular NF-?b signaling in untrained males. Eur J Appl Physiol. 2016 Dec; 116(11-12):2103-2111.
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Fujiwara T, Zhou J, Ye S, Zhao H. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival. Cell Death Dis. 2016 07 21; 7:e2300.
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Sau A, Lau R, Cabrita MA, Nolan E, Crooks PA, Visvader JE, Pratt MA. Persistent Activation of NF-?B in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage. Cell Stem Cell. 2016 07 07; 19(1):52-65.
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Qin B, Wei T, Wang L, Ma N, Tang Q, Liang Y, Yang Z, Zhou L, Zhong R. Decreased expression of TIPE2 contributes to the hyperreactivity of monocyte to Toll-like receptor ligands in primary biliary cirrhosis. J Gastroenterol Hepatol. 2016 Jun; 31(6):1177-83.
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Svahn SL, V?remo L, Gabrielsson BG, Peris E, Nookaew I, Grahnemo L, Sandberg AS, Wernstedt Asterholm I, Jansson JO, Nielsen J, Johansson ME. Six Tissue Transcriptomics Reveals Specific Immune Suppression in Spleen by Dietary Polyunsaturated Fatty Acids. PLoS One. 2016; 11(5):e0155099.
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Liu M, Chen S, Yueh MF, Fujiwara R, Konopnicki C, Hao H, Tukey RH. Cadmium and arsenic override NF-?B developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia. Biochem Pharmacol. 2016 06 15; 110-111:37-46.
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Mao X, Phanavanh B, Hamdan H, Moerman-Herzog AM, Barger SW. NF?B-inducing kinase inhibits NF?B activity specifically in neurons of the CNS. J Neurochem. 2016 Apr; 137(2):154-63.
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Prueitt RL, Wallace TA, Glynn SA, Yi M, Tang W, Luo J, Dorsey TH, Stagliano KE, Gillespie JW, Hudson RS, Terunuma A, Shoe JL, Haines DC, Yfantis HG, Han M, Martin DN, Jordan SV, Borin JF, Naslund MJ, Alexander RB, Stephens RM, Loffredo CA, Lee DH, Putluri N, Sreekumar A, Hurwitz AA, Ambs S. An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers. Cancer Res. 2016 Mar 01; 76(5):1055-1065.
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Ryu S, Johnson A, Park Y, Kim B, Norris D, Armstrong CA, Song PI. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes. PLoS One. 2015; 10(8):e0136887.
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Kim HN, Han L, Iyer S, de Cabo R, Zhao H, O'Brien CA, Manolagas SC, Almeida M. Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs. Mol Endocrinol. 2015 Oct; 29(10):1498-509.
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Smith EM, Zhang L, Walker BA, Davenport EL, Aronson LI, Krige D, Hooftman L, Drummond AH, Morgan GJ, Davies FE. The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NF?B signalling pathway. Oncotarget. 2015 Jul 10; 6(19):17314-27.
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Ding Z, Liu S, Wang X, Deng X, Fan Y, Shahanawaz J, Shmookler Reis RJ, Varughese KI, Sawamura T, Mehta JL. Cross-talk between LOX-1 and PCSK9 in vascular tissues. Cardiovasc Res. 2015 Sep 01; 107(4):556-67.
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Kundumani-Sridharan V, Subramani J, Das KC. Thioredoxin Activates MKK4-NF?B Pathway in a Redox-dependent Manner to Control Manganese Superoxide Dismutase Gene Expression in Endothelial Cells. J Biol Chem. 2015 Jul 10; 290(28):17505-19.
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Chang WC, Wu SL, Huang WC, Hsu JY, Chan SH, Wang JM, Tsai JP, Chen BK. PTX3 gene activation in EGF-induced head and neck cancer cell metastasis. Oncotarget. 2015 Apr 10; 6(10):7741-57.
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Gu Z, Wang H, Xia J, Yang Y, Jin Z, Xu H, Shi J, De Domenico I, Tricot G, Zhan F. Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation. Cancer Res. 2015 Jun 01; 75(11):2211-21.
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Sereno J, Vala H, Nunes S, Rocha-Pereira P, Carvalho E, Alves R, Teixeira F, Reis F. Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat. J Physiol Pharmacol. 2015 Apr; 66(2):285-99.
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Kang J, Thakali KM, Jensen GS, Wu X. Phenolic acids of the two major blueberry species in the US Market and their antioxidant and anti-inflammatory activities. Plant Foods Hum Nutr. 2015 Mar; 70(1):56-62.
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Ding Z, Liu S, Wang X, Khaidakov M, Fan Y, Deng X, Xiang D, Mehta JL. Lectin-like oxidized low-density lipoprotein receptor-1 regulates autophagy and Toll-like receptor 4 in the brain of hypertensive mice. J Hypertens. 2015 Mar; 33(3):525-33; discussion 533.
