 Retinoblastoma Protein
"Retinoblastoma Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
| Descriptor ID |
D016160
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| MeSH Number(s) |
D12.776.260.704 D12.776.624.776.745 D12.776.660.807 D12.776.744.770
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| Concept/Terms |
p105-Rb Protein- p105-Rb Protein
- p105 Rb Protein
- Retinoblastoma Nuclear Phosphoprotein p105-Rb
- Retinoblastoma Nuclear Phosphoprotein p105 Rb
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma Protein".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma Protein".
This graph shows the total number of publications written about "Retinoblastoma Protein" by people in UAMS Profiles by year, and whether "Retinoblastoma Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2002 | 1 | 1 | 2 | | 2000 | 1 | 1 | 2 | | 1999 | 1 | 2 | 3 | | 1997 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma Protein" by people in Profiles over the past ten years.
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Cloutier JM, Shalin SC, Lindberg M, Gardner JM, Fernandez-Pol S, Zaba L, Novoa R, Brown RA. Cutaneous pleomorphic fibromas arising in patients with germline TP53 mutations. J Cutan Pathol. 2020 Aug; 47(8):734-741.
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Delgado M, Chambers TC. Microtubules play an essential role in the survival of primary acute lymphoblastic leukemia cells advancing through G1 phase. Cell Cycle. 2018; 17(14):1784-1796.
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Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y. Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight. 2017 09 07; 2(17).
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Aydin Y, Chedid M, Chava S, Danielle Williams D, Liu S, Hagedorn CH, Sumitran-Holgersson S, Reiss K, Moroz K, Lu H, Balart LA, Dash S. Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture. Sci Rep. 2017 08 23; 7(1):9223.
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Chavan SS, He J, Tytarenko R, Deshpande S, Patel P, Bailey M, Stein CK, Stephens O, Weinhold N, Petty N, Steward D, Rasche L, Bauer M, Ashby C, Peterson E, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Schinke C, Zangari M, van Rhee F, Barlogie B, Mughal TI, Davies FE, Morgan GJ, Walker BA. Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker. Blood Cancer J. 2017 02 24; 7(2):e535.
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