 Rad51 Recombinase
"Rad51 Recombinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Rec A recombinase found in eukaryotes. Rad51 is involved in DNA REPAIR of double-strand breaks.
| Descriptor ID |
D051135
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| MeSH Number(s) |
D08.811.739.650.500 D12.776.260.695
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rad51 Recombinase".
Below are MeSH descriptors whose meaning is more specific than "Rad51 Recombinase".
This graph shows the total number of publications written about "Rad51 Recombinase" by people in UAMS Profiles by year, and whether "Rad51 Recombinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2020 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rad51 Recombinase" by people in Profiles over the past ten years.
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de la Pe?a Avalos B, Paquet N, Trop?e R, Coulombe Y, Palacios H, Leung JW, Masson JY, Duijf PHG, Dray E. The protein phosphatase EYA4 promotes homologous recombination (HR) through dephosphorylation of tyrosine 315 on RAD51. Nucleic Acids Res. 2024 Feb 09; 52(3):1173-1187.
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Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK. Structural insights into BCDX2 complex function in homologous recombination. Nature. 2023 Jul; 619(7970):640-649.
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Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T. PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells. Signal Transduct Target Ther. 2021 03 31; 6(1):129.
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Traver G, Sekhar KR, Crooks PA, Keeney DS, Freeman ML. Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC. Cancer Lett. 2021 03 01; 500:220-227.
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Liang F, Miller AS, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Zhao W, Sung P, Kupfer GM. The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair. J Biol Chem. 2020 06 12; 295(24):8186-8194.
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Yu H, Harrison FE, Xia F. Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. Sci Rep. 2018 04 04; 8(1):5600.
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Alagpulinsa DA, Yaccoby S, Ayyadevara S, Shmookler Reis RJ. A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment. Cancer Biol Ther. 2015; 16(6):976-86.
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Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML. Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization. Int J Radiat Oncol Biol Phys. 2014 Aug 01; 89(5):1106-1114.
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