A form of stimulus sensitive myoclonic epilepsy inherited as an autosomal recessive condition. The most common presenting feature is a single seizure in the second decade of life. This is followed by progressive myoclonus, myoclonic seizures, tonic-clonic seizures, focal occipital seizures, intellectual decline, and severe motor and coordination impairments. Most affected individuals do not live past the age of 25 years. Concentric amyloid (Lafora) bodies are found in neurons, liver, skin, bone, and muscle (From Menkes, Textbook of Childhood Neurology, 5th ed, pp111-110)

Descriptor ID	D020192
MeSH Number(s)	C10.228.140.490.250.650.500 C10.574.500.529 C16.320.400.480
Concept/Terms	Lafora Disease Lafora Disease Disease, Lafora Progressive Myoclonic Epilepsy, Lafora Progressive Myoclonic Epilepsy, Lafora Type Lafora Body Disorder Body Disorder, Lafora Disorder, Lafora Body Epilepsy, Progressive Myoclonic 2a Epilepsy Progressive Myoclonic 2 Epilepsy, Progressive Myoclonic, Lafora Lafora Body Disease Disease, Lafora Body Lafora Progressive Myoclonic Epilepsy Lafora Type Progressive Myoclonic Epilepsy Myoclonic Epilepsy of Lafora Lafora Myoclonic Epilepsy Lafora Body Disease, Late Onset Lafora Body Disease, Late Onset Late Onset Lafora Body Disease Lafora-Body Disease, Late Onset

Below are MeSH descriptors whose meaning is more general than "Lafora Disease".

Below are MeSH descriptors whose meaning is related to "Lafora Disease".

Below are MeSH descriptors whose meaning is more specific than "Lafora Disease".