 Synaptic Transmission
"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
| Descriptor ID |
D009435
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| MeSH Number(s) |
G02.111.087.800.850 G02.149.115.800.850 G04.299.880.850 G07.265.337.900 G07.700.240.900 G11.561.600.835
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| Concept/Terms |
Synaptic Transmission- Synaptic Transmission
- Neurotransmission
- Transmission, Synaptic
- Transmission, Neural
- Neural Transmission
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Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".
Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".
This graph shows the total number of publications written about "Synaptic Transmission" by people in UAMS Profiles by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2022 | 1 | 1 | 2 | | 2019 | 2 | 1 | 3 | | 2018 | 1 | 1 | 2 | | 2016 | 2 | 1 | 3 | | 2015 | 0 | 2 | 2 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2012 | 2 | 1 | 3 | | 2011 | 1 | 1 | 2 | | 2010 | 3 | 2 | 5 | | 2009 | 2 | 0 | 2 | | 2008 | 2 | 4 | 6 | | 2007 | 1 | 4 | 5 | | 2006 | 2 | 3 | 5 | | 2005 | 1 | 3 | 4 | | 2004 | 3 | 4 | 7 | | 2002 | 0 | 2 | 2 | | 2001 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 1999 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1991 | 3 | 2 | 5 | | 1990 | 1 | 1 | 2 | | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synaptic Transmission" by people in Profiles over the past ten years.
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Lu H, Zuo L, Roddick KM, Zhang P, Oku S, Garden J, Ge Y, Bellefontaine M, Delhaye M, Brown RE, Craig AM. Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors. Cell Rep. 2023 07 25; 42(7):112714.
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Dienel GA, Schousboe A, McKenna MC, Rothman DL. A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies. J Neurochem. 2024 05; 168(5):461-495.
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Rothman DL, Behar KL, Dienel GA. Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo-malate-aspartate shuttle model. J Neurochem. 2024 05; 168(5):555-591.
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Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S. Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. J Cereb Blood Flow Metab. 2022 05; 42(5):844-860.
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Sengar AS, Li H, Zhang W, Leung C, Ramani AK, Saw NM, Wang Y, Tu Y, Ross PJ, Scherer SW, Ellis J, Brudno M, Jia Z, Salter MW. Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1. Cell Rep. 2019 12 24; 29(13):4285-4294.e5.
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Dienel GA. Does shuttling of glycogen-derived lactate from astrocytes to neurons take place during neurotransmission and memory consolidation? J Neurosci Res. 2019 08; 97(8):863-882.
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Dienel GA. Brain Glucose Metabolism: Integration of Energetics with Function. Physiol Rev. 2019 01 01; 99(1):949-1045.
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Yang F, Anderson M, He S, Stephens K, Zheng Y, Chen Z, Raja SN, Aplin F, Guan Y, Fridman G. Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current. Sci Adv. 2018 04; 4(4):eaaq1438.
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Perissinotti PP, Rivero-Echeto MC, Garcia-Rill E, Bisagno V, Urbano FJ. Leptin alters somatosensory thalamic networks by decreasing gaba release from reticular thalamic nucleus and action potential frequency at ventrobasal neurons. Brain Struct Funct. 2018 Jun; 223(5):2499-2514.
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Carlson GM, Dienel GA, Colbran RJ. Introduction to the Thematic Minireview Series: Brain glycogen metabolism. J Biol Chem. 2018 05 11; 293(19):7087-7088.
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Lee SH, Dudok B, Parihar VK, Jung KM, Z?ldi M, Kang YJ, Maroso M, Alexander AL, Nelson GA, Piomelli D, Katona I, Limoli CL, Soltesz I. Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission. Brain Struct Funct. 2017 Jul; 222(5):2345-2357.
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Saur T, Cohen BM, Ma Q, Babb SM, Buttner EA, Yao WD. Acute and chronic effects of clozapine on cholinergic transmission in cultured mouse superior cervical ganglion neurons. J Neurogenet. 2016 Sep - Dec; 30(3-4):297-305.
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Zhang WB, Ross PJ, Tu Y, Wang Y, Beggs S, Sengar AS, Ellis J, Salter MW. Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons. Sci Rep. 2016 Apr 04; 6:23837.
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Salvatore MF, Terrebonne J, Fields V, Nodurft D, Runfalo C, Latimer B, Ingram DK. Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine. Neurobiol Aging. 2016 Jan; 37:192-207.
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Soltesz I, Alger BE, Kano M, Lee SH, Lovinger DM, Ohno-Shosaku T, Watanabe M. Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy. Nat Rev Neurosci. 2015 May; 16(5):264-77.
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