 Alexander Disease
"Alexander Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.
| Descriptor ID |
D038261
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| MeSH Number(s) |
C10.228.140.163.100.362.312 C10.228.140.695.625.312 C10.228.518.625.312 C10.314.400.312 C10.574.500.024 C16.320.400.024 C16.320.565.189.362.312 C18.452.132.100.362.312 C18.452.648.189.362.312
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alexander Disease".
- Diseases [C]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Brain Diseases, Metabolic [C10.228.140.163]
- Brain Diseases, Metabolic, Inborn [C10.228.140.163.100]
- Hereditary Central Nervous System Demyelinating Diseases [C10.228.140.163.100.362]
- Alexander Disease [C10.228.140.163.100.362.312]
- Leukoencephalopathies [C10.228.140.695]
- Hereditary Central Nervous System Demyelinating Diseases [C10.228.140.695.625]
- Alexander Disease [C10.228.140.695.625.312]
- Leukoencephalopathies [C10.228.518]
- Hereditary Central Nervous System Demyelinating Diseases [C10.228.518.625]
- Alexander Disease [C10.228.518.625.312]
- Demyelinating Diseases [C10.314]
- Hereditary Central Nervous System Demyelinating Diseases [C10.314.400]
- Alexander Disease [C10.314.400.312]
- Neurodegenerative Diseases [C10.574]
- Heredodegenerative Disorders, Nervous System [C10.574.500]
- Alexander Disease [C10.574.500.024]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Heredodegenerative Disorders, Nervous System [C16.320.400]
- Alexander Disease [C16.320.400.024]
- Metabolism, Inborn Errors [C16.320.565]
- Brain Diseases, Metabolic, Inborn [C16.320.565.189]
- Hereditary Central Nervous System Demyelinating Diseases [C16.320.565.189.362]
- Alexander Disease [C16.320.565.189.362.312]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Brain Diseases, Metabolic [C18.452.132]
- Brain Diseases, Metabolic, Inborn [C18.452.132.100]
- Hereditary Central Nervous System Demyelinating Diseases [C18.452.132.100.362]
- Alexander Disease [C18.452.132.100.362.312]
- Metabolism, Inborn Errors [C18.452.648]
- Brain Diseases, Metabolic, Inborn [C18.452.648.189]
- Hereditary Central Nervous System Demyelinating Diseases [C18.452.648.189.362]
- Alexander Disease [C18.452.648.189.362.312]
Below are MeSH descriptors whose meaning is more specific than "Alexander Disease".
This graph shows the total number of publications written about "Alexander Disease" by people in UAMS Profiles by year, and whether "Alexander Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Alexander Disease" by people in Profiles over the past ten years.
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