A mitochondrial encephalomyopathy characterized clinically by a mixed seizure disorder, myoclonus, progressive ataxia, spasticity, and a mild myopathy. Dysarthria, optic atrophy, growth retardation, deafness, and dementia may also occur. This condition tends to present in childhood and to be transmitted via maternal lineage. Muscle biopsies reveal ragged-red fibers and respiratory chain enzymatic defects. (From Adams et al., Principles of Neurology, 6th ed, p986)

Descriptor ID	D017243
MeSH Number(s)	C05.651.460.620.530 C10.228.140.163.100.545 C10.228.140.490.250.650.700 C10.668.491.500.500.550 C16.320.565.189.545 C18.452.132.100.545 C18.452.648.189.545 C18.452.660.560.620.530
Concept/Terms	MERRF Syndrome MERRF Syndrome Syndrome, MERRF Fukuhara Syndrome Syndrome, Fukuhara Myoencephalopathy Ragged-Red Fiber Disease Myoencephalopathy Ragged Red Fiber Disease Myoclonic Epilepsy Associated with Ragged-Red Fibers Myoclonic Epilepsy Associated with Ragged Red Fibers Myoclonic Epilepsy with Ragged Red Fibers Myoclonus with Epilepsy with Ragged Red Fibers Fukuhara Disease Myoclonic Epilepsy and Ragged Red Fibers

Below are MeSH descriptors whose meaning is more general than "MERRF Syndrome".

Below are MeSH descriptors whose meaning is related to "MERRF Syndrome".

Below are MeSH descriptors whose meaning is more specific than "MERRF Syndrome".