 MutS Homolog 2 Protein
"MutS Homolog 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
MutS homolog 2 protein is found throughout eukaryotes and is a homolog of the MUTS DNA MISMATCH-BINDING PROTEIN. It plays an essential role in meiotic RECOMBINATION and DNA REPAIR of mismatched NUCLEOTIDES.
| Descriptor ID |
D051718
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| MeSH Number(s) |
D08.811.074.812 D08.811.277.040.025.281 D12.776.260.551 D12.776.624.664.700.130
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "MutS Homolog 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "MutS Homolog 2 Protein".
This graph shows the total number of publications written about "MutS Homolog 2 Protein" by people in UAMS Profiles by year, and whether "MutS Homolog 2 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 2 | 2 | | 2016 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2006 | 1 | 2 | 3 | | 2004 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "MutS Homolog 2 Protein" by people in Profiles over the past ten years.
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Pearlman R, Markow M, Knight D, Chen W, Arnold CA, Pritchard CC, Hampel H, Frankel WL. Two-stain immunohistochemical screening for Lynch syndrome in colorectal cancer may fail to detect mismatch repair deficiency. Mod Pathol. 2018 12; 31(12):1891-1900.
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Roberts ME, Jackson SA, Susswein LR, Zeinomar N, Ma X, Marshall ML, Stettner AR, Milewski B, Xu Z, Solomon BD, Terry MB, Hruska KS, Klein RT, Chung WK. MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer. Genet Med. 2018 10; 20(10):1167-1174.
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Haraldsdottir S, Roth R, Pearlman R, Hampel H, Arnold CA, Frankel WL. Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasis. Fam Cancer. 2016 Apr; 15(2):253-60.
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Hassen S, Ali AA, Kilaparty SP, Al-Anbaky QA, Majeed W, Boman BM, Fields JZ, Ali N. Interdependence of DNA mismatch repair proteins MLH1 and MSH2 in apoptosis in human colorectal carcinoma cell lines. Mol Cell Biochem. 2016 Jan; 412(1-2):297-305.
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