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Mohamed RH, Karam RA, Hagrass HA, Amer MG, Abd El-Haleem MR. Anti-apoptotic effect of spermatogonial stem cells on doxorubicin-induced testicular toxicity in rats. Gene. 2015 Apr 25; 561(1):107-14.
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Cullen S, Ponnappan S, Ponnappan U. Redox-regulated pathway of tyrosine phosphorylation underlies NF-?B induction by an atypical pathway independent of the 26S proteasome. Biomolecules. 2015 Feb 09; 5(1):95-112.
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Ding Z, Liu S, Wang X, Deng X, Fan Y, Sun C, Wang Y, Mehta JL. Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta. Antioxid Redox Signal. 2015 Mar 20; 22(9):760-71.
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Zhou H, Chen JX, Yang CS, Yang MQ, Deng Y, Wang H. Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer. BMC Genomics. 2014; 15 Suppl 11:S3.
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Ryu S, Park Y, Kim B, Cho SM, Lee J, Lee HH, Gurley C, Song K, Johnson A, Armstrong CA, Song PI. Inhibitory and anti-inflammatory effects of the Helicobacter pylori-derived antimicrobial peptide HPA3NT3 against Propionibacterium acnes in the skin. Br J Dermatol. 2014 Dec; 171(6):1358-67.
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Hasan SK, Khan R, Ali N, Khan AQ, Rehman MU, Tahir M, Lateef A, Nafees S, Mehdi SJ, Rashid S, Shahid A, Sultana S. 18-? Glycyrrhetinic acid alleviates 2-acetylaminofluorene-induced hepatotoxicity in Wistar rats: Role in hyperproliferation, inflammation and oxidative stress. Hum Exp Toxicol. 2015 Jun; 34(6):628-41.
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Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Cancer-selective targeting of the NF-?B survival pathway with GADD45?/MKK7 inhibitors. Cancer Cell. 2014 10 13; 26(4):495-508.
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Brioli A, Melchor L, Walker BA, Davies FE, Morgan GJ. Biology and treatment of myeloma. Clin Lymphoma Myeloma Leuk. 2014 Sep; 14 Suppl:S65-70.
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Sullivan CB, Porter RM, Evans CH, Ritter T, Shaw G, Barry F, Murphy JM. TNFa and IL-1? influence the differentiation and migration of murine MSCs independently of the NF-?B pathway. Stem Cell Res Ther. 2014 Aug 27; 5(4):104.
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Pathak R, Shao L, Chafekar SM, Feng W, Ponnappan U, Fink LM, Zhou D, Hauer-Jensen M. IKK? regulates endothelial thrombomodulin in a Klf2-dependent manner. J Thromb Haemost. 2014 Sep; 12(9):1533-1544.
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Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T, Verstovsek S, Yoder MC, Kapur R, Cardoso AA, Carlesso N. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-?B-dependent manner. Cell Stem Cell. 2014 Jul 03; 15(1):51-65.
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Dai L, DeFee MR, Cao Y, Wen J, Wen X, Noverr MC, Qin Z. Lipoteichoic acid (LTA) and lipopolysaccharides (LPS) from periodontal pathogenic bacteria facilitate oncogenic herpesvirus infection within primary oral cells. PLoS One. 2014; 9(6):e101326.
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Dai Y, Palade P, Wang X, Mercanti F, Ding Z, Dai D, Mehta JL. High fat diet causes renal fibrosis in LDLr-null mice through MAPK-NF-?B pathway mediated by Ox-LDL. J Cardiovasc Pharmacol. 2014 Feb; 63(2):158-66.
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Li B, Abdalrahman A, Lai Y, Janicki JS, Ward KW, Meyer CJ, Wang XL, Tang D, Cui T. Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2. Biochem Biophys Res Commun. 2014 Feb 21; 444(4):555-61.
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Matthews KL, Coleman CM, van der Meer Y, Snijder EJ, Frieman MB. The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling. J Gen Virol. 2014 Apr; 95(Pt 4):874-882.
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Stebbing RE, Irvin SC, Rivera-Serrano EE, Boehme KW, Ikizler M, Yoder JA, Dermody TS, Sherry B. An ITAM in a nonenveloped virus regulates activation of NF-?B, induction of beta interferon, and viral spread. J Virol. 2014 Mar; 88(5):2572-83.
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Mohamed IN, Hafez SS, Fairaq A, Ergul A, Imig JD, El-Remessy AB. Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet. Diabetologia. 2014 Feb; 57(2):413-23.
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Dai Y, Mehta JL, Chen M. Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation. Cardiovasc Drugs Ther. 2013 Oct; 27(5):371-80.
